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2020, Número 2

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Invest Medicoquir 2020; 12 (2)


Mitos y realidades sobre el comportamiento del ácido láctico en pacientes sometidos a circulación extracorpórea

Miguel VY, Alvarez PA, De Zayas GJ, Leiva TJL

Idioma: Español
Referencias bibliográficas: 41
Paginas:
Archivo PDF: 496.54 Kb.


RESUMEN

La interpretación, análisis y estrategias del manejo del ácido láctico en los pacientes sometidos a cirugía cardiaca con Circulación Extracorpórea durante los últimos años, han variado. Con el advenimiento de nuevas tecnologías de medición y la comprensión profunda del metabolismo de los carbohidratos en los seres humanos ha hecho que esta molécula, pase de solo ser un villano a una fuente alternativa de energía en momentos fisiológicos especiales, uno de ellos es la Circulación Extracorpórea, en donde la respuesta neuroendocrina al estrés y la respuesta inflamatoria al contacto de una superficie no endotelializada biológicamente, hacen que las respuestas y manifestaciones bioquímicas no estén del todo comprendidas. La molécula del lactato y su incremento en Circulación Extracorpórea, no escapa a esta respuesta; su presentación bimodal y su normalización a corto plazo, han generado manejos y aproximaciones muchas veces erróneas por parte de los especialistas que intervienen en el proceso perioperatorio del paciente sometido a Circulación Extracorpórea. El objetivo de esta revisión es aclarar los mitos y mostrar los hechos reales a la luz del conocimiento actual.


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