2004, Número s2
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Arch Cardiol Mex 2004; 74 (s2)
Inhibidor de las glicoproteínas IIb/IIIa en el infarto al miocardio
Chatterjee K, Gallo E
Idioma: Ingles.
Referencias bibliográficas: 10
Paginas: 148-151
Archivo PDF: 65.91 Kb.
RESUMEN
Los inhibidores de la glicoproteína IIb/IIIa son poderosos agentes antiagregantes plaquetarios y han demostrado gran utilidad en el manejo farmacológico de pacientes con síndrome coronario agudo. Existen varios compuestos de este grupo, en uso actualmente: un anticuerpo monoclonal (abciximab), dos antagonistas no peptídicos del receptor GP IIa/IIIb (tirofiban y lamifiban) y un antagonista peptídico (epitifibatide). Estos compuestos presentan entre sí importantes diferencias farmacocinéticas. Por lo tanto los riesgos y beneficios de su uso deben considerarse en función del perfil clínico de cada paciente.
REFERENCIAS (EN ESTE ARTÍCULO)
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