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2021, Number 1

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Rev cubana med 2021; 60 (1)

Efficacy of endobronchial ultrasound with fine needle aspiration in the diagnosis of hilar and mediastinal lesions

Pino APP, Hernández ML

Language: Spanish
References: 23
Page: 1-9
PDF size: 291.56 Kb.


ABSTRACT

Introduction: Linear endobronchial ultrasound with transbronchial fine needle aspiration is a novel technique for the diagnosis of tumors and mediastinal and hilar lymph nodes.
Objective: To evaluate the diagnostic efficacy of linear endobronchial ultrasound with transbronchial fine needle aspiration as a method of studying hila and mediastinal lesions.
Methods: A prospective descriptive study was carried out in 49 patients who underwent linear endobronchial ultrasound with transbronchial fine needle aspiration.
Results: The diagnosis was obtained by histology and 48 patients were positive, 45 of them resulted positive by linear endobronchial ultrasound with transbronchial fine needle aspiration and 4 resulted negative by this study. The overall result of the investigation showed a sensitivity of 93.8%, specificity 100%, a positive predictive value of 100% and a negative predictive value of 25%. Thus, the validity index of linear endobronchial ultrasound with transbronchial fine needle aspiration was 93.8%. The number of complications was minimal.
Conclusions: Linear endobronchial ultrasound with transbronchial fine needle aspiration is an effective and safe diagnostic method in the study of patients with hilar and mediastinal lesions with high suspicion of lung cancer and, consecutively, it is an alternative to access the mediastinum in a non- invasive approach for lymph node staging.


REFERENCES

  1. Fernández-Bussy S, Labarca G, Canals S, Zagollin M, Oyonarte MM, Isamit D, et al. Bronchoscopywith transbronchial biopsy for the diagnosis of potentially malignant pulmonary lesions:experience in 261 patients. Rev Med Chile. 2015[acceso: 10/05/2020];143(4):433-8. Disponible en:https://www.researchgate.net/publication/282187383_Bronchoscopy_with_transbronchial_biopsy_for_the_diagnosis_of_potentially_malignant_pulmonary_lesions_Experience_in_261_patients

  2. Vilmann P, Clementsen PF, Colella S, Siemsen M, De Leyn P, Dumonceau JM, et al. Combinedendobronchial and esophageal endosonography for the diagnosis and staging of lung cancer. TheEuropean respiratory journal. 2015;46(1):40-60.

  3. Costa ADS Jr, Palomino ALM, Suzuki I, Scordamaglio Pr, Gregorio MG, Jacomelli M.Endobronchial ultrasound: a minimally invasive technology to assist diagnosis of thoracic diseases.Publisher: Instituto de Ensino e Pesquisa Albert Einstein. 2019;17(3):2317-63.

  4. Santos RD, Jacomelli M, Franceschini JP, Suzuki I, Costa ADS Jr, Shiang C, et al. Endobronchialultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in diagnosis of mediastinallesions, Publisher: Instituto de Ensino e Pesquisa Albert Einstein. 2018;16(2):40-94.

  5. Aljohaney AA. Utility and safety of endobronchial ultrasound-guided transbronchial needleaspiration in patient with mediastinal and hilar pymphadenopathy: western region experience.Annals Of Thoracic Medicine. 2018;13(2):92-100.

  6. Herth FJ, Eberhardt R, Vilmann P, Krasnik M, Ernst A. Real-time endobronchial ultrasoundguided transbronchial needle aspiration for sampling mediastinal lymph nodes. Thorax.2016;61(1):795-8.

  7. Val-Bernal JF, Martino M, Yilera E, Romay F, Sánchez-Ares M, Nallib IA. Endobronchialultrasound-guided transbronchial needle aspiration in the diagnosis of hilar and mediastinal lymphnode metastases of melanoma. Turk Patoloji Dernegi. 2019;35(2):92-101.

  8. Guarize J, Casiraghi M, Donghi S, Doitti C, Vanoni N, Romano R, et al. Endobronchial UltrasoundTransbronchial Needle Aspiration in Thoracic Diseases: Much More than Mediastinal Staging.Canadian Respiratory Journal. 2018;211(4):582-89.

  9. Andreo García F, Rosell Gratacós A, Monsó Molas E. The Latest in Endobronchial Ultrasound andLung Cancer. Arch Bronconeumol. 2018;54(12):605-6.

  10. Hylton DA, Turner J, Shargall Y, Finley C, Agzarian J, Yasufuku K, et al. Review Lung Cancer.Lung Cancer. 2018;126(6):187-93.

  11. Lin CK, Yu KL, Chang LY, Fan HJ, Wen YF, Ho CC. Differentiating malignant and benign lymphnodes using endobronchial ultrasound elastography. Journal of The Formosan Medical Association.2018;11(6):29-66.

  12. Izumo T, Sasada S, Chavez C. Endobronchial ultrasound elastography in the diagnosis ofmediastinal and hilar lymph nodes. Jpn J Clin Oncol. 2014;44(5):841-5.

  13. Nambirajan A, Longchar M, Madan K, Mallick SR, Kakkar A, Mathur S, et al. Endobronchialultrasound-guided transbronchial needle aspiration cytology in patients with known or suspectedextra-pulmonary malignancies: A cytopathology-based study. Official Journal Of The BritishSociety For Clinical Cytology. 2018;136(5):303.

  14. Argento AC, Gilstrap DL, Shofer S, Mahmood K, Blackwell K, Wahidi MM. Discordance. JournalOf Bronchology & Interventional Pulmonology. 2018;25(3):176-80.

  15. Chazal T, Didier M, Durrleman J, Combes A, Febvre M, Nunes H, et al. Mediastinitis followingendobronchial ultrasound-guided transbronchial needle aspiration. Revue Des MaladiesRespiratoires. 2018;35(7):745-48.

  16. Agrawal SP, Ish P, Goel AD, Gupta N, Chakrabarti S, Bhattacharya D, et al. Diagnostic utility ofendobronchial ultrasound features in differentiating malignant and benign lymph nodes. MonaldiArchives For Chest Disease Archive Monaldi Per Le Malattie Del Torace Monaldi Arch Chest Dis.2018;88(2):928-32.

  17. Bailey N, Krisnadi Z, Kaur R, Mutrennan S, Phillips M, Slavova-Azmanova N. A pragmaticapplication of endobronchial ultrasound-guided transbronchial needle aspiration: a singleinstitution experience. 2019;19(1):155-58.

  18. García Hirschfeld JM, Macías Benítez M, Vicioso Recio L, Arrabal Sánchez R, Jiménez Martín JJ,Sánchez-del Charco M. Validez del diagnóstico citológico de cáncer de pulmón por punciónaspiracióntranstorácica con aguja fina guiada por tomografía computarizada en un hospitalcomarcal. Estudio retrospectivo de 163 casos. Rev Esp Patol. 2017;45(3):163-8.

  19. Navani N, Nankivell M, Lawrence DR, Lock S, Makker H, Baldwin DR, et al. Lung cancerdiagnosis and staging with endobronchial ultrasound-guided transbronchial needle aspirationcompared with conventional approaches: an open-label, pragmatic, randomised controlled trial.The Lancet Respiratory medicine. 2015;342(1):89-92.

  20. Yoon HY, Lee JC, Kim SW, Kim HR, Kim YH, Choi SH, et al. Prognosis of multi-level N2-positivenon-small cell lung cancer according to lymph node staging using endobronchial ultrasoundtransbronchialbiopsy. Thoracic Cancer. 2018(6):684-92.

  21. Vilmann P, Puri R. The complete “medical’’ mediastinoscopy (EUS-FNA + EBUS-TBNA). Minervamedica. 2017;98(4):331-8.

  22. Asano F, Aoe M, Ohsaki Y, Okada Y, Sasada S, Sato S, et al. Complications associated withendobronchial ultrasound-guided transbronchial needle aspiration: a nationwide survey by theJapan Society for Respiratory Endoscopy. Respiratory Research. 2013;14:50-54.

  23. Luque Crespo E. Diagnóstico y estadificación. Técnicas endoscópicas de diagnóstico yestadificación. Broncoscopia, EBUS, EUS. Rev Esp Patol Torac. 2017;29(2):49-57.




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