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Colegio de Medicina Interna de México.

2021, Number 4

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Med Int Mex 2021; 37 (4)

Clinical characteristics of type 2 diabetic patients with severe hypoglycemia from a Venezuelan hospital

Salazar-Vilchez J, Carbonell Y, Briceño S, Borges I, Añez R

Language: Spanish
References: 21
Page: 506-519
PDF size: 265.31 Kb.


ABSTRACT

Objective: To characterize the factors associated with severe hypoglycemia in patients with type 2 diabetes mellitus.
Materials and Methods: A descriptive, cross-sectional, non-experimental investigation was carried out with a probabilistic sampling in type 2 diabetic patients with severe hypoglycaemia diagnosis, admitted to the internal medicine service of the Hospital General del Sur from Maracaibo city, Venezuela, from December 2017 to July 2018. A questionnaire to identify the potential sociodemographic, clinical or pharmacological factors involved, nutritional, clinical, pharmacological triggering causes and in-hospital complications presented during its management was used.
Results: Of the 106 patients with hypoglycaemia, 51.9% were women and the overall age was 66.5 ± 10 years; 91.5% received monotherapy as antidiabetic treatment, being the sulfonylureas the most frequent with 84% especially glibenclamide. The recent omission of food was the triggering cause with the highest percentage (65.1%) and hypoglycemic encephalopathy the most prevalent acute complication (16%), evidencing up to 15.1% general mortality. The main factors associated with in-hospital complications were the presence of comorbidities (p ‹ 0.01) and with mortality, acute complications (p ‹ 0.01).
Conclusions: There is a high prevalence of severe hypoglycemia in patients with type 2 diabetes mellitus, sulfonylureas are the main conditioning factor and other characteristics that indicate lack of individualization of therapeutic management in these patients.


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