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Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán

2022, Number 1

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Rev Biomed 2022; 33 (1)

Usefulness of ultrasound versus biopsy in the diagnosis to sentinel node metastasis in patients with breast cancer

Armas M, Brito-Núñez N

Language: Spanish
References: 36
Page: 4-11
PDF size: 116.96 Kb.


ABSTRACT

Introduction. Sentinel lymph node ultrasound can be useful in the early detection of breast metastases.
Objective. To compare the usefulness of ultrasound versus sentinel node biopsy in the diagnosis of sentinel node metastases in patients with breast cancer.
Materials and Methods. A retrospective, observational, descriptive and cross-sectional study was carried out in a group of 148 patients with breast cancer registered in the Venezuelan Anticancer Society January 2018-December 2020.
Results. It was found that the largest number of cases with lymph node metastasis in those older than 40 years (83.1%). Infiltrating ductal carcinoma was the most frequently found entity (83.8% [n = 119]) (p=0.03). The diagnostic concordance of the preoperative ultrasound for the correct diagnosis of a sentinel node was 0.28, which according to the Kappa scale is acceptable (p=0.001). Taking biopsy as gold standard, the correct diagnosis of the sentinel node by ultrasound was 66.4%, 95% confidence interval (95% CI) from 57.7% to 74.2%, the sensitivity was of 47.3% (95% CI, 33.9% -61.1%), the specificity of 79.7% (95% CI, 68.9% -87.5%), the positive predictive value was 61. 9% (95% CI, 45.6% -76.0%) and the negative predictive value was 68.5% (95% CI, 57.8% -77.5%).
Conclusion. Ultrasound has an acceptable utility in the diagnosis of sentinel node metastasis.


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