medigraphic.com
ISSN 2007-8013 (Print)
Órgano oficial de la Universidad Autónoma de Sinaloa

2021, Number 1

<< Back Next >>

Rev Med UAS 2021; 11 (1)

Eruptive xanthomas as initial manifestation of dyslipidemia. Case report

Gaxiola-Álvarez EA, Magdaleno-Lomelí CA

Language: Spanish
References: 18
Page: 56-60
PDF size: 138.29 Kb.


ABSTRACT

Eruptive xanthomas are abnormal deposits of lipids in the skin, rare but of great importance due to their growth with serious metabolic disorders such as severe hypertriglyceridemia. They are characterized by the sudden appearance of multiple yellowish papules with erythematous halo, from 1 to 5 mm in diameter in areas of extension of extremities, back and buttocks. The diagnosis is confirmed with histological study by observing the foam cells. Treatment consists of controlling the underlying disease, usually with lipid-lowering agents, hypoglycaemic agents and lifestyle style.
Case Report: We present the clinical case of a 24-year-old female patient with a history of diabetes mellitus, in whom eruptive xanthomas were the first clinical manifestation of a dyslipidemia of which no carrier was known.


REFERENCES

  1. Koh XQ, Chandran NS. Eruptive Xanthomas.J Pediatr. 2018;201:295.

  2. Wanat K, Noe MH. Cutaneous xanthomas.Uptodate. 2017. Disponible en: https://wwwuptodate-com.pbidi.unam.mx:2443/contents/cutaneous-xanthomas?search=xantomas%20eruptivos&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1

  3. Jofre M, Lucía N, Buonsante ME, Abeldaño A.Xantomas eruptivos como manifestación deenfermedades sistémicas. Piel: Formacióncontinua en dermatología.2018;33(9):571-574.

  4. Rojas GA, Hernández DK, Espinoza W. Xantomatosiseruptiva: presentación de un caso yrevisión de la literatura. Revista Colombianade Endocrinología, Diabetes & Metabolismo.2018;5(1):44-46.

  5. Santiago L, Pinho A, Cardoso JC. EruptiveXanthomas: A Cardinal Manifestation of SeriousMetabolic Disease. Acta Med Port.2018;31(4):219-222.

  6. Aldama A, Aquino N. Xantomas eruptivos manifestacióninicial de síndrome metabólico.Tendencias en medicina. 2014;IX(9):88-92.

  7. Wollina U, Koch A, Hansel G, Schonlebe J.Eruptive Xanthomas - Two Case Reports WithDistinct Features. Open Access Maced J MedSci. 2018;6(11):2152-2154.

  8. Vangara SS, Klingbeil KD, Fertig RM, RadickJL. Severe hypertriglyceridemia presenting aseruptive xanthomatosis. J Family Med PrimCare. 2018;7(1):267-270.

  9. Soares LP, Castro Júnior DF, Neves LL,Gratão HS, Rossi AB, Ferreira ACC. Xantomaeruptivo – relato de caso. Revista de Patologiado Tocantins. 2018;5(3):48-51.

  10. Gong Hz, Zheng Y, Li J. Xanthomadisseminatum. The Lancet.2018;391(10117):251.

  11. Khondker L, Huda F. Multiple xanthomas in apatient with hypothyroidism: A case report andreview of literature. The Gulf journal of dermatology& venereology. 2017;24(2):37-46.

  12. SJ D. ERUPTIVE XANTHOMAS-MARKERFOR HYPERTRIGLYCERIDEMIAS.University Journal of Medicine and MedicalSpecialities. 2017;3(4).

  13. Buonuomo PS, Malamisura M, Macchiaiolo M,Rana I, Gonfiantini MV, Mastrogiorgio G, et al.Eruptive Xanthomas in Lipoprotein Lipase Deficiency.J Pediatr. 2017;187:330.

  14. Hanami Y, Yamamoto T. Eruptive xanthomawith isomorphic response of Koebner in aconstruction worker with severe hyperlipidemia.J Dermatol. 2017;44(7):e162-e3.

  15. Scavo S, Magro G, Gurrera A, Gozzo E, IgnaccoloL, Neri S. Isomorphic response in eruptivexanthomas. Dermatology. 2004;209:66–68.

  16. Gao H, Chen J. Eruptive xanthomas presentingin tattoos. CMAJ. 2015;187(5):356.

  17. Miwa N, Kanzaki T. The Koebner phenomenonin eruptive xanthoma. J Dermatol.1992;19:48–50

  18. Barker DJ, Gould DJ. The K€obner phenomenonin eruptive xanthoma. Arch Dermatol 1979;115:112.




2020     |     www.medigraphic.com