2020, Number 1
<< Back Next >>
RCU 2020; 9 (1)
Complications of chronic urinary schistosomiasis
Bustamante SN, Bustamante SN, Namugenyi A, Ordaz FY, Lusawana N
Language: Spanish
References: 36
Page: 2-12
PDF size: 817.05 Kb.
ABSTRACT
Introduction: Urinary schistosomiasis is endemic to Southern Africa. In its chronic form, tissue reactions
affect the urinary bladder and the pelvic segments of the ureters. It can cause renal failure, squamous cell
carcinoma, even death. Patients with chronic parasitic lesions were studied.
Objective: To identify chronic complications presented by patients.
Methods: A retrospective study was conducted in eight patients treated for five years due to chronic
complications of the urinary schistosomiasis. The most outstanding parameters were analyzed.
Results: The average age of the patients was 37 years. Males and the age group between 32 and 47 years
were predominant. Gross hematuria and the hypogastrium or lumbar pain prevailed. 75% of the patients
were diagnosed with hydronephrosis, while bilateral ureteral calcifications and bladder calcifications
affected the 33% and 56% of the cases, respectively. All presented vesical parietal thickening. The invasive
squamous cell carcinoma of the bladder was treated in half of the patients. Three total cystectomy with
ileal bypass and four vesicoureteral re-implantations were conducted.
Conclusions: The chronic form of schistosomiasis can be asymptomatic and is uncommon in our hospital.
Urinary tract obstructions cause different degrees of kidney failure, which may improve after surgical
treatment. Patients with bladder´s squamous cell carcinomas attended in advanced stages of the disease
and in all of them was confirmed the presence of urinary schistosomiasis.
REFERENCES
Tan SY, Ahana A. Theodor Bilharz (1825-1862): discoverer of schistosomiasis. Singapore Med J 2007; 48(3):184. Disponible en: http://www.smj.org.sg/sites/default/files/4803 /4803ms1.pdf
Esquistosomiasis. Datos y cifras, 17 de abril de 2019. Disponible en: https://www.who.int/es/news-room/factsheets/ detail/schistosomiasis
World Health Organization (2008) Schistosomiasis: burden and trends. Disponible en: http://www.who.int/bulletin/volumes/86/10/0 8-058669/en/
Naghavi M. Global, regional, and national agesex specific mortality for 264 causes of death, 1980-2016 a systematic analysis for the Global Burden of Disease Study 2016. Lancet 2017; 16(390):1151-210. Disponible en: https://www.thelancet.com
Khalaf I, Shokeir A, Shalaby M. Urologic complications of genitourinary schistosomiasis. World J Urol. 2012 Feb; 30(1):31-8. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/219096 45
Gelfand M. Relation between carcinoma of the bladder and infestation with schistosoma hæmatobium. Lancet. 1967; 289:1249-51.
Palumbo E. Association between schistosomiasis and cancer: A Review. Infect. Dis. Clin. Pract. 2007; 15:145-8.
Organization WH. Evaluation of carcinogenic risk to humans. Schistosomes, liver flukes and Helicobacter pylori. IARC Monogr. 61:45-119. IARC Monogr. 1994; 61.
Biological agents. Volume 100 B. A review of human carcinogens. IARC Monogr. Eval. Carcinog. Risks Hum. 2012; 100:1-441. PMID: 23189750.
World Health Organization. Department of Information, Evidence and Research. April 2018. Estimated deaths ('000) by cause, sex, and Member State 2016. Disponible en: https://www.who.int/healthinfo/global_burden _disease/estimates/en/index1.html
Neal PM. Schistosomiasis an unusual cause of ureteral obstruction, a case history and perspective. Clin Med Res. 2004 Nov; 2(4):216- 27. Disponible en: https://www.ncbi.nlm.nih.gov
Marichal FF, Pérez RP, Peláez RP, Torres PR, Vázquez Drake CT. Esquistosomosis vesical. Reporte de un caso. Archivo Médico Camagüey. 2005; 9(5). Disponible en: http://revistaamc.sld.cu/index.php/amc/article /view/2944/1236
Pazos CP, Pérez de Alejo Alemán A, González González Y. Esquistosomiasis urovesical en Cuba. Detección de un caso en estudiante de Medicina sudafricano. Panorama. Cuba y Salud. 2018 [acceso: 10/05/2018]; 13(1):88-90. Disponible en: http://www.revpanorama.sld.cu/index.php/pa norama/article/view/784
Chávez Troya O, Molina Ramírez B, Rosales Orihuela J. Vejiga de porcelana como consecuencia de esquistosomiasis urinaria. Presentación de un caso clínico con enfoque multidisciplinario. Revista Finlay. 2017 [acceso: 21/10/2017]; 7(1):62-7. Disponible en: http://revfinlay.sld.cu/index.php/finlay/article/ view/463
Fernández LD, Capote RV, del Risco Barrios U. Relación de moluscos dulceacuícolas de relevancia sanitaria para la cayería norte de Camagüey. Estudio preliminar. Revista Archivo Médico de Camagüey. 2015 [acceso: 21/10/2017]; 9(1). Disponible en: http://scielo.sld.cu/pdf/amc/v9n1/amc050105. pdf
Gil RR, de Arriba Muñoz A, del Olmo Izuzquiza IR, Pérez DR, Salas YR, Roldán MJ, Pablo CL. Esquistosomiasis urinaria como causa de macrohematuria. Revista española de pediatría: clínica e investigación. 2010 [acceso: 21/10/2017]; 66(3):171-4. Disponible en: http://www.seinap.es/wpcontent/ uploads/Revistade Pediatria/2010/REP%20663.pdf#page=25
Kayuni S, Lampiao F, Makaula P, Juziwelo L, Lacourse EJ, Reinhard Rupp J, et al. A systematic review with epidemiological update of male genital schistosomiasis (MGS): A call for integrated case management across the health system in sub-Saharan Africa. Parasite Epidemiol Controlv. 2019 Feb.PMC6324017. Disponible en: https://www.ncbi.nlm.nih.gov
Abdel-Naser MB, Altenburg A, Zouboulis CC, Wollina U. Schistosomiasis (bilharziasis) and male infertility. Andrología. 2018; 0(0):e13165. Disponible en: https://www.ncbi.nlm.nih.gov
Abdel-Naser MB, Wollina U, Lohan M, Zouboulis CC, Altenburg A. Schistosomiasis (bilharziasis) ova: an incidental finding in testicular tissue of an obstructive azoospermic man. Andrología. 2018; e13131. Disponible en: https://www.ncbi.nlm.nih.govPbmed/3013628 9
Yirenya Tawiah DR, Ackumey MM, Bosompem KM. Knowledge and awareness of genital involvement and reproductive health consequences of urogenital schistosomiasis in endemic communities in Ghana: a crosssectional study. Reprod. Health. 2016; 13(1):117. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PM C5031356/
Shadab HA, Bronze MS, John JF Jr, Talavera F. Schistosomiasis (Bilharzia). Medscape Updated: Sep 20, 2028. Disponible en: https://emedicine.medscape.com/article/2283 92-overview
Botelho MC, Figueiredo J, Alves H. Bladder cancer and urinary Schistosomiasis in Angola. J Nephrol Res. 2015 Jun; 1(1):22-4. Disponible en: https://www.ncbi.nlm.nih.gov
Jiménez Coronel V, Díaz Rubia L, Martínez Huertas C, Gutiérrez Gallardo M, Dávila Arias C. Manifestaciones radiológicas de la esquistosomiasis. Revisión del tema. Sociedad Española de Radiología Médica. Disponible en: https://piper.espacioseram. com/index.php/seram/article/view/924
Makar N. Urological Aspects of Bilharziasis in Egypt. Societe Orientale de Publicite, 1995, Cairo, p 51. Google Scholar. Disponible en: https://www.cabdirect.org/cabdirect/
Kleppa E, Klinge KF, Galaphaththi-Arachchige HN, Holmen SD, Lillebø K, Onsrud M, et al. Schistosoma haematobium Infection and CD4+ T-Cell Levels: A Cross-Sectional Study of Young South African Women. Published online 2015 Mar 13. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles
Weerakoon KGAD, Gobert GN, Cai P, McManus DP. Advances in the Diagnosis of Human Schistosomiasis Clin Microbiol Rev. 2015 Oct; 28(4): 939-67. Published online 2015 Jul 29. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PM C4548261
El Ochi MR, Oukabli M, Bouaiti E, Chahdi H, Boudhas A. Expression of human epidermal growth factor receptor 2 in bladder urothelial carcinoma. BMC Clinical Pathology (2017)17:3. Disponible en: https://bmcclinpathol.biomedcentral.com/trac k/pdf/10.1186/s12907-017-0046-z
Dessyn JF, Duquenne S, Hoarau G. Incidental pseudolymphomatous bladder inflammatory polyp revealing urinary schistosomiasis. Int J Infect Dis. 2016; 53:39-40. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/278105 20
Diao BL, Amath T, Fall B, Fall PA, Diémé MJ, Steevy NN, et al. Bladder cancers in Senegal: epidemiological, clinical and histological features. Prog Urol. 2008 Jul; 18(7):445-8. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/186026 05
Dematei A, Fernandes R, Soares R, Alves H, Richter J, Botelho MC. Angiogenesis in Schistosoma haematobium-associated urinary bladder cancer. APMIS. 2017 Dec; 125(12):1056- 62. Disponible: https://www.ncbi.nlm.nih.gov/pubmed/289605 60
Rambau PF, Chalya FL, Jackson K. Schistosomiasis and urinary bladder cancer in north western Tanzania: a retrospective review of 185 patients. Infectious Agents and Cancer 2013, 8:19. Disponible en: http://www.infectagentscancer.com/content/8 /1/19
Chang AH, Blackburn BG, Hsieh MH. Tuberculosis and Parasitic Infections of the Genitourinary Tract, 421-446.e5 Part III Chapter 17. Wein AJ, Campbell-Walsh Urology, Eleventh Edition. Philladelphia ISBN: 978-1-4557-7567-5. International Edition ISBN: 978-0-323-34148-6
González Resina R, Sánchez Bernal ML, Pérez Espejo MP, Rodríguez Corchero FJ, Argüelles Salido E, Campoy Martínez P. Carcinoma epidermoide vesical. Revisión de nuestra serie. Urología Oncológica. Arch. Esp. Urol. 2006; 59(8):785-90. Disponible en: https://www.google.com/search?q=Urolog%C3 %ADa+Oncol%C3%B3gica+Arch.+Esp.+Urol.%2C +59%2C+8+(785-790)%2C+2006
Bowa K, Mulele C, Kachimba J, Manda E, Mapulanga V, Mukosai S. A Review of Bladder Cancer in Sub-Saharan Africa: A Different Disease, with a Distinct Presentation, Assessment, and Treatment. Ann Afr Med. 2018 Jul-Sep; 17(3):99-105. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PM C6126046/
Adeloye D, Harhay MO, Ayepola OO, Dos Santos JR, David RA, Ogunlana OO, et al. Estimate of the incidence of bladder cancer in Africa: A systematic review and Bayesian metaanalysis. International Journal of Urology. 2019; 26:102-12. Disponible en: https://onlinelibrary.wiley.com/doi/pdf/10.111 1/iju.13824
Heyns CF, Van der Merwe A. Bladder cancer in Africa. Can J Urol. 2008 Feb; 15(1):3899-908. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/18304401