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2021, Number 1

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Invest Medicoquir 2021; 13 (1)

Multiple Sclerosis and Parkinson's disease

Diaz FA, Peláez SAA, Robinson AMA, Carralero EE, Ugarte MD

Language: Spanish
References: 40
Page:
PDF size: 292.98 Kb.


ABSTRACT

We are presenting the case of a 53 year-old female patient diagnosed with Parkinson's disease in 2003 with good response to treatment during 10 years, but far ahead presented progressive gait instability. (2) Methods: clinically evaluated at the emergency room, including laboratory and MRI studies, the patient was diagnosed as having Multiple Sclerosis (MS). The anti-Parkinson disease drugs were substituted by IV methylprednisolone. (3) Results: patient´s clinical evolution got better on gait stability, but Parkinsonism progressively got worse. Therefore, the diagnoses of both Multiple Sclerosis and Parkinson's disease were established for this patient and the anti-Parkinson treatment was reinstated in, with a favorable response. On consulted literary works, the most common association of Parkinsonism and MS is symptomatic; however, a coincidental relationship between PD and MS is also reported, as in this case. Previous investigations have suggested that both diseases could share common underlying mechanisms, although more evidence must be pointed out to give strong support to this view.


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