2022, Number 09
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Ginecol Obstet Mex 2022; 90 (09)
Prenatal exposure to carbon monoxide and particulate matter and its association with preeclampsia in Colombia
Narváez-Enríquez NE, Henao-Navarro LD, Ruiz-Murcia A, Aristizábal-Zuluaga BH
Language: Spanish
References: 20
Page: 715-725
PDF size: 227.71 Kb.
ABSTRACT
Objective: To determine the association between exposure to PM10 and carbon
monoxide vehicle emissions and preeclampsia in Manizales, Colombia.
Materials and Methods: This was a relational, retrospective, case-control study in
patients with pregnancy complicated by preeclampsia, residents of Manizales-Colombia
between July 2014 and July 2015. The place of residence was used to estimate exposure
and the concentration of pollutants through an instrument for determining exposure to
PM10 and CO emissions (tons per year for every 250 square meters). Two definitions
of exposure were used: upper quartile (Q4) vs the remaining quartiles (Q1-Q3) and
another: comparison of the four quartiles taking the first quartile (Q1) as a reference.
Logistic regression models were fitted in order to explore the effect of exposure.
Results: 222 patients were included, 74 cases and 148 controls. No relationship was
observed between the concentration of PM10 in the mother's area of residence and the
probability of presenting preeclampsia with both the first definition of exposure (OR
of 1.013 (95%CI: 0.35 to 2.97) p = 0.981) as with the second (Q2 (p=0.562), Q3 (p =
0.347), Q4 (p = 0.887)). In the case of OC, no statistical relationship was found in the
two definitions (OR: 0.829 (95%CI: 0.29 to 2.39) p = 0.729).
Conclusions: No association was observed between the levels of exposure to
PM10 and CO and the appearance of preeclampsia in pregnant women during the
times described.
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