2001, Number S1
Myocardial revascularization in patients with acute myocardial infarction complicated by cardiogenic shock
Language: Spanish
References: 13
Page: 54-57
PDF size: 38.74 Kb.
ABSTRACT
In the last 20 years, the acute myocardial infarction 30 day mortality rate has been reduced significantly, following pharmacological and mechanical reperfusion therapies. Nevertheless, cardiogenic shock complicating acute myocardial infarction remains the leading cause of death because of the extensive ventricular function damage non. Randomized studies were overoptimistic reporting markedly lower mortality rates among patients who had undergone revascularization for shock. Further randomised studies showed that the angiographic improvement is not always followed by a significant mortality reduction. However, angiographic study and revascularisation is the treatment of choice. In addition to an early reperfussion, new pharmacological and/or genetic ways to improve the ventricular function have to be found.REFERENCES
TIEFENBRUNN AJ, CHANDRA NC, FRENCH WJ, GORE JM, ROGERS WJ: Clinical experience with primary percutaneous transluminal coronary angioplast, compared with alteplase (recombinant tissue-type plasminogen activator) in patients with acute myocardial infarction: a report from the Second National Registry of Myocardial Infarction (NRMI-2). J Am Coll Cardiol 1998; 31: 1240-5.
HOCHMAN JS, BOLAND J, SLEEPER LA, PORWAY M, BRINKER J, COL J, JACOBS A, SLATER J, MILLER D, WASSERMAN H, MENEGUS MA, TALLEY D, MCKINLAY S, SANBOM T, LeJemtel and the SHOCK Registry Investigators: Current spectrum of cardiogenic shock and effect of early revascularization on mortality. Results of an International registry. Circulation 1995; 91: 873-81.
BERGER PB, HOLMES DR, STEBBINS AL, BATES ER, CALIFF RM, TOPOL EJ, for the GUSTO 1 investigators: Impact of an aggressive invasive catheterization and revascularization strategy on mortality in patients with cardiogenic shock in the Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries (GUSTO 1) trial. An observational study. Circulation 1997; 96: 122-7.
URBAN P, STAUFFER JC, BLEED D, KHATCHATRIAN N, AMANN W, BERTEL O, VAN DEN BRAND M, DANCHIN N, KAUFMANN U, MEIER B, MACHECOURT J, Pfsterer M for the (S)MASH investigators: A randomized evaluation of early revascularization to treat shock complicating acute myocardial infarction. Eur Heart J 1999; 20: 1030-1038.
HOCHMAN JS, BULLER CE, SLEEPER LA, BOLAND J, DZAVIK V, SANBORN TA, GODFEY E, WHITE HD, LIM J, LEJEMTEL T, for the SHOCK investigators: Cardiogenic Shock complicating acute myocardial infarction-Etiologies, management and outcome: A report from the SHOCK trial registry. J Am Coll Cardiol 2000; 36-1063-70