2021, Number 2
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Revista Cubana de Ortopedia y Traumatología 2021; 35 (2)
Incidence of infection in a historical cohort from the national registry of 1738 hip arthroplasties operated for osteoarthritis in 2014 in Uruguay
Rodríguez BM, Albornoz SH, Costa AC, Saona OG, Rey NR
Language: Spanish
References: 20
Page:
PDF size: 324.06 Kb.
ABSTRACT
Introduction:
Total hip arthroplasty infections have a low incidence, but when they occur they generate health problems for the patient, and for the health system. They can cause pain, decreased functional capacity, poor quality of life, multiple surgeries, and sometimes death.
Objectives:
To evaluate the national incidence of infections in primary hip arthroplasties operated for osteoarthritis in 2014, and the risk factors related to the patient, the environment and the surgical act, including the surgical approach.
Methods:
Analytical observational study of all patients operated on for osteoarthritis. A random sample of 633 patients was selected, representative of 1738 arthroplasties performed in Uruguay in 2014. Through a telephone interview and review of medical records, patients with deep infection of the surgical site were identified. The incidence of infection was estimated and univariate and multivariate analysis was performed using logistic regression to identify factors associated with deep periprosthetic infection.
Results:
There were 8 infections, with an incidence of 1.21% (95% CI 0.59 - 2.20) in the general population. The statistically significant factors associated with prosthetic infection were: a) BMI ≥ 35, p = 0.006; b) origin of Montevideo 2.07% (1.03 - 4.11) p = 0.031; c) origin of the private subsector 1.47% (0.77 - 2.78) p = 0.009; d) surgical center where the surgery was performed 4.3% (1.6 - 10.9) p = 0.03, e) use of cement with antibiotic 1.59% (0.65 - 3.25) p = 0.034. Suspicion of infection was presented in 6 of 8 patients, in the first 30 postoperative days; 7 of 8 patients underwent surgical cleaning and only 1 of 8 patients underwent final prosthetic revision.
Conclusions:
The incidence of infection in elective prosthetic hip surgery for osteoarthritis in the Uruguayan National Registry was similar to that published in the literature. Body mass index was the only variable associated as incidental to this complication in this series, out of those frequently cited. The associations depending on the origin, socioeconomic level and surgical center are striking. The results regarding the use of cement with antibiotics should be evaluated in future studies.
REFERENCES
Learmonth ID, Young C, Rorabeck C. The operation of the century: total hip replacement. Lancet. 2007;370:1508-19.
NICE. Total hip replacement and resurfacing arthroplasty for end stage arthritis of the hip. NICE technology appraisal guidance 304. London: National Institute for Health and Care Excellence; 2014.
Evans J, Walker R, Blom A, Whitehouse M, Sayers A. How long does a hip replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of followup. Lancet. 2019;393:647-54.
Kunutsor SK, Whitehouse MR, Blom AW, Beswick AD. Patient-Related Risk Factors for Periprosthetic Joint Infection after Total Joint Arthroplasty: A Systematic Review and Meta-Analysis. PLoS One. 2016 March;11(3):1-18.
Diaz-Ledesma C, Higuera C, Parvizi H. Succes after treatment of Periposthetic Joint Infection: A delphi-based international multidisciplinary consensus. Clin Orthop Relat Res. 2013 Jul;471(7):2374-82.
Wasterlain A, Goswami K, Ghasemi S, Parvizi J. What is de definition of a periprosthetic joint infection (PJI) of the knee and the hip? Can the same criteria be used for both joints? Second International consensus meeting (ICM) of musculoskeletal infection. The Journal of Arthroplasty. 2018 May;33(5):1309-14.
Lindeque B, Hartman Z, Noshchenko A, Cruse M. Infection After Primary Total Hip Arthroplasty. Orthopedics. 2014;37(4):257-65.
Fondo Nacional de Recursos Medicina Altamente Especializada. [acceso 01/08/2017] Disponible en: https://www.fnr.gub.uy/tecnicasbeneficiarios
Ibarra Melogno SL, Chifflet RR, Leiva N, Morales Albornoz H. Resultados a largo plazo de artroplastia de cadera en pacientes en diálisis por insuficiencia renal crónica. Mortalidad y supervivencia del implante en el Registro Nacional de Uruguay desde el año 2000. Rev Esp Cir Ortop Traumatol (Eng. ed.). May-Jun 2019.
Lindgren V, Gordon M, Wretenberg P, Kärrholm J, Garellick G. Deep Infection after Total Hip Replacement: A Method for National Incidence Surveillance. Infect Control Hosp Epidemiol. 2014;35(12):1491-6.
Parvizi J, Tan TL, Goswami K, Higuera C, Della Valle C, Chen AF, et al. The 2018 Definition of Periprosthetic Hip and Knee Infection: An Evidence-Based and Validated Criteria. J Arthroplasty. 2018;33(5):1309-14.
Berbari EF, Marculescu C, Sia I, Lahr BD, Hanssen AD, Steckelberg JM, et al. Culture-Negative Prosthetic Joint Infection. Clin Infect Dis. 2007;45(9):1113-9.
Dale H, Skråmm I, Løwer HL, Eriksen HM, Espehaug B, Furnes O, et al. Infection after primary hip arthroplasty: A comparison of 3 Norwegian health registers. Acta Orthop. 2011;82(6):646-54.
Dale H, Fenstad AM, Hallan G, Havelin LI, Furnes O, Overgaard S, et al. Increasing risk of prosthetic joint infection after total hip arthroplasty. Acta Orthop. 2012;83(5):449-58.
Namba RS, Inacio MCS, Paxton EW. Risk factors associated with surgical site infection in 30 491 primary total hip replacements. Bone Joint J. 2012;94-B(10):1330-8.
Triantafyllopoulos G, Stundner O, Memtsoudis S, Poultsides LA. Patient, Surgery, and Hospital Related Risk Factors for Surgical Site Infections following Total Hip Arthroplasty. Sci World J. 2015:1-9.
Kennedy JW, Young D, Meek DRM, Patil SR. Obesity is associated with higher complication rates in revision total hip arthroplasty. J Orthop. 2018;15(1):70-2.
Tan TL, Rajeswaran H, Haddad S, Shahi A, Parvizi J. Increased Risk of Periprosthetic Joint Infections in Patients with Hypothyroidism Undergoing Total Joint Arthroplasty. J Arthroplasty. 2016;31(4):868-71.
Lindgren V, Garellick G, Kärrholm J, Wretenberg P. The type of surgical approach influences the risk of revision in total hip arthroplasty: A study from the Swedish Hip Arthroplasty Register of 90,662 total hip replacements with 3 different cemented prostheses. Acta Orthop. 2012;83(6):559-65.
Ilchmann T, Zimmerli W, Bolliger L, Graber P, Clauss M. Risk of infection in primary, elective total hip arthroplasty with direct anterior approach or lateral transgluteal approach: a prospective cohort study of 1104 hips. BMC Musculoskelet Disord. BMC Musculoskeletal Disorders. 2016;17(1):1-6.