2004, Number s2
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Arch Cardiol Mex 2004; 74 (s2)
Myocardial hypertrophy as an adaptative mechanism and as a pathological process
Guadalajara BJF
Language: Spanish
References: 36
Page: 442-454
PDF size: 257.03 Kb.
ABSTRACT
Myocardial hypertrophy is an adaptative mechanism that allows systolic parietal stress to normalize when the heart has to contract against a higher normal pressure (systolic overload), or the diastolic stress when the normal diastolic volume is higher (diastolic overload). That allows the heart to maintain a normal cardiac waste before such hemodynamic overloads. When neurohumoral mechanisms (adrenergic and renin-angiotensin-aldosterone system) are activated by any reason, myocardial interstice augments its collagen tissue and that causes diastolic dysfunction, myocardial ischemia and cardiac failure.
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