2021, Number 2
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Rev Cent Dermatol Pascua 2021; 30 (2)
Cutaneous sinus histiocytosis. Clinicopathological study of 33 patients at the Centro Dermatólogico Pascua
Navarrete FG, Ramos GJA, González GM, Laguna MJP, Domínguez UMG
Language: Spanish
References: 29
Page: 61-67
PDF size: 630.67 Kb.
ABSTRACT
Introduction: Cutaneous sinus histiocytosis (CSH) is a clinical form of Rosai-Dorfman disease or sinus histiocytosis with massive lymphadenopathy (SHLM), this variety limited to the skin is considered rare.
Objective: To know the epidemiology and clinical-pathological characteristics of this entity in the Centro Dermatológico "Dr. Ladislao de la Pascua" (CDP) in Mexico City.
Material and methods: A retrospective, cross-sectional, descriptive and observational study was performed with the records of the CDP Dermatopathology department in 34 years (1985-2019). Cases with histological diagnosis of sinus histiocytosis and only cutaneous disease (by clinical data) where selected.
Results: A total of 33 cases were found, the female gender predominated in 24; the age was between nine and 90 years, with a median of 36. The most frequent location was the face, the clinical aspect was diverse; most cases were chronic and with an asymptomatic evolution. Histologically, the image was characteristic, emperipolesis was observed in all cases.
Conclusions: Cutaneous sinus histiocytosis (CSH) is not as rare as was previously thought, we consider that its recently increase in diagnosis relies on greater clinical and histological knowledge of this disease, hence our interest in communicating this series of cases.
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