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2022, Number 3

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Rev Mex Anest 2022; 45 (3)

Lactate as an early marker of cerebral hypoxia in neurological patients under general anesthesia: a systematic review

Charry-Borrero DA, Tuta-Quintero E, Callejas-Ávila PA, Camilo-Cedeño J, Pinzón A, Reyes-Cruz D, García-Espitia E, Mazzei-Strocchia E, Valencia C, Barahona-Espinosa D, León-Ariza HH, Acosta-Pradilla L, Ríos-Barbosa F, Botero-Rosas DA

Language: Spanish
References: 31
Page: 163-171
PDF size: 341.83 Kb.


ABSTRACT

Perioperative neurological complications secondary to hypoxia during sedation and general anesthesia procedures are frequent in cardiovascular surgery, and in patients with comorbidities. However, so far there is no consensus for the diagnosis of these possible complications. In patients with head trauma severe and/or subarachnoid hemorrhage cerebral lactate was not useful for predicting cerebral hypoxia, however the lactate/pyruvate ratio could be a tool for intraoperative diagnosis of acute cerebral hypoxia. Studies suggest that it must be associated with other markers or multimodal monitoring. Further studies are needed to evaluate lactate predictive value for the diagnosis of cerebral hypoxia.


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