2021, Number 2
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Rev Odotopediatr Latinoam 2021; 11 (2)
Orofacial assessment of children with Prader-Willi Syndrome
Frascino A, Rocha FR, Sakura IS, Passone CBG, Cominato L, Pedroso F, Genovez F, Machado F, Araújo M, Carneiro M, Pedroso NP, Maciel S, Damiani D
Language: Spanish
References: 22
Page: 197-205
PDF size: 431.59 Kb.
ABSTRACT
Aim: To assess the oral health status and craniofacial growth of patients with Prader-Willi Syndrome (PWS), compared to obese non-PWS children controls.
Methods and Result: 40 PWS children and 40 non-PWS obese controls, aged 10.9 years (control: 11.89 years) and BMI 22.72 kg/m
2 (control 36.43 kg/m
2) were selected. The number of teeth, type of dentition, presence of caries, gingival bleeding, malocclusion, plaque accumulation, dental erosion, gingival hyperplasia, and enamel hypoplasia were assessed. Questionnaires assessed oral hygiene habits. Panoramic radiographs assessed craniofacial growth. The study group had a 6.8% lower number of teeth compared to the control group. A statistically significant difference was seen in gingival bleeding, dental erosion and enamel hypoplasia (p=0,009; p=0,02 and p=0,006; respectively). There were no statistically significant differences, it was observed an augmented number of carious lesions and Although a higher prevalence
of carious lesions and dental crowding was observed in PWS children, the difference was not satisctically significant (p=0.35 and p=0.07 respectively). Both groups showed poor dental hygiene. PWS children showed augmented mandibular ramus growth with a statistically significant difference (p=0.03).
Conclusion: PWS children had statically augmented gingival bleeding and enamel hypoplasia than non-PWS obese controls. PWS children may present increased craniofacial vertical growth. Further investigations are needed for this population.
REFERENCES
Griggs JL, Sinnayah P, Mathai ML. Prader-Willi syndrome: From genetics to behaviour, with special focus on appetite treatments. Neurosci Biobehav Rev. 2015;59:155-172.
Gunay-Aygun M, Schwartz S, Heeger S, O’Riordan MA, Cassidy SB. The changing purpose of Prader-Willi syndrome clinical diagnostic criteria and proposed revised criteria. Pediatrics. 2001;108(5):E92.
Giuca MR, Inglese R, Caruso S, Gatto R, Marzo G, Pasini M. Craniofacial morphology in pediatric patients with Prader-Willi syndrome: a retrospective study. Orthod Craniofac Res. 2016;19(4):216-221.
Olczak-Kowalczyk D, Korporowicz E, Gozdowski D, Lecka-Ambroziak A, Szalecki M. Oral findings in children and adolescents with Prader-Willi syndrome. Clin Oral Investig. 2019;23(3):1331-1339.
Bantim YCV, Kussaba ST, de Carvalho GP, Garcia-Junior IR, Roman-Torres CVG. Oral health in patients with Prader-Willi syndrome: current perspectives. Clin Cosmet Investig Dent. 2019;11:163-170.
Saeves R, Espelid I, Storhaug K, Sandvik L, Nordgarden H. Severe tooth wear in Prader-Willi syndrome. A case-control study. BMC Oral Health. 2012;12:12.
Lemos AD, Katz CR, Heimer MV, Rosenblatt A. Mandibular asymmetry: a proposal of radiographic analysis with public domain software. Dental Press J Orthod. 2014;19(3):52-58.
Holm VA, Cassidy SB, Butler MG, Hanchett JM, Greenswag LR, Whitman BY, et al. Prader-Willi syndrome: consensus diagnostic criteria. Pediatrics. 1993;91(2):398-402.
da Silva SN, Gimenez T, Souza RC, Mello-Moura ACV, Raggio DP, Morimoto S, et al. Oral health status of children and young adults with autism spectrum disorders: systematic review and meta-analysis. Int J Paediatr Dent. 2017 Sep;27(5):388-398. doi: 10.1111/ipd.12274. Epub 2016 Oct 31. PMID: 27796062.
Duis J, van Wattum PJ, Scheimann A, Salehi P, Brokamp E, Fairbrother L, et al. A multidisciplinary approach to the clinical management of Prader-Willi syndrome. Mol Genet Genomic Med. 2019 Mar;7(3):e514. doi: 10.1002/mgg3.514.
Guerreiro PO, Garcias Gde L. Diagnóstico das condições de saúde bucal em portadores de paralisia cerebral do município de Pelotas, Rio Grande do Sul, Brasil [Oral health conditions diagnostic in cerebral palsy individuals of Pelotas, Rio Grande do Sul State, Brazil]. Cien Saude Colet. 2009 Sep-Oct;14(5):1939-46. Portuguese. doi: 10.1590/s1413-81232009000500036.
Basha S, Enan ET, Mohamed RN, Ashour AA, Alzahrani FS, Almutairi NE. Association between soft drink consumption, gastric reflux, dental erosion, and obesity among special care children. Spec Care Dentist. 2020;40(1):97-105.
Skeie MS, Raadal M, Strand GV, Espelid I. The relationship between caries in the primary dentition at 5 years of age and permanent dentition at 10 years of age - a longitudinal study. Int J Paediatr Dent. 2006;16(3):152-160.
Flores-Mir C, Korayem M, Heo G, Witmans M, Major MP, Major PW. Craniofacial morphological characteristics in children with obstructive sleep apnea syndrome: a systematic review and meta-analysis. J Am Dent Assoc. 2013;144(3):269-277.
Gillett ES, Perez IA. Disorders of Sleep and Ventilatory Control in Prader-Willi Syndrome. Diseases. 2016;4(3).
Lo ST, Collin PJ, Hokken-Koelega AC. Visual-motor integration in children with Prader-Willi syndrome. J Intellect Disabil Res. 2015;59(9):827-834.
Clairman H, Dettmer E, Buchholz A, Cordeiro K, Ibrahim Q, Maximova K, et al. Pathways to eating in children and adolescents with obesity. Int J Obes (Lond). 2019 Jun;43(6):1193-1201. doi: 10.1038/s41366-018-0271-2. Epub 2018 Dec 19. Erratum in: Int J Obes (Lond). 2019 Mar;43(3):638
Ohrn K, Al-Kahlili B, Huggare J, Forsberg CM, Marcus C, Dahllof G. Craniofacial morphology in obese adolescents. Acta Odontol Scand. 2002;60(4):193-197.
Passone CBG, Pasqualucci PL, Franco RR, Ito SS, Mattar LBF, Koiffmann CP, et al. Prader-Willi syndrome: what is the general pediatrician supposed to do? - A review. Rev Paul Pediatr. 2018;36(3):345-352.
Duis J, van Wattum PJ, Scheimann A, Salehi P, Brokamp E, Fairbrother L, et al. A multidisciplinary approach to the clinical management of Prader-Willi syndrome. Mol Genet Genomic Med. 2019;7(3):e514.
Hedgeman E, Ulrichsen SP, Carter S, Kreher NC, Malobisky KP, Braun MM, et al. Long-term health outcomes in patients with Prader-Willi Syndrome: a nationwide cohort study in Denmark. Int J Obes (Lond). 2017;41(10):1531-1538.
Lindgren AC, Barkeling B, Hagg A, Ritzen EM, Marcus C, Rossner S. Eating behavior in Prader-Willi syndrome, normal weight, and obese control groups. J Pediatr. 2000;137(1):50-55.