2023, Number 1
<< Back Next >>
Aten Fam 2023; 30 (1)
Cognitive Impairment Associated with Obesity in Adults in a General Hospital in Cuernavaca, Morelos
Soriano-Ursua IG, Piña-Ramírez NI, Albavera-Hernández C, Ávila-Jiménez L
Language: Spanish
References: 28
Page: 61-67
PDF size: 164.77 Kb.
ABSTRACT
Objective: To estimate the association
between cognitive impairment and
obesity in adults.
Methods: analytical
cross-sectional study with a non-probabilistic
sample of consecutive cases. 112
participants aged 20 to 64 years were
included, with normal weight and obesity,
who attended the outpatient Family
Medicine clinic of the Regional General
Hospital No. 1, in Cuernavaca, Morelos,
Mexico. The Montreal Cognitive Assessment
Scale was used and covariates such
as physical activity, caloric intake, sex,
age, waist circumference and body fat
percentage were evaluated. Data were
analyzed with the statistical program
stata 11.1.
Results: 112 participants, 23
men and 89 women; age range 20 to 64
years (median 30 years). Statistically significant
differences (p‹0.05) were found
between the groups with and without
cognitive impairment in the variables:
schooling, age, visceral fat level, body
fat percentage, waist circumference, and
muscle quality. After adjusting for age,
sex, level of education, physical activity,
and daily calorie intake, obesity was
significantly associated with an increase
in the possibility of presenting cognitive
impairment (MR = 3.77, 95% CI = 1.004-
14.190, p ‹0.04).
Conclusion: obesity
was associated with a higher possibility of
presenting cognitive impairment, while
higher schooling was associated with a
lower possibility of presenting cognitive
impairment.
REFERENCES
Maxine A, Papadakis S. Diagnóstico clínico y tratamiento.Radow MW. Vol. 56 th. McGrawHillEducation; 2017.
WHO. Obesity and overweight [Internet]. [Citado2021 Nov 2]. Disponible en: https://www.who.int/news-room/fact-sheets/detail/obesity-andoverweight
Encuesta Nacional de Salud y Nutrición 2018[Internet]. [Citado 2021 Nov 2]. Disponible en:https://ensanut.insp.mx/encuestas/ensanut2018/doctos/informes/ensanut_2018_presentacion_resultados.pdf
Cervantes-Arriaga A, Calleja-Castillo J, Rodríguez-Violante M. Función cognitiva y factores cardiometabólicosen diabetes mellitus tipo 2. MedInterna México. 2009;25(5):386-92.
World Alzheimer Report 2015: The global impactof dementia: An analysis of prevalence, incidence,cost and trends [Internet]. [Citado 2021 Nov 7].Disponible en: https://www.alzint.org/resource/world-alzheimer-report-2015/
Allegri RF, Arizaga RL, Bavec CV, Colli LP, DemeyI, Fernández MC, et al. Enfermedad de Alzheimer.Guía de práctica clínica. Neurol Argent.2011;3(2):120-37.
Prince M, Bryce R, Albanese E, Wimo A, RibeiroW, Ferri CP. The global prevalence of dementia:a systematic review and metaanalysis. AlzheimersDement J. 2013;9(1):63-75.e2.
Greenwood CE, Winocur G. Learning and memoryimpairment in rats fed a high saturated fat diet.Behav Neural Biol.1990;53(1):74-87.
Greenwood CE, Winocur G. Glucose treatmentreduces memory deficits in young adultrats fed high-fat diets. Neurobiol Learn Mem.2001;75(2):179-89.
Miller AA, Spencer SJ. Obesity and neuroinflammation:A pathway to cognitive impairment. BrainBehav Immun. 2014;42:10-21.
Liu Y, Yu J, Shi YC, Zhang Y, Lin S. The role ofinflammation and endoplasmic reticulum stressin obesity-related cognitive impairment. Life Sci.2019;233:116707.
Rafnsson SB, Deary IJ, Fowkes FGR. Peripheralarterial disease and cognitive function. Vasc MedLond Engl. 2009;14(1):51-61.
Farruggia MC, Small DM. Effects of adiposityand metabolic dysfunction on cognition: A review.Physiol Behav. 2019;208:112578.
Alosco ML, Cohen R, Spitznagel MB, Strain G,Devlin M, Crosby RD, et al. Older age does notlimit postbariatric surgery cognitive benefits: apreliminary investigation. Surg Obes Relat Dis.2014;10(6):1196-201.
Alosco ML, Galioto R, Spitznagel MB, Strain G,Devlin M, Cohen R, et al. Cognitive function afterbariatric surgery: evidence for improvement 3years after surgery. Am J Surg. 2014;207(6):870-6.
Chang YK, Chu CH, Chen FT, Hung TM, EtnierJL. Combined Effects of Physical Activityand Obesity on Cognitive Function: Independent,Overlapping, Moderator, and Mediator Models.Sports Med. 2017;47(3):449-68.
Smith PJ, Blumenthal JA, Hoffman BM, CooperH, Strauman TA, Welsh-Bohmer K, et al. AerobicExercise and Neurocognitive Performance: AMeta-Analytic Review of Randomized ControlledTrials. Psychosom Med. 2010;72(3):239-52.
Hackett A. Food Frequency Questionnaires: simpleand cheap, but are they valid? Matern ChildNutr. 2011;7(2):109-11.
Booth M. Assessment of physical activity: aninternational perspective. Res Q Exerc Sport.
2000;71(2):S114-20.20. Aguilar-Navarro SG, Mimenza-Alvarado AJ, Palacios-García AA, Samudio-Cruz A, Gutiérrez-GutierrezLA, Ávila-Funes JA. Validez y confiabilidaddel MoCA (Montreal Cognitive Assessment) parael tamizaje del deterioro cognoscitivo en México.Rev Colomb Psiquiatr. 2018;47(4):237-43.
Catenacci VA, Hill JO, Wyatt HR. The obesityepidemic. Clin Chest Med. 2009;30(3):415-44.
Moyer VA, U.S. Preventive Services Task Force.Screening for and management of obesity inadults: U.S. Preventive Services Task Force recommendationstatement. Ann Intern Med.2012;157(5):373-8.
Figley CR, Asem JSA, Levenbaum EL, CourtneySM. Effects of Body Mass Index and Body FatPercent on Default Mode, Executive Control, andSalience Network Structure and Function. FrontNeurosci. 2016;10:234.
Beydoun MA, Beydoun HA, Wang Y. Obesity andcentral obesity as risk factors for incident dementiaand its subtypes: a systematic review and metaanalysis.Obes Rev Off J Int Assoc Study Obes.2008;9(3):204-18.
Lentoor AG, Myburgh L. Correlation betweenBody Mass Index (BMI) and Performance on theMontreal Cognitive Assessment (MoCA) in a Cohortof Adult Women in South Africa. Behav Neurol.2022;2:8994793.
Ala Abu Saleh RS, Nimer Assy. Cognitive Dysfunctionin Obese Individuals With or WithoutMetabolic Risk Factors. Neurology. 2015;84:I12-5A.
Alcaraz-Ortíz MR, Ramírez-Flores D, Palafox-LópezGI Reyes-Hernández JU. El déficit cognitivorelacionado con el índice de masa corporal elevado.Rev Esp Cienc Salud. 2015;18(1):33-8.
Vidyanti AN, Hardhantyo M, Wiratama BS,Prodjohardjono A, Hu C-J. Obesity Is Less FrequentlyAssociated with Cognitive Impairment inElderly Individuals: A Cross-Sectional Study in Yogyakarta,Indonesia. Nutrients. 2020;12(2):367.