medigraphic.com
ISSN 2992-779X (Digital)
ISSN 2007-6452 (Impreso)

2018, Número 1

<< Anterior

Investigación en Discapacidad 2018; 7 (1)


Ablación térmica: una alternativa para el cáncer óseo

Trujillo-Romero CJ, Rico-Martínez G, Gutiérrez-Martínez J

Idioma: Español
Referencias bibliográficas: 90
Paginas: 35-46
Archivo PDF: 897.81 Kb.


RESUMEN

El presente trabajo muestra una revisión bibliográfica sobre las terapias más comunes para tratar, de manera general, tumores óseos (cirugía, radioterapia y quimioterapia). Se presenta un análisis de sus principales ventajas, desventajas, efectos secundarios y costos. De igual forma, se hace una exploración profunda de las nuevas técnicas de tratamiento denominadas termoterapias (específicamente la ablación). El objetivo es definir, debido a sus características, si la ablación térmica puede ser considerada abiertamente como una alternativa más para tratar tumores óseos, o incluso si ésta podría llegar a ser una mejor opción que las terapias convencionales. Algunos estudios clínicos y análisis mediante el modelado han demostrado que la ablación térmica (temperaturas ›70°C en el tejido tumoral) es una técnica que presenta resultados satisfactorios al tratar tumores óseos. Existen estudios que demuestran que la ablación térmica es de especial utilidad en la metástasis ósea, ya que disminuye considerablemente el dolor que sienten los pacientes debido a dicho padecimiento. El modelado que aquí se presenta, pretende mostrar, de una manera sencilla, los resultados que se podrían tener al utilizar microondas en el tratamiento de tumores óseos.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. Vernon CC, Hand JW, Field SB, Machin D, Whaley JB. Radiotherapy with or without hyperthermia in the treatment of superficial localized breast cancer: results from five randomized controlled trials. Int J Radiat Oncol BiolPhys. 1996;35(4):731-744.

  2. Linthorst M, Drizdal T, Joosten H, van Rhoon GC, van der Zee J. Procedure for creating a three-dimensional (3D) model for superficial hyperthermia treatment planning. Strahlenther Onkol. 2011;187(12):835-841.

  3. Scott SJ, Prakash P, Salgaonkar V, et al. Approaches for modelling interstitial ultasound ablation of tumours within or adjacent to bone : Theoretical and experimental evaluations. Int J Hyperthermia. 2013 ;6736(7):629-642.

  4. Ruiz Santiago M, Castellano García M, Martınez Montes JL, Trista Fernández JM. Treatment of bone tumours by radiofrequency thermal ablation. Curr Rev Musculoskelet Med. 2009;2:43-50.

  5. American Cancer Society. Treating Bone Cancer. https://www.cancer.org/cancer/bone-cancer/treating.html. Published 2017.

  6. Habash RWY, Bansal R, Krewski D, Alhafid HT. Thermal therapy, part 2: hyperthermia techniques. Crit Rev Biomed Eng. 2006;34(6):491-542.

  7. Hernández AV, Enrique J, Quero C, Salas LL, Marchal C. Hipertermia electromagnética, una alternativa para el tratamiento del cáncer: antecedentes, aspectos físicos y biológicos. 2001; XXII:78-88.

  8. Habash RWY, Bansal R, Krewski D, Ha T. Thermal Therapy , Part III : Ablation. Crit Rev Biomed Eng. 2007;35:37-121.

  9. Simon CJ, Dupuy DE, William W. Microwave Ablation: Principles and Applications. Radiographics. 2005; 25:69-84.

  10. Martínez GR, Cedillo ED, Villaseñor EE, Guzmán RG, Pineda NF. Los dilemas en tumores óseos. Acta Ortopédica Mex. 2007;21(6):349-353.

  11. Olszta MJ, Cheng X, Soo S, et al. Bone structure and formation : A new perspective. Mater Sci Eng R. 2007:1-40. doi:10.1016/j.mser.2007.05.001.

  12. Artner J. Atlas of Human Skeletal Anatomy.; 2002.

  13. Wojnar R. Bone and Cartilage – Its Structure and Physical Properties. (Ochsner A, Ahmed W, eds.).; 2010.

  14. 14.American Cancer Society. Guía Detallada del Cáncer de Hueso. http://www.cancer.org/espanol/cancer /cancerdehuesos/index. Published 2015. Accessed October 26, 2016.

  15. aecc contra el Cáncer. Tratamiento quirúrgico. https://www.aecc.es/SobreElCancer/CancerPorLocalizacion/cancerdeovario/Paginas/tratamientoquirurgico.aspx. Published 2017.

  16. Han W, Yu KN. Response of Cells to Ionizing Radiation. In: S.C.Tjong, ed. Advances in Biomedical Sciences and Engineering. Bentham Science; 2009:320.

  17. Koizumi M, Inoue T, Yamazaki H, et al. Perioperative fractionated high-dose rate brachytherapy for malignant bone and soft tissue tumors. Int J Radiat Oncol Biol Phys. 1999;43(5):989-993.

  18. Gok B, McGirt MJ, Sciubba DM, et al. Adjuvant treatment with locally delivered oncogel delays the onset of paresis after surgical resection of experimental spinal column metastasis. Neuro- surgery. 2009;65(1):193-199.

  19. Spine N, Scale KP, Evaluation R, et al. A preliminary comparative clinical study of vertebroplasty with multineedle od single-needle interstitial implantation of 125I seeds in the treatment of osteolytic metastatic vertebral tumors. J Neurosurg Spine. 2014;20(April): 430-435.

  20. Feng S, Wang L, Xiao Z, et al. 125I Seed Implant Brachytherapy for Painful Bone Metastases After Failure of External Beam Radiation Therapy. Medicine (Baltimore). 2015;94(31):e1253.

  21. Humm JL, Sartor O, Parker C, Bruland OS, Macklis R. Radium-223 in the Treatment of Osteoblastic Metastases: A Critical Clinical Review. Int J Radiat Oncol. 2015;91(5):898-906.

  22. Rosenberg I. Radiation Oncology Physics: A Handbook for Teachers and Students. Int At Energy Agency. 2005;98(5):1020.

  23. Ballester, F. Udías J. Física Nuclear y Medicina. Rev Española Física. 2008;22(1):29-36.

  24. Antonio M, Bracamontes M, José J. Metodología para la selección de una máquina de megavoltaje para el servicio de radioterapia en un hospital del sector salud. Rev Ing Eléctrica, Eléctronica y Comput. 2008;4(1):25-29.

  25. American Cancer Society. Chemotherapy Drugs : How They Work. Am Cancer Soc. 2015:17.

  26. Kashima TG, Gamage NG, Dirksen U, Gibbons CL, Ostlere SJ, Athanasou N a. Localized Ewing sarcoma of the tibia. Clin Sarcoma Res. 2013;3(1):2.

  27. van der Zee J, González González D, van Rhoon GC, van Dijk JD, van Putten WL, Hart a a. Comparison of radiotherapy alone with radiotherapy plus hyperthermia in locally advanced pelvic tumours: a prospective, randomised, multicentre trial. Dutch Deep Hyperthermia Group. Lancet. 2000;355 (9210):1119-1125.

  28. Gautherie DM, ed. Whole Body Hyperthermia: Biological and Clinical Aspects. Springer Berlin Heidelberg; 1992..

  29. Szasz A, Iluri N, Szasz O. Local Hyperthermia in Oncology – To Choose or not to Choose ? In: Hyperthermia. ; 2013:1-82.

  30. van der Zee J. Heating the patient: a promising approach? Ann Oncol. 2002;13(8):1173-1184.

  31. Beck M, Ghadjar P, Weihrauch M, et al. Regional hyperthermia of the abdomen, a pilot study towards the treatment of peritoneal carcinomatosis. Radiat Oncol. 2015;10(1):157.

  32. Hasgall P, Neufeld E, Gosselin M, Klingenbock A, Kuster N. IT’IS database for thermal and electro- magnetic parameters of biological tissues. http://www. itis.ethz.ch/itis-for-health/tissue-properties/overview/. Published 2012.

  33. Van Der Zee J, De Bruijne M, Mens JWM, et al. Reirradiation combined with hyperthermia in breast cancer recurrences: overview of experience in Erasmus MC. Int J Hyperth. 2010;26(7):638-648.

  34. Van Der Zee J, Rietveld PJ. M, Broekmeyer-Reurink MP, Wielheesen D. HM, van Rhoon GC. Hyperthermia in recurrent breast cancer: from experimental oncology to standard practice. Exp Oncol. 2002;2002(24):45-50.

  35. 35.Dupuy DE, Goldberg SN. Image-guided radiofreque- ncy tumor ablation: challenges and opportunities--part II. J Vasc Interv Radiol. 2001;12(10):1135-1148.

  36. Gebauer B, Tunn P. Thermal Ablation in Bone Tumors. In: Minimally Invasive Tumor Therapies. Vol 167. ; 2006:135-146.

  37. Knavel E, Brace C. Tumor Ablation: Common Modalities and Generak Practices. Tech Vasc Interv Radiol.2013;16(4):192-200.

  38. Nazario J, Hernandez J, Tam AL. Thermal Ablation of Painful Bone Metastases. Tech Vasc Interv Radiol. 2011;14(3):150-159.

  39. Albisinni U, Bazzocchi A, Bettelli G, et al. Treatment of osteoid osteoma of the elbow by radiofrequency thermal ablation. J Shoulder Elb Surg. 2014;23(1):e1-e7.

  40. Lanza E, Thouvenin Y, Viala P, et al. Osteoid Osteoma Treated by Percutaneous Thermal Ablation: When Do We Fail? A Systematic Review and Guidelines for Future Reporting. Cardiovasc Intervent Radiol. 2013:1-10.

  41. Pimolsanti R, Wongkajornsilpa A, Chotiyarnwong P, Asavamongkolku A. Effects of thermoablation with or without caffeine on giant cell tumour of bone. 2015;23(1):95-99.

  42. Ruiz Santiago F, Del Mar Castellano García M, Guzmán Álvarez L, Martínez Montes JL, Ruiz García M, Tristán Fernández JM. Percutaneous treatment of bone tumors by radiofrequency thermal ablation. Eur J Radiol. 2011;77(1):156-163.

  43. Nicholas Kurup A, Callstrom MR. Ablation of musculoskeletal metastases: Pain palliation, fracture risk reduction, and oligometastatic disease. Tech Vasc Interv Radiol. 2013;16(4):253-261.

  44. Dupuy DE, Goldberg SN. Image-guided Radiofrequency Tumor Ablation : Challenges and Opportunities — Part II. J Vasc Interv Radiol. 2001; 12(10):1135-1148.

  45. Liu Z, Ahmed M, Sabir A, Humphries S, Goldberg SN. Computer modeling of the effect of perfusion on heating patterns in radiofrequency tumor ablation. Int J Hyperthermia. 2007;23(February):49-58.

  46. Filippiadis DK, Tutton S, Kelekis A. Percutaneous bone lesion ablation. Radiol Medica. 2014; 119(7):462-469.

  47. Deschamps F, Farouil G, Ternes N, et al. Thermal ablation techniques: A curative treatment of bone metastases in selected patients? Eur Radiol. 2014;24(8):1971-1980. -1.

  48. Santiago FR, Del Mar Castellano García M, Montes JLM, García MR, Fernández JMT. Treatment of bone tumours by radiofrequency thermal ablation. Curr Rev Musculoskelet Med. 2009;2(1):43-50.

  49. Hoffmann RT, Jakobs TF, Kubisch CH, et al. Radiofrequency ablation in the treatment of osteoid osteoma-5-year experience. Eur J Radiol. 2010;73(2):374-379.

  50. Carrafiello G, Laganà D, Mangini M, et al. Microwave tumors ablation: Principles, clinical applications and review of preliminary experiences. Int J Surg. 2008;6(SUPPL. 1):65-69..

  51. Scott SJ, Salgaonkar V, Prakash P, Burdette EC, Diederich CJ. Interstitial ultrasound ablation of vertebral and paraspinal tumours: Parametric and patient-specific simulations. Int J Hyperth. 2014; 30(4):228-244.

  52. Brace CL. Radiofrequency and Microwave Ablation of the Liver, Lung, Kidney, and Bone: What Are the Differences? Curr Probl Diagn Radiol. 2009 ;38(3):135-143.

  53. Fan Q-Y, Ma B-A, Zhou Y, Zhang M-H, Hao X-B. Bone Tumors of the Extremities or Pelvis Treated by Microwave-Induced Hyperthermia. Clin Orthop Relat Res. 203AD;406(1):165-175.

  54. Pusceddu C, Sotgia B, Fele RM, Melis L. Treatment of Bone Metastases with Microwave Thermal Ablation. J Vasc Interv Radiol. 24(2):229-233.

  55. Metastasis B, Napoli A, Anzidei M, et al. MR Imaging – guided Focused Ultrasound for Treatment of. 2013:1555-1569.

  56. Al-Bataineh O, Jenne J, Huber P. Clinical and future applications of high intensity focused ultrasound in cancer. Cancer Treat Rev. 2012;38(5):346-353.

  57. Chen W, Zhu H, Zhang L, et al. Primary bone malignancy: effective treatment with high-intensity focused ultrasound ablation. Radiology. 2010;255(3):967-978.

  58. Maloney E, Hwang JH. Emerging HIFU applications in cancer therapy. Int J Hyperth. 2014;(August):1-8.

  59. Gutiérrez-Martínez J, Rico-Martínez G. Sistema de hipertermia hidrica controlada con mapeo para oncología ósea. Rev Mex Ing Biomédica. 2008; XXIX(1):7-14.

  60. Gastélum R, Rico M, Vega I, et al. Efecto biológico de la hipertermia hídrica controlada sobre hueso sano de conejos. Acta Ortopédica Mex. 2014;28(5):297-304.

  61. Franckena M. Hyperthermia for the Treatment of Locally Advanced Cervix Cancer.; 2010. http://repub.eur.nl/res/pub/20549/.

  62. Okhai T a, Smith CJ. Principles and Application of RF System for Hyperthermia Therapy. In: Hyperthermia. ; 2013:171-184.

  63. National Institute of Integrative Medicine. Regional Hyperthermia Clinical Trial. http://www.niim.com. au/clinic/services/hyperthermia/hyperthermia-faq#q8. Published 2015.

  64. Asociación Mexicana de Lucha Contra el Cáncer . Osteosarcoma: el cáncer de hueso más común de la edad pediátrica. Rayuela Rev Iberoaméricama Sobre Niñez y Juv en Lucha por sus Derechos.:215-222.

  65. Martinez Tello F, Manjón Luengo P, Montes Moreno S. Variantes de condrosarcoma. Rev española Patol. 2006;39(2):69-79.

  66. Melo IG, Martínez VC. Tumores Oseos Condroides: Condromas Versus Condrosarcomas Conven- cionales. Rev Chil Radiol. 2005;11(1):170-178.

  67. Bernstein M, Kovar H, Paulussen M, Randall RL, Schuck A, Teot LA. Ewing ’ s Sarcoma Family of Tumors : Current Management. Oncologist. 2006;11(C):503-519.

  68. Parikh M, Samujh R, Kanojia RP. Peripheral Primitive Neuroectodermal Tumor of the Chest Wall in Childhood : Clinico-Pathological Significance , Management and Literature Review. Chang Gung Med J. 2011;34(2):213-217.

  69. Salvador J, Olalde U, Guillermo H, et al. Sarcoma de Ewing extraóseo. Bol Med Hosp Infant Mex. 2013;70(6):477-481.

  70. Fletcher CDM, Unni KK. World Health Organization Classification of Tumours Pathology and Genetics of Tumours of Soft Tissue and Bone.; 2002.

  71. Romeo S, Bovée JVMG, Kroon HM, et al. Malignant fibrous histiocytoma and fibrosarcoma of bone: A re-assessment in the light of currently employed morphological, immunohistochemical and molecular approaches. Eur J Pathol. 2012;461(5):561-570.

  72. Rosa-pérez LJH. Tumores malignos de los huesos. In: Cirugía: II Cirugía Ortopédica Y Traumatología. Universidad Nacional Mayor de San Marcos (Lima). Facultad de Medicina. Escuela Académico Profesional de Medicina Humana. Departamento Académico de Cirugía; 2000:305-318.

  73. Mercado MV, Samith MA, Ghiringhelli MA, et al. Fibrosarcoma: Caso clínico. Rev Otorrinolaringol,. 2005:241-249.

  74. Chakarun CJ, Forrester DM, Gottsegen CJ, Patel DB, White E a, Matcuk GR. Giant cell tumor of bone: review, mimics, and new developments in treatment. Radiographics. 2013;33(1):197-211.

  75. Óleas Poveda J, Alvarado Chávez T, Abad Ramirez C. Tumor de células gigantes malignizado. Presentación de un caso. MedPre, Rev Interuniv e Interhospitalaria del Ecuador. 2011;1(1):49-53.

  76. Marxen J, Uribe T. Tumor de células gigantes de hueso: trasformación maligna secundaria sin radioterapia. Rev Médico Cient. 2001;14(2):28-35.

  77. Bryson DJ, Wicks L, Ashford RU. The investigation and management of suspected malignant pathological fractures: A review for the general orthopaedic surgeon. Injury. 2015:1-9.

  78. American Cancer Society. Metástasis En Los Hue- sos. ; 2014.

  79. Therapy R, Cdks B. The Science Behind Radiation Therapy. Am Cancer Soc. 2014:15.

  80. Icrp. Annals of the ICRP 60.; 1990.

  81. Wodaje T. Long Term Effects of Radiation-Induced Osteonecrosis of the Pelvis Caused Complete Failure of Total Hip Arthroplasty. Surg Sci. 2012;3(7):373-375.

  82. Mitsimponas KT, Moebius P, Amann K, et al. Osteo-radio-necrosis (ORN) and bisphosphonate-related osteonecrosis of the jaws (BRONJ): The histopathological differences under the clinical similarities. Int J Clin Exp Pathol. 2014;7(2):496-508.

  83. Oh D, Huh SJ. Insufficiency fracture after radiation therapy. Radiat Oncol J. 2014;32(4):213-220.

  84. Nicholls F, Janic K, Filomeno P, Willett T, Grynpas M, Ferguson P. Effects of radiation and surgery on healing of femoral fractures in a rat model. J Orthop Res. 2013;31(8):1323-1331.

  85. Bluemke D a, Fishman EK, Scott WW. Skeletal complications of radiation therapy. Radiographics. 1994;14(1):111-121.

  86. Agency for Healthcare Research and Quality. Statistical Brief #125. Healthcare Cost and Utilization Project (HCUP). www.hcup-us.ahrq.gov/reports /statbriefs/sb125.jsp. Published 2012.

  87. Ramirez-Agudelo V. Estudio de Factibilidad Para La Unidad de Radioterapia Del Centro Oncológico de Antioquia S.A.; 2014.

  88. Hess G, Barlev A, Chung K, Hill JW, Fonseca E. Cost of palliative radiation to the bone for patients with bone metastases secondary to breast or prostate cancer. Radiat Oncol. 2012;7(1):168.

  89. Nickman NA, Ye X, Gaffney DK, et al. radiotherapy ( EBRT ) use for bone. J Community Support Oncol. 2014;13(3):95-103.

  90. Health A. Total Cost of Cancer Care by Site of Service : Physician Office vs Outpatient Hospital. 2012;(March).




2020     |     www.medigraphic.com