Espinosa SMC, Almonte DAE, Juárez JCA, Reyes GU, De Lara HJ, Quero HA

Language: Spanish
References: 20
Page: 108-112
PDF size: 215.79 Kb.

ABSTRACT

Introduction. The rhinocerebral entomophthoromycosis is clinically characterized by affection in facial subcutaneous tissues, with capacity of invasiveness to deeper tissues, however, it presentation and severity depends of etiological agent.
Description of the case. A 9-year-old female patient, resident of Mexico City with a history of swimming in thermal waters. She begins with right pelvic member clonic seizures with three to four convulsive events per day, increasing in the following days up to 15-20 convulsive seizures. Magnetic resonance imaging reported cerebral edema and leptomeningeal thickening, as well as infectious sinus and mastoid processes. The biopsy and culture was decided and the results correspond to Conidiobolus incongruus. Treatment was started with liposomal amphotericin and itraconazole, with clinical improvement and partial recovery of their functions.
Conclusions. Rhinocerebral entomophthoromycosis due to C. incongruus is an infrequent subcutaneous mycosis and very rare in a pediatric patient. Although the fungus expresses low virulence for humans, it occurs in immunocompetent people. The rarity of the etiological agent and its invasiveness make it difficult to elaborate studies in order to establish an effective treatment.

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