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Colegio de Medicina Interna de México.

2022, Number 6

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Med Int Mex 2022; 38 (6)

Probabilistic analysis of cardiac dynamics for 20 hours in diabetic patients

Rodríguez-Velásquez JO, Correa-Herrera SC, Salazar-Flórez J, Prieto-Bohórquez SE, Valdés-Cadena, CA

Language: Spanish
References: 24
Page: 1147-1154
PDF size: 208.98 Kb.


ABSTRACT

Objective: To test the diagnostic performance of a methodology based on probability theory applied for 20 hours analyzing Holter records of diabetic subjects and to confirm its clinical applicability.
Materials and Methods: A prospective observational study was made in which Holter records were collected from December 2019 to June 2020. The minimum and maximum heart rate values were extracted as well as the number of beats per hour to apply the diagnostic criteria of the probabilistic methodology through a blinded study. Sensitivity and specificity values were calculated.
Results: A total of 48 Holter records were collected, which included 30, 14 and 4 records of subjects with cardiovascular disease without diabetes, with cardiovascular disease and diabetes, and with diabetes without heart disease, respectively. The cardiac dynamics of diabetic patients exhibited a mathematical behavior that varied between the disease and the evolution to the disease, similar to the cardiac dynamics of subjects with cardiovascular disease. The sensitivity and specificity values were 97% and 100%, respectively.
Conclusions: The clinical applicability of a diagnostic methodology of cardiac dynamics in the context of diabetes mellitus and cardiovascular disease was confirmed, suggesting that this method is applicable to describe cardiac risk in this population.


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