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Colegio de Medicina Interna de México.

2021, Number 6

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Med Int Mex 2021; 37 (6)

Antimicrobial use and abuse in COVID-19: When is its use justified?

Pérez-Martínez CA, Padilla-Santamaría F, Helguera-León SA, Mejía-Cornejo JJ, Casados-Rodríguez BE, Martínez-Abarca CI, Zamarrón-López ÉI, Pérez-Nieto OR

Language: Spanish
References: 79
Page: 1015-1029
PDF size: 339.35 Kb.


ABSTRACT

The pandemic due to coronavirus disease 2019 (COVID-19) caused by the SARSCoV- 2 virus has created challenges for its diagnosis and treatment. To date, there is no specific antiviral therapy, this situation has pressured the clinician to offer alternative pharmacological therapies whose benefits may be overshadowed by their risks. Since the beginning of the pandemic, the use of empirical antibiotics has become popular in various treatment protocols worldwide, a treatment that is not recommended in national or international guidelines for the management of COVID-19. Current evidence shows a low incidence of bacterial coinfections, even in severe conditions. Administering an antibiotic incorrectly when there is no indication supported by clinical studies is associated with significant deleterious effects, such as increased mortality. Given the similarity of the infectious clinical picture of COVID-19 with an atypical bacterial pneumonia, ruling out an infectious process in a concise and timely manner is of great importance; for this, biochemical and imaging studies can be done, in addition to a good clinical integration of the patient’s signs and symptoms. This review describes the collection of evidence on bacterial coinfections in COVID-19, the prescription of antibiotics in this disease, and the possible consequences.


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