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ISSN 2448-8011 (Electronic)
Revista de Divulgación del INSTITUTO DE MEDICINA FORENSE de la UNIVERSIDAD VERACRUZANA

2021, Number 2

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Rev Mex Med Forense 2021; 6 (2)

Efficiency of five X-STR markers for forensic identification in a western Mexican mestizo population

Medina-Mora Y, Javalera-Castro D, Rivas F, Valle Y, Del Toro-Arreola A, Daneri-Navarro A, Topete A, Padilla-Gutiérrez JR, Quintero-Ramos A

Language: Spanish
References: 44
Page: 38-58
PDF size: 438.96 Kb.


ABSTRACT

Introduction: The short tandem repeats of the X chromosome (X-STR) are useful in forensic identification and kinship testing. There are currently several studies on X-STR; however the panel includes several markers from the same linkage group. By including markers from different linkage group, the test is more efficient. Objective: To establish a panel of five X-STR loci, for application in forensic genetic studies in mestizo population of Western Mexico. Methodology: Five X-STR loci were typed in samples of 379 unrelated individuals from Western Mexico by PCR, 7% polyacrylamide gels and silver staining. Allelic and haplotypic frequencies were estimated, as well as forensic parameters. Results: The combined data showed a discrimination power of 0.999389 and 0.999995 in men and women respectively. The combined mean probability of exclusion was 0.998797 for trio and 0.990701 for duo cases. Discussion: Various reports, which use the Decaplex system, obtain discrimination values in women of 99.9999% and in men of 99.9998%, results very close to ours and with only using five markers. Conclusion: The five X-STR loci analyzed are highly informative for use in forensic issues.


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