2022, Number 3
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Rev Biomed 2022; 33 (3)
Association of sleep disturbances with the development of gestational diabetes mellitus
Valencia-Ortega J, Acosta-Bustos J, Guzmán-Medina DG, Saucedo-García RP
Language: Spanish
References: 70
Page: 114-124
PDF size: 387.27 Kb.
ABSTRACT
Sleeping is a fundamental activity for health, and when alterations
occur, they increase the risk of metabolic, cardiovascular, endocrine
and neurological disorders. Anatomical changes and in respiratory
physiology of pregnancy affect the normal course of sleep, which
in turn affects the health of the pregnant woman so that alterations
in sleep during gestation associate with a greater risk of obstetric
complications, such as gestational diabetes mellitus (GDM). GDM
affects from 4 to 30% of pregnancies in Mexico, and is associated
with short and long term complications for both mother and offspring.
A series of recent studies has offered evidence of a relation between
sleep disorder and the development of GDM, and proposes oxidative
stress, inflammation, activation of the sympathetic nervous system and
hormonal deregulation as underlying mechanisms for said relation.
This underscores the importance of sleep alteration as a modifiable
factor in sight for reduction of the frequency of GDM. The objective
of this manuscript is to carry out a descriptive review about different
studies published from 2013 to 2022, that have addressed the
relationship between sleep disorders and the development of GDM
with emphasis on the proposed mechanisms. The databases used were
PubMed Central and Scielo, using the keywords: sleep disorders and
gestational diabetes mellitus.
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