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Instituto Nacional de Neurología y Neurocirugía

2021, Number 3

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Arch Neurocien 2021; 26 (3)

Foreign accent syndrome in Multiple Sclerosis, review and case presentation

Barriga-Maldonado V, Posadas-Pinto DR, Cruz-Guillermo M, López-Hernández DC, Treviño-Frenk I

Language: Spanish
References: 82
Page: 40-48
PDF size: 482.92 Kb.


ABSTRACT

Introduction. Foreign Accent Syndrome (FAS) is a rare entity. Patients develop changes in rhythm and tone of speech (prosody), perceived as a different accent than their native language. There are three types of FAS: neurogenic, psychogenic and mixed. FAS is rare in MS, and even more so as a first manifestation. Objective. Review of FAS, types, pathophysiology, presentation in MS and evolution. Summary. Cortical lesions in MS are correlated with cognitive impairment, motor disability, psychiatric symptoms, language 3 disorders, speech impairment, and seizures. Most of the published cases of FAS have suffered injury in the dominant hemisphere, in the prerrolandic cortex and adjacent areas, frontal motor association areas, in the putamen, basal ganglia, and theposterior fossa (protuberance, cerebellum). Different etiologieshave been reported, vascular being the most frequent. We present the case of a 44-year-old woman who first manifestation was FAS, previously interpreted as a brain ischemia and finally diagnosed as multiple sclerosis. This case had partial improvement of the symptoms after phonoaudiologic rehabilitation. Conclusions. FAS is rarely observed as an initial presentation of MS debut, as cortical symptoms are atypical relapses. An inflammatory demyelinating cause should be considered in young patients lacking vascular risk factors, and must be supported by complementary neuroimaging studies.


REFERENCES

  1. Liu H-E, Qi P, Liu Y, Liu H-X, Li G. Foreign accent syndrome: two case reports and literature review. Eur Rev Med Pharmacol Sci. 2015; 19(1):81-85. https://www.europeanreview.org/ article/8337

  2. Villaverde González R, Fernández Villalba E, Moreno Escri-bano A, Alías Linares E, García Santos J.M. Síndrome del acento extranjero como primera manifestación de esclerosis múltiple. Rev Neurol. 2003; 36(11):1035-1039. https://neurologia. com/articulo/2002609

  3. Aguiar Rodríguez A, Díaz de la Fe A, Díaz Márquez R, et al. Disprosodia en ataxia. Rev Mex Neuroci. 2007; 8(6):526-530. http:// previous.revmexneurociencia.com/articulo/disprosodia-en-ataxia/

  4. Verhoaeven J, P. Mariën. Neurogenic foreign accent syndrome: Articulatory setting, segments and prosody in a Dutch speake. Journal of Neurolinguistics. 2010; 23, 599–614. https:// openaccess.city.ac.uk/id/eprint/3301

  5. Mariën P, Verhoeven J, Engelborghs S, Rooker S, Pickut BA, De Deyn PP. A role for the cerebellum in motor speech plan-ning: evidence from foreign accent syndrome. Clin Neurol Neurosurg. 2006; 108(5):518-522. doi: 10.1016/j.clineuro.2005.06.006.

  6. Lippert Gruener M, Weinert U, Greisbach T, Wedekind C. Foreign accent syndrome following traumatic brain injury. Brain Inj. 2005; 19(11):955-958. doi: 10.1080/02699050500109506.

  7. Abel T, Hebb A, Silbergeld D. Cortical stimulation mapping in a patient with foreign accent syndrome: case report. Clin Neurol Neurosurg. 2009; 111(1):97-101. doi: 10.1016/j. clineuro.2008.07.014.

  8. Bakker J, Apeldoorn S, Metz L. Foreign Accent Syndrome in a Patient with Multiple Sclerosis. Can J Neurol Sci. 2004; 31: 271- 272. doi: 10.1017/s0317167100053956.

  9. Chanson J, Kremer S, Blanc F, Marescaux C, Namer I, de Seze J. Foreign accent syndrome as a first sign of multiple sclerosis. Mult Scler. 2009;15(9):1123-1125. doi: 10.1177/1352458509106611.

  10. Bhandari H. Trasient foreign accent syndrome. BMJ Case Rep. 2011; 8. doi: 10.1136/bcr.07.2011.4466.

  11. Luzzi S, Viticchi G, Piccirilli M, Fabi K, Pesallaccia M, Bartolini M, et al. Foreign accent syndrome as the initial sign of primary progressive aphasia. J Neurol Neurosurg Psychiatry. 2008; 79(1):79-81. doi: 10.1136/jnnp.2006.113365.

  12. Berthier M, Roé Vellvé N, Moreno Torres I, Falcon C, Thurmhofer Hemsi K, Paredes Pacheco J, et al. Mild Develop-mental Foreign Accent Syndrome and Psychiatric Comorbidity: Altered White Matter Integrity in Speech and Emotion Regula-tion Networks. Front Hum Neurosci. 2016; 10:399. doi: 10.3389/ fnhum.2016.00399.

  13. Laures-Gore J, Henson JC, Weismer G, Rambow M. Two cases of foreign accent syndrome: an acousticphonetic descrip-tion. Clin Linguist Phon. 2006; 20(10):781-790. doi: 10.1080/02699200500391105.

  14. Coelho C, Robb M. Acoustic analysis of foreign accent syndrome: an examination of three explanatory models. Jour-nal of Medical Speech-Language Pathology. 2001; 9(4):227–242. https:// pennstate.pure.elsevier.com/en/publications/acoustic-analysisof- foreign-accent-syndrome-an-examination-of-th

  15. Katz W, Garst D, Levitt J. The role of prosody in a case of foreign accent syndrome (FAS). Clin Linguist Phon. 2008; 22(7):537-66. doi: 10.1080/02699200802106284.

  16. Blumstein S, Alexander M, Ryalls J, et al. On the nature of the foreign accent syndrome: a case study. Brain Lang. 1987; 31(2):215-44. doi: 10.1016/0093-934x(87)90071-x.

  17. Blumstein S, Kurowski K. The foreign accent syndrome: A perspective. Journal of Neurolinguistics. 2006. 19:346-355.https://psycnet.apa. org/doi/10.1016/j.jneuroling.2006.03.003

  18. Aronson A. Dysprosody of pseudo-foreign dialect. In Aronson A (Ed.), Clinical voice disorders. New York: Thieme-Stratton. 1990; 2ed,119- 124. https://doi.org/10.1113/expphysiol.1998.sp004249

  19. Duffy J. Motor speech disorders: Substrates, differential diagnosis, and management, 1st ed. St. Louis, MO: Mosby 1995. https://es.scribd.com/document/501102415/Motor-Speech- Disorders-Substrates-Differential-Diagnosis-And-Managementby- Joseph-R-Duffy

  20. Varley R, Whiteside S. Voicing in severe apraxia of speech: perceptual and acoustic analysis of a single case. J Neurolinguistics. 1998; 11(3): 259-273. https://doi. org/10.1016/S0911-6044(97)00024-9

  21. Whiteside S, Varley R. A reconceptualisation of apraxia of speech: a synthesis of evidence. Cortex. 1998; 34(2):221-31. doi: 10.1016/s0010-9452(08)70749-4.

  22. Varley R, Whiteside S, Luff H. Apraxia of speech as a disruption of word level schemata: some durational evidence. Journal of Medical Speech-Language Pathology. 1999; 7:127–132. https://www. researchgate.net/publication/283833016_Apraxia_of_speech_as_a_ disruption_of_word-level_schemata_Some_durational_evidence

  23. Varley R, Whiteside S, Hammill C., et al. Phases in speech encoding and foreign accent syndrome. J Neurolinguistics. 2006. 19; 356–369. https://doi.org/10.1016/j.jneuroling.2006.03.002

  24. Keulen S, Mariën P, van Dum K, Bastinse R, Manto M, Verhoeven J. The Posterior Fossa and Foreign Accent Syndrome: Report of Two New Cases and Review of the Literature. Cerebellum. 2017; 16(4):772-785. doi: 10.1007/s12311-017-0849-6.

  25. Puthenparampil M, Poggiali D, Causin F, Rolma G, Rinaldi F, Perini P, et al. Cortical relapses in multiple sclerosis. Mult Scler. 2016; 22(9):1184-1191.doi: 10.1177/1352458514564483.

  26. Zarei M. Clinical characteristics of cortical multiple sclerosis. J Neurol Sci. 2006; 15, 245(1-2):53-58. doi: 10.1016/j. jns.2005.08.025.

  27. Lacour A, De Seze J, Revenco E, Lebrun C, Masmoudi K, Vidry E, et al. Acute aphasia in multiple sclerosis: A multicenter study of 22 patients. Neurology. 2004; 23, 62(6):974-977. doi: 10.1212/01.wnl.0000115169.23421.5d.

  28. Renauld S, Mohamed Saïd L, Macoir J. Language disorders in multiple sclerosis: A systematic review. Mult Scler Relat Disord. 2016; 10:103-111. doi: 10.1016/j.msard.2016.09.005.

  29. Lethlean, J.B., Murdoch, B.E. Performance of subjects with multiple sclerosis on tests of high-level language. Ap-hasiology. 1997;11, 39–57. https://doi.org/10.1080/02687039708248454

  30. Blumstein S, Alexander M, Ryalls J, Katz W, Dworetzky B. On the nature of the foreign accent syndrome: a case study. Brain Lang. 1987; 31(2):215-244. doi: 10.1016/0093-934x(87)90071-x.

  31. Schiff H, Alexander M, Naeser M, Galaburda A. Aphemia: clinical – anatomic correlation. Arch Neurol. 1983; 40(12):720- 727. doi: 10.1001/archneur.1983.04050110038005.

  32. Graff Radford N, Cooper W, Colsher P, Damasio A. An unlearned foreign “accent” in a patient with aphasia. Brain Lang. 1986; 28(1):86-94. doi: 10.1016/0093-934x(86)90093-3.

  33. Takayama Y, Sugishita M, Kido T, Ogawa M, Akiguchi I. A case of foreign accent syndrome without aphasia caused by a lesion of the left precentral gyrus. Neurology. 1993; 43(7):1361-1363. doi: 10.1212/wnl.43.7.1361.

  34. Gurd J, Bessell N, Bladon R, Bamford J. A case of foreign accent syndrome, with follow-up clinical, neuropsychological and phonetic descriptions. Neuropsychologia. 1988; 26(2):237- 251. doi: 10.1016/0028-3932(88)90077-2.

  35. González Alvarez J, Parcet Ibars M, Avila C, Geffner Sclarsky D. Una rara alteración del habla de origen neuroló-gico: el síndrome del acento extranjero. Rev Neurol. 2003; 1-15;36(3):227-234. https://neurologia.com/articulo/2002306

  36. Cole M. Dysprosody due to posterior fossa lesions. Trans Am Neurol Assoc. 1971; 96:151-154. https://pubmed.ncbi.nlm. nih.gov/5159072/

  37. Dankovicová J, Hunt C. Perception of foreign accent syn-drome speech and its relation to segmental characteristics. Clin Linguist Phon. 2011; 25(2):85-120. doi: 10.3109/02699206.2010.513027.

  38. Cohen D, Kurowski K, Steven M, Blumstein S, Pascual Leone A. Paradoxical facilitation: the resolution of foreign ac-cent syndrome after cerebellar stroke. Neurology. 2009; 18, 73(7):566-567. doi: 10.1212/WNL.0b013e3181b2a4d8.

  39. Tran A, Mills L. A case of foreign accent syndrome. J Emerg Med. 2013; 45(1):26-29. doi: 10.1016/j.jemermed.2012.11.015.

  40. Mariën P, Verslegers L, Moens M, Dua G, Herregods P, Verhoeven J. Posterior fossa syndrome after cerebellar stroke. Cerebellum. 2013;12(5):686-691. doi: 10.1007/s12311-013-0478-7.

  41. Mariën P, D´aes T. “Brainstem cognitive affective syn-drome” following disruption of the cerebrocerebellar net-work. Cerebellum. 2015; 14(2):221-225. doi: 10.1007/s12311-014-0624-x.

  42. Fink B. Complexity. Science. 1986 Jan 24;231(4736):319. doi: 10.1126/science.231.4736.319-b.

  43. Crosson B. Subcortical functions in language and memory. New York: Guilford Press; 1992.

  44. Fabbro F. The neurolinguistics of bilingualism. An introduction. Hove: Psychology Press; 1999. https://books.google. com.cu/books/about/The_Neurolinguistics_of_Bilingualism. html?id=-HQQNornLNMC&hl=es-419&output=html_text

  45. Murdoch B. Subcortical brain mechanisms in speech and language. Folia Phoniatr Logop. 2001; 53(5):233-251. doi: 10.1159/000052679.

  46. Rosenbek J. Verbal apraxia. In: Fabrro F, Editor. Concise encyclopedia of language pathology. Oxford: Pergamon; 1999. https://doi.org/10.1177%2F13670069000040041001

  47. Tourville J, Guenther F. The DIVA model: A neural theory of speech acquisition and production. Lang Cogn Process. 2011 1; 26(7):952-981. doi: 10.1080/01690960903498424.

  48. Schmahmann J, Pandya D. The cerebrocerebellar system. Int Rev Neurobiol. 1997; 41:31-60. doi: 10.1016/s0074-7742(08)60346-3.

  49. Ayotte J, Peretz I, Hyde K. Congenital amusia: a group study of adults afflicted with a musicspecific disorder. Brain. 2002; 125(2):238-251.

  50. Piccirilli M, Sciarma T, Luzzi S. Modularity of music: evidence from a case of pure amusia. J Neurol Neurosurg Psychiatry. 2000; 69(4):541-545. doi: 10.1093/brain/awf028.

  51. Chiang J, Rosenberg M, Bufford C, Stephens D, Lysy A, Monti M. The language of music: Common neural codes for structured sequences in music and natural language. Brain Lang. 2018;185:30-37. doi: 10.1016/j.bandl.2018.07.003.

  52. Aubé W, Angulo Perkins A, Peretz I, Concha L, Armony J. Fear across the senses: brain responses to music, vocalizations and facial expressions. Soc Cogn Affect Neurosci. 2015; 10(3):399- 407. doi: 10.1093/scan/nsu067.

  53. Angulo Perkins A, Aubé W, Peretz I, Barrios F, Armony J, Concha L. Music listening engages specific cortical regions within the temporal lobes: differences between musicians and non-musicians. Cortex. 2014; 59:126-137. doi: 10.1016/j. cortex.2014.07.013.

  54. Whitehead J, Armony J. Singing in the brain: Neural representation of music and voice as revealed by fMRI. Hum Brain Mapp. 2018; 39(12):4913-4924. doi: 10.1002/hbm.24333.

  55. Karanasios P, Loukopoulou P, Zampakis P, Tiligadas T, Makridou A, Doukas V, et al. Foreign accent syndrome caused by a left temporal-parietal ischaemic stroke. Acta Neuro-psychiatr. 2011; 23(5):249-251. doi: 10.1111/j.1601-5215.2011.00551.x.

  56. Christoph D, de Freitas G, Dos Santos D, Lima M, Araújo A, Carota A. Different perceived foreign accents in one patient after prerolandic hematoma. Eur Neurol. 2004; 52(4):198-201. doi: 10.1159/000082035.

  57. Rovira À, Wattjes M, Tintoré M, Tur C, Yousry T, Sormani M, et al. Evidence-based guidelines: MAGNIMS consensus guidelines on the use of MRI in multiple sclerosis-clinical implementation in the diagnostic process. Nat Rev Neurol. 2015;11(8):471-482. doi: 10.1038/nrneurol.2015.106.

  58. Wattjes M, Rovira À, Miller D, Yousry T, Sormani M, de Stefano M, et al. Evidence-based guidelines: MAGNIMS consensus guidelines on the use of MRI in multiple sclerosis-establishing disease prognosis and monitoring patients. Nat Rev Neurol. 2015;11(10):597-606. doi: 10.1038/nrneurol.2015.157.

  59. Treviño I, Lara J. Resonancia Magnética en Esclerosis múltiple; México, Permanyer. 2017; 79-84

  60. Polman C, Reingold S, Edan G, Filippi M, Hartung H, Kappos L, et al. Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria". Ann Neurol. 2005; 58(6):840-846. doi: 10.1002/ana.20703.

  61. Abdoli M, Chakraborty S, MacLean H, Freedman M. The evaluation of MRI diffusion values of active demyelinating lesions in multiple sclerosis. Mult Scler Relat Disord. 2016; 10:97-102. doi: 10.1016/j.msard.2016.09.006.

  62. Popescu B, Pirko I, Lucchinetti C. Pathology of multiple sclerosis: Where do we stand?. Continuum (Minneap Minn). 2013; 19(4 Multiple Sclerosis):901-921. doi: 10.1212/01. CON.0000433291.23091.65.

  63. Filippi M, Rocca M, Barkhof F, Brück W, Chen J, Comi G, et al. Association between pathological and MRI finding in multiple sclerosis. Lancet Neurol 2012; 11: 349–360. doi: 10.1016/ S1474-4422(12)70003-0.

  64. Calabrese M, Rinaldi F, Grossi P, Gallo P. Cortical pa-thology and cognitive impairment in multiple sclerosis. Expert Rev Neurother. 2011 Mar;11(3):425-432. doi: 10.1586/ern.10.155.

  65. De Santis S, Granberg T, Ouellette R, Treaba C, Qiuyun F, Herranz E, et al. Early axonal damage in normal appearing white matter in multiple sclerosis: Novel insights from multishell diffusion MRI. Conf Proc IEEE Eng Med Biol Soc. 2017; 2017:3024-3027. doi: 10.1109/EMBC.2017.8037494.

  66. Lucchinetti C, Popescu B, Bunyan R, Moll N, Roemer S, Lassmann H, et al. Inflammatory cortical desmyelination in early multiple sclerosis. N Engl J Med. 2011; 8, 365(23):2188-2197. doi: 10.1056/NEJMoa1100648.

  67. Nielsen Lagumersindez D, Wrzos C, Mack M, Winkler A, van der Meer D, Reinert M, et al. Differential contribution of immune effector mechanisms to cortical demyelination in multiple sclerosis. Acta Neuropathol. 2017; 134(1):15-34. doi: 10.1007/s00401-017-1706-x.

  68. Azevedo C, Jaberzadeh A, Pelletier D. New concepts related to disease appreciation in Multiple Sclerosis. Neurol Clin. 2018; 36(1):119-133. doi: 10.1016/j.ncl.2017.08.010.

  69. Peterson J, Bö L, Mörk S, Chang A, Trapp B. Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions. Ann Neurol. 2001; 50(3):389-400. doi: 10.1002/ana.1123.

  70. Wegner C, Esiri M, Chance S, Palace J, Matthews P. Neocortical neuronal, synaptic, and glial loss in multiple sclerosis. Neurology. 2006; 26, 67(6):960-967. doi: 10.1212/01. wnl.0000237551.26858.39.

  71. Klaver R, Popescu V, Voorn P, Galis de Graaf Y, van der Valk P, de Vries H, et al. Neuronal and axonal loss in normalappearing gray matter and subpial lesions in multiple sclerosis. J Neuropathol Exp Neurol. 2015; 74(5):453-458. doi: 10.1097/ NEN.0000000000000189.

  72. Magliozzi R, Howell O, Reeves C, Roncaroli F, Nicholas R, Serafini B, et al. A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis. Ann Neurol. 2010; 68(4):477-493. doi: 10.1002/ana.22230.

  73. Trapp B, Vignos M, Dudman J, Chang A, Fisher E, Staugaitis S, et al. Cortical neuronal densities and cerebral white matter demyelination in multiple sclerosis: a retrospective study. Lancet Neurol. 2018; 17(10):870-884. doi: 10.1016/S1474-4422(18)30245-X.

  74. Roosendaal S, Bendfeldt K, Vrenken H, Polman C, Borgwardt S, Radue E, et al. Grey matter volume in a large cohort of MS patient: Relation to MRI parameters and disability. Mult Scler. 2011; 17(9):1098-1106. doi: 10.1177/1352458511404916.

  75. Hulst H, Steenwijk M, Versteeg A, Pouwels P, Vrenken H, Uitdehaag B, et al. Cognitive impairment in MS: Impact of white matter integrity, gray matter volume and lesions. Neurology. 2013;12,80(11):1025-1032. doi: 10.1212/WNL.0b013e31828726cc.

  76. Demirkiran M, Ozeren A, Sönmezler A, Bozdemir H. Crossed aphasia in multiple sclerosis. Mult Scler. 2006;12(1):116-119. doi: 10.1191/135248506ms1255cr.

  77. Calabrese M, Grossi P, Favaretto A, Romualdi C, Atzori M, Rinaldi F, et al. Cortical pathology in multiple sclerosis patients with epilepsy: A 3-year longitudinal study. J Neurol Neurosurg Psychiatry. 2012; 83(1):49-54. doi: 10.1136/jnnp-2011-300414.

  78. Kidd D, Barkhof F, McConnell R, Algra P, Allen I, Revesz T. Cortical lesions in multiple sclerosis. Brain. 1999;122 (1):17-26. doi: 10.1093/ brain/122.1.17.

  79. Simon B, Schmidt S, Lukas C, Gieseke J, Träber F, Knol D, et al. Improved in vivo detection of cortical lesions in multiple sclerosis using double inversion recovery MR imag-ing at 3 Tesla. Eur Radiol. 2010; 20(7):1675-1683. doi: 10.1007/s00330-009-1705-y.

  80. Filippi M, Rocca M, Calabrese M, Sormani M, Rinaldi F, Perini P, et al. Intracortical lesions: relevance for new MRI diagnostic criteria for multiple sclerosis. Neurology. 2010; 30, 75(22):1988-1994. doi: 10.1212/WNL.0b013e3181ff96f6.

  81. Thompson A, Banwell B, Barkhof F, Carroll W, Coetzee T, Comi G, et al. Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. Lancet Neurol. 2018; 17(2):162-173. doi: 10.1016/S1474-4422(17)30470-2.

  82. Kutzelnigg A, Lucchinetti C, Stadelmann C, Brück W, Rauschka H, Bergmann M, et al. Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain. 2005; 128(Pt 11):2705-2712. doi: 10.1093/brain/awh641.




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