2020, Número S2
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Rev Mex Traspl 2020; 9 (S2)
Enfermedad hepática y trasplante durante la pandemia COVID-19/SARS-CoV-2
Leal-Leyte P, Zamora-Valdés D, Méndez-Sánchez N
Idioma: Español
Referencias bibliográficas: 78
Paginas: 206-215
Archivo PDF: 278.65 Kb.
RESUMEN
Introducción: La pandemia por SARS-CoV-2/COVID-19 ha afectado todas las áreas de la atención médica, particularmente la atención de enfermedades crónicas. La enfermedad hepática crónica es altamente prevalente en nuestro país y representa una de las principales causas de mortalidad general.
Objetivo: En esta revisión, analizamos la literatura disponible hasta el 5 de junio de 2020 sobre el impacto de SARS-CoV-2/COVID-19 en enfermedades hepáticas y en la actividad de trasplante hepático.
Material y métodos: Realizamos una búsqueda en PubMed con los términos «
liver» (hígado), «
hepatic» (hepático), o «
transplant» (trasplante) y «COVID-19» o «SARS-CoV-2» contenidos en el título o el resumen de la categoría «
Journal Articles» durante el último año. Los artículos fueron analizados por dos revisores de forma independiente.
Resultados: Encontramos 276 resultados, de los cuales 54 artículos cumplieron con los criterios de inclusión. La mayor parte de la información disponible proviene de recomendaciones de expertos o consensos. Los organismos reguladores de donación y trasplante han desarrollado algoritmos específicos para su región con el objetivo de guiar la actividad de trasplantes durante la pandemia. Los programas, en general, han reportado disminución en sus actividades. Los resultados de infección por SARS-CoV-2 en receptores de trasplante hepático no son concluyentes y la evaluación del donante para la infección es ampliamente recomendada.
Conclusión: La pandemia por SARS-CoV-2/COVID-19 ha modificado las prácticas de todos los programas de trasplante alrededor del mundo. La comunidad de trasplantes se encuentra frente a un escenario difícil con evidencia científica escasa que guíe la toma de decisiones sobre el futuro y la atención óptima de pacientes con enfermedad hepática terminal en necesidad de trasplante, durante y después de la pandemia.
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