2021, Number 2
<< Back Next >>
Revista Cubana de Cirugía 2021; 60 (2)
A predictive scale for dehiscence of the Intestinal suture line
Fonseca SFK, Rey VYS, Ramos SAE, Llópiz PRS, Araluce RRA, León FML
Language: Spanish
References: 16
Page: 1-15
PDF size: 456.45 Kb.
ABSTRACT
Introduction:
The suture line dehiscence is one of the most frequent complications in intestinal surgery.
Objective:
To design a predictive scale for estimating individual probability of suture line dehiscence.
Methods:
An analytical cohort study, which involved retrospective data collection, was carried out, in the six-year period of 2014-2019, at Celia Sánchez Manduley Hospital. The sample consisted of 437 patients. Dehiscence of the intestinal suture line was used as a dependent variable, while age, sex, comorbidity, hemoglobin, hypoalbuminemia, colon neoplasia, anesthetic risk, among others, were used as independent variables.
Results:
Through multivariate analysis, an adjusted model was obtained, with the following results for the variables: age over 70 years (P=0.002), hypoalbuminemia (P=0.014), enterocolic anastomosis (P=0.018), urgent surgery (P=0.001), and ileus prolonged paralytic (P<0.001). The predictive scale was derived from the adjusted statistical model and, based on the probability of dehiscence of the intestinal suture line, classified into three risk groups: low (less than two points), moderate (between 3-5 points) and high (more than six points). It presented a sensitivity of 89.6%, a specificity of 89.1%, a global predictive percentage of 89.2%, a positive predictive value of 66.1%, and a negative predictive value of 97.2%. It had an excellent calibration and a high discriminative power.
Conclusion:
A predictive scale was obtained for estimating the individual probability of dehiscence of the intestinal suture line.
REFERENCES
Vicente de la Cruz AA, Concepción de la Peña AH, Hernández-Varea JA. Complicaciones posoperatorias frecuentes. En: Soler R, Mederos ON, editores. Cirugía. Generalidades. La Habana: Ecimed; 2018. p. 355-65.
Diccionario de la lengua española. Dehiscencia. 23.ª edición. Madrid: Espasa Libros; 2014. p. 354.
Vicente Ruiz M. Factores de riesgo de dehiscencia de sutura en cirugía de cáncer de colon [Tesis doctoral]. Región de Murcia: Universidad de Murcia; 2016.
Campos Campos SF, Ureña Álvarez JA, Fuentes Orozco C, Barbosa Camacho FJ, Barrera López FJ, Jiménez Ley VB, et al. Dehiscencia de anastomosis gastrointestinal. Qué hacer y qué no hacer. Cir Gen. 2019;41(4):243-55.
Vandenbroucke JP, Von Elm E, Altman DG, Gøtzsche PC, Mulrow CD , Pocock SJ, et al. Mejorar la comunicación de estudios observacionales en epidemiología (STROBE): explicación y elaboración. Gac Sanit. 2009;23(2):158. DOI: https://doi:10.1016/j.gaceta.2008.12.001
Collins GS, Reitsma JB, Altman DG, Moons KG. Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): The TRIPOD Statement. Ann Intern Med. 2015;162:55-63. DOI: http://doi:10.7326/M14-0697
Fabián Huarcaya K, Huarcaya Mescua CN. Factores determinantes de dehiscencia de anastomosis intestinal en el Hospital Nacional "Ramiro Prialé Prialé" - Huancayo [Tesis de Especialidad]. Perú: Universidad Nacional del Centro de Perú; 2012.
Flores Medina LE. Factores de riesgo asociados a Dehiscencia de Anastomosis posterior a Cirugías Colorrectales en el Hospital Regional Docente de Trujillo [Tesis de Especialidad]. Perú: Universidad Nacional de Trujillo; 2019.
Quintanilla Villanueva CE. Complicaciones asociadas a anastomosis intestinal electiva en pacientes atendidos en el Hospital Escuela Dr. Roberto Calderón Gutiérrez, 2015-2017 [Tesis de Especialidad]. Managua: Universidad Nacional Autónoma de Nicaragua; 2018.
Golda T, Lazzara C, Zerpa C, Sobrino L, Fico V, Kreisler E, et al. Risk factors for ileocolic anastomosis dehiscence; a cohort study. Am J Surg. 2020;220(1):170-77. DOI: https://doi:10.1016/j.amjsurg.2019.11.020
Segelman J, Mattsson I, Jung B, Nilsson PJ, Palmer G, Buchli C, et al. Risk factors for anastomotic leakage following ileosigmoid or ileorectal anastomosis. Colorect Dis. 2018;20(4):304-11.
Jessen M, Nerstrom M, Wilbek TE, Roepstorff S, Rasmussen MS, Krarup PM, et al. Risk factors for clinical anastomotic leakage after right hemicolectomy. Int J Colorectal Dis. 2016;31(9):1619-24. DOI: https://doi.org/10.1007/s00384-016-2623-5
Rodríguez J. Factores de riesgo asociados a fuga anastomótica en pacientes que fueron sometidos a cirugía intestinal atendidos en el Hospital Escuela "Antonio Lenin Fonseca", 2014-2016 [Tesis de Especialidad]. Managua: Universidad Nacional Autónoma de Nicaragua; 2018.
Sakr A, Emile SH, Abdallah E, Thabet W, Khafagy W. Predictive Factors for Small Intestinal and Colonic Anastomotic Leak: a Multivariate Analysis. Indian J Surg. 2017;79(6):555-62. DOI: https://doi.org/10.1007/s12262-016-1556-0
Domenech Pina E, Romero Simo M, Rojas Machado SA, Arroyo Sebastian A, Calpena R. PROCOLE (Prognostic Colorectal Leakage): A New Prognostic Index to Predict the Risk of Anastomotic Leak in Colorectal Cancer Surgery. Clin Gastroenterol J. 2016;1(2):1-5.
Ruiz Hidalgo D. Desarrollo y validación de un modelo predictivo de mortalidad a corto plazo en ancianos ingresados por patología médica [Tesis doctoral]. Barcelona: Universidad Autónoma de Barcelona; 2016.