<< Back Next >>
Enf Infec Microbiol 2020; 40 (4)
Language: Spanish
References: 28
Page: 136-140
PDF size: 377.05 Kb.
ABSTRACT
Introduction. Sexually transmitted diseases have accompanied humanity for much of its history. Syphilis, previously known as
morbus gallicus, is an example of this type of infectious diseases. During the New Granada period, this disease caused havoc in
the population due to the precarious prevailing health conditions, the scarce knowledge of the disease and its difficulty diagnosis.
Objective. To contextualize a medical prescription for syphilis management dating from the 18
th century in the New Kingdom of
Granada. Analyze its components based on current scientific knowledge, and try to understand the possible phytotherapeutic effects
that could have acted on the manifestation of the disease in the population of the time.
Material and methods. Documentary search in the Historical Archive of the University of La Sabana, where the recipe “gallic
infection” was identified. Databases such as Scopus, Clinical Key, Scielo and Google Scholar were used, with no time limit and with
the following search terms: phytotherapy, plant extracts, therapeutic use,
Smilax, Pimpinella, Lavandula, Senna bicapsularis and
vegetable oils.
Results. The source document was transcribed, finding four phytotherapeutic agents: sarsaparilla (
Smilax aspera), composed of
steroidal saponins, polyphenols and flavonoids, with anti-inflammatory, analgesic, cytotoxic and antioxidant properties; anise (
Pimpinella
anisum), with antibacterial, antifungal, antiviral, antioxidant and analgesic medicinal properties; lavender flowers (Lavandula
stoechas), with antibacterial, antifungal and sedative effects; sem (
Senna bicapsularis) leaves with reported antioxidant and antibacterial
activities.
Conclusion. In light of current evidence, it cannot be concluded that the multiple components of this prescription were effective
for the definitive syphilis treatment. However, analgesic and anti-inflammatory properties are recognized in its components.
REFERENCES
Bloom, D.A., “Hippocrates and urology: the first surgical subspecialty”, Urology, 1997, 50: 157-159.
Iommi Echeverría, V., “Girolamo Fracastoro y la invención de la sífilis”, História, Ciências, (Manguinhos, Río de Janeiro), 2010, 17 (4): 877-884.
Armijo Rojas, R., Epidemiología, t. ii, Buenos Aires, Intermédica, 1976, pp. 289-305.
Schreiber, W. y Mathys, F.K., Infectio. Historia de las enfermedades infecciosas, Basilea, Roche, 1987.
Berdasquera Corcho, D., Lazo Álvarez, M.A., Galindo Santana, B.M. y Gala González, A., “Sífilis: pasado y presente”, Rev Cubana Hig Epidemiol, 2004, 42 (2). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_ arttext&pid=S1561-30032004000200008&lng=es (fecha de consulta: 13 de abril de 2020).
Ros-Vivancos, C., González-Hernández, M., Navarro-Gracia, J.F., Sánchez-Payá, J., González-Torga, A. y Portilla-Sogorb, J., “Evolución del tratamiento de la sífilis a lo largo de la historia”, Rev Esp Quimioter, 2018, 31 (6): 485-492.
Rodríguez Cuenca, J.V., Las enfermedades en las condiciones de vida prehispánica de Colombia, 1ª ed., Bogotá, Guadalupe, 2006.
Baker, B.J. y Armelagos, G.J., “The origin and antiquity of syphilis. Paleopathological diagnosis and interpretation”, Current Anthropology, 1998, 29 (5): 720.
Almady Sánchez, E.G., “Sífilis venérea: realidad patológica, discurso médico y construcción social. Siglo xvi”, Cuicuilco 2010, 17 (49): 183-197.
Guzmán Urrego, M.A., Sífilis: diagnóstico y manejo serológico, 3ª ed., Bogotá, Instituto Nacional de Salud, 1983.
Tampa, M., Sarbu, I., Matei, C., Benea, V. y Georgescu, S.R., “Brief history of syphilis”, J Med Life, 2014, 7 (1): 4-10.
Volcy, C., “Sífilis: neologismos, impacto social y desarrollo de la investigación de su naturaleza y etiología”, Iatreia, 2014, 27 (1) :99-109.
Obregón, D., “Médicos, prostitución y enfermedades venéreas en Colombia (1886-1951)”, Hist Cienc, Saúde (Manguinhos) 2002, 9 (suppl): 161-186. Disponible en: https://doi.org/10.1590/S0104-59702002000400008.
Elting, J.J. y Starna, W.A., “A possible case of pre-columbian treponematosis from New York State”, Am J Phys Anthrop, 1984, 65: 267-273.
Rodríguez, J.V. y Rodríguez, C., “Bioantropología de los restos óseos provenientes de un sitio tardío en el bajo Río Magdalena (El Salado, Salamina, Magdalena)”, Revista Maguaré, 2002, 15-16: 187-234.
Rodríguez, J.V., Rodríguez C.A. y Bernal, F., “Dos posibles casos de treponematosis en restos prehispánicos del Valle del Cauca, Colombia”, Revista Maguaré, 1998, 13: 85-98.
Rehman, S.U., Choe, K. y Yoo, H.H., “Review on a traditional herbal medicine, eurycoma longifolia Jack (Tongkat Ali): its traditional uses, chemistry, evidence-based pharmacology and toxicology”, Molecules, 2016, 21 (3): 331.
Duraz, A.Y. y Khan, S.A., “Knowledge, attitudes and awareness of community pharmacists towards the use of herbal medicines in Muscat region”, Oman Med J, 2011, 26 (6): 451-453.
Pita Pico, R., “Las boticas en el Nuevo Reino de Granada a finales del periodo colonial: el lento camino hacia la modernidad”, Medicina”, 2015, 37: 223-241.
Murray, M., “Sarsaparilla species”, Natural medicine, 4ª ed., Elsevier, 2013, pp. 1018-1020. Disponible en: https:// www-clinicalkey-es.ez.unisabana.edu.co/service/content/ pdf/watermarked/3-s2.0-B9781437723335001218. pdf?locale=es_ES&searchIndex= (fecha de consulta: 18 de abril de 1010).
Khan, A., Singh, P.D., Reese, P.B., Howden, J., Golding, M. y Thomas, T.T., “Investigation of the preliminary mechanism of action for the acute anti-inflammatory activity of the methanol extract of Smilax ornata lem”, J Ethnopharmacol, 2020, 248: 112360. doi: 10.1016/j. jep.2019.112360.
Picon, P.D., Picon, R.V., Costa, A.F., Sander, G.B., Amaral, K.M., Aboy, A.L. y Henriques, A.T., “Randomized clinical trial of a phytotherapic compound containing Pimpinella anisum, Foeniculum vulgare, Sambucus nigra, and Cassia augustifolia for chronic constipation”, bmc Complement Altern Med, 2010, 10: 17. doi: 10.1186/1472-6882-10-17.
Nahidi, F., Kariman, N., Simbar, M. y Mojab, F., “The study on the effects of Pimpinella anisum on relief and recurrence of menopausal hot flashes”, Iran J Pharm Res, 2012, 11 (4): 1079-1085.
Mosavat, S.H., Jaberi, A.R., Sobhani, Z., Mosaffa-Jahromi, M., Iraji, A. y Moayedfard, A., “Efficacy of anise (Pimpinella anisum L.) oil for migraine headache: a pilot randomized placebo-controlled clinical trial”, J Ethnopharmacol, 2019, 236: 155-160.
Vakilian, K., Atarha, M., Bekhradi, R. y Chaman, R., “Healing advantages of lavender essential oil during episiotomy recovery: a clinical trial”, Complement Ther Clin Pract, 2011, 17 (1): 50-53. doi: 10.1016/j.ctcp.2010.05.006.
Eftekharsadat, B., Roomizadeh, P., Torabi, S., Heshmati- Afshar, F., Jahanjoo, F. y Babaei-Ghazani, A., “Effectiveness of Lavendula stoechas essential oil in treatment of mild to moderate carpal tunnel syndrome: a randomized controlled trial”, J Hand Ther, 2018, 31 (4): 437-442.
Mak, Y.W., Chuah, L.O. y Rajeev Bhat, R.A., “Antioxidant and antibacterial activities of hibiscus (Hibiscus rosa-sinensis L.) and Cassia (Senna bicapsularis L.) flower extracts”, Science (J King Saud University), 2013, 25: 275-282.
Verpoorte, R., Van der Heijden, R. y Memelink, J., “Engineering the plant cell factory for secondary metabolite production”, Transgenic Res, 2000, 9: 323-343.