2021, Number 2
<< Back Next >>
Cir Plast 2021; 31 (2)
Marjolin ulcer and squamous cell carcinoma in patient with an antecedent of burns
González-Vargas I, Tamez-Pedroza L, Facio-Treviño JÁ, Pacheco-Molina C, Treviño-García LA, Treviño-Lozano MA, García-Pérez MM
Language: Spanish
References: 13
Page: 72-76
PDF size: 222.69 Kb.
ABSTRACT
Marjolin's ulcer is a chronic lesion that develops some types of cancer, mainly squamous cell and basal cell carcinoma, although other types of cancer have been reported in these chronic lesions associated with burns, trauma, venous ulcers, pressure ulcers and other chronic wounds. We present the case of a 48-year-old patient who came to the plastic surgery and oncological surgery consultation with two ulcerated lesions in the upper left limb and the lower right limb. The patient had an antecedent of burns in the face, neck, and upper and lower extremities when she was five years-old, which were managed with skin grafts. Biopsies of both lesions that reported squamous cell carcinoma were performed. Oncological surgery doctors performed left transradial amputation, wide resection with tumor-free borders in the right thigh and right inguinal lymph node dissection, and plastic surgery doctors covered the right thigh defect with skin graft. She came to the consulting room four months after surgery with a well-healed upper limb wound, a well-integrated thigh skin graft, no evidence of infection, palpable axillary lymphadenopathy and the inguinal region, free of lymphadenopathy.
REFERENCES
Baldursson B, Sigurgeirsson B, Lindelof B. Venous leg ulcers and squamous cell carcinoma: a large-scale epidemiological study. Br J Dermatol 1995; 133 (4): 571-574.
Abdi MA, Yan M, Hanna TP. Systematic Review of Modern Case Series of Squamous Cell Cancer Arising in a Chronic Ulcer (Marjolin's Ulcer) of the Skin. JCO Glob Oncol 2020; (6): 809-818.
Hernández Martín A, Echeverría Iturbe Celina. Carcinoma espinocelular. Piel 2003; 18 (7): 364-376.
Tian J, Zou JP, Xiang XF, Tang JB, Cheng B. Marjolin's ulcer: A case report and literature review. World Acad Sci J 2020; 3 (1): 1-6.
Da Costa JC. III. Carcinomatous Changes in an Area of Chronic Ulceration, or Marjolin's Ulcer. Ann Surg 1903; 37 (4): 496-502.
Hahn SB, Kim DJ, Jeon CH. Clinical study of Marjolin's ulcer. Yonsei Med J 1990; 31 (3): 234-241.
Chalya PL, Mabula JB, Rambau P, Mchembe MD, Kahima KJ, Chandika AB et al. Marjolin's ulcers at a university teaching hospital in Northwestern Tanzania: a retrospective review of 56 cases. World J Surg Oncol 2012; 10 (1): 38.
Iqbal FM, Sinha Y, Jaffe W. Marjolin's ulcer: A rare entity with a call for early diagnosis. BMJ Case Rep 2015; 2015: 10-13.
Ochenduszkiewicz U, Matkowski R, Szynglarewicz B, Kornafel J. Marjolin's ulcer: malignant neoplasm arising in scars. Reports Pract Oncol Radiother 2006; 11 (3): 135-138.
Bozkurt M, Kapi E, Kuvat SV, Ozekinci S. Current concepts in the management of Marjolin's ulcers: outcomes from a standardized treatment protocol in 16 cases. J Burn Care Res 2010; 31 (5): 776-780.
Jiménez HF, González GM, Douriet MFA. Cirugía e injertos autólogos en el tratamiento de la úlcera de Marjolin: informe de un caso. Dermatol Cosmet Med Quir 2014; 12 (2): 114-117.
Di Martino Ortiz B, Riveros R, Martinez Braga G, Medina de Sosa R, Rodríguez Masi M, Knopfelmacher O et al. Marjolin ulcer: a case report. Our Dermatology Online 2014; 5 (1): 51-53.
Pavlovic S, Wiley E, Guzman G, Morris D, Braniecki M. Marjolin ulcer: an overlooked entity. Int Wound J 2011; 8 (4): 419-424.