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Órgano Oficial del Colegio Mexicano de Alergia, Asma e Inmunología Pediátrica y de la Asociación Latinoamericana de Pediatría

2021, Number 2

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Alerg Asma Inmunol Pediatr 2021; 30 (2)

Kawasaki disease, cases diagnosed in two pediatric hospitals in Mexico from January 2004 to March 2020

García-Domínguez M, Quibrera J, Canizales-Muñoz S, López-Nogueda M, León-Ramírez ÁR, Velázquez-Ríos CA, Carreón-Guerrero JM, Llausás-Magaña E, Pérez-Pico VM, Llausas-Vargas A

Language: Spanish
References: 18
Page: 37-42
PDF size: 177.79 Kb.


ABSTRACT

Introduction: Kawasaki disease (KD) is a small and medium vessel vasculitis, that mainly affects patients under 5 years age, of unknown etiology, characterized by an acute febrile syndrome with mucocutaneous manifestations and develop coronary artery abnormalities (CAA). Treatment with Intravenous immunoglobulin (IVIG) and aspirin prevent to CAA and other complications. Objective: To known the epidemiological, clinical characteristics, treatment and complications of KD in two pediatric centers in the northwest of the Mexico in the course of 16 years. Material and methods: Retrospective study of patients with KD in two pediatric centers. The frecuency of patients with a diagnosis of complete and incomplete KD was obtained. The results were represented as mean, standard desviation and median, according to corresponding variable. Results: We report 62 patients with KD. Males were 64.5%, the median age at the time of diagnosis were 33.4 months. Predominant clinical manifestations were fever, rash and conjunctivitis in more than 86% of cases. Incomplete KD were 24%. CAA ocurred in 29% of cases. Anemia, and elevated C-reactive protein (CRP) and erythrocyte sedimentation (ESR) were biomarkers relevant. All recived IVIG, the resistance to IVIG were 19% and there were no deaths. Conclusions: KD has been increasing in recent years of Mexico, being important to known the epidemiological, clinical, treatment and complications. The emergence of COVID-19 pandemic, an increased in KD cases and like-KD, known as multisystem inflammatory syndrome in children associated of SARS-CoV-2.


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