2019, Número 3
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Alerg Asma Inmunol Pediatr 2019; 28 (3)
La estabilización del mastocito por la vitamina D
Espinosa ZJR, Huerta LJG, Ortega-Martell JA
Idioma: Español
Referencias bibliográficas: 30
Paginas: 96-101
Archivo PDF: 210.61 Kb.
RESUMEN
Los estudios del mastocito y la vitamina D tienen una historia en su investigación y conocimiento que a veces se juntan mucho, como ocurrió en 1931, cuando Adolf Windaus logró la cristalización de la vitamina D y también descubrió la histamina. Por mucho tiempo, la vitamina D se reconoció como la vitamina antirraquítica. Fue en los años 1960 que se esclareció el metabolismo de la vitamina D. A partir de los últimos años, con el desarrollo de la inmunología, alergia y biología molecular, y ligados a los estudios del metabolismo de la vitamina D y la función del mastocito, gradualmente se conocen las múltiples funciones de la vitamina D en el organismo, especialmente en el mastocito, produciendo un desarrollo importante en el conocimiento de la inmunología y alergia. La estabilización del mastocito por la vitamina D es un conocimiento que nos otorgan los múltiples estudios recientes.
REFERENCIAS (EN ESTE ARTÍCULO)
Wernersson S, Pejler G. Mast cell secretory granules: armed for battle. Nat Rev Immunol. 2014; 14 (7): 478-494.
Lieberman P, Garvey LH. Mast cells and anaphylaxis. Curr Allergy Asthma Rep. 2016; 16 (3): 20.
Finkelman FD, Khodoun MV, Strait R. Human IgE-independent systemic anaphylaxis. J Allergy Clin Immunol. 2016; 137 (6): 1674-1680.
Afrin LB. Mast cell activation disease and the modern epidemic of chronic inflammatory disease. Transl Res. 2016; 174: 33-59.
Veatch SL, Chiang EN, Sengupta P, Holowka DA, Baird BA. Quantitative nanoscale analysis of IgE-FcεRI clustering and coupling to early signaling proteins. J Phys Chem B. 2012; 116 (23): 6923-6935.
Lin S, Cicala C, Scharenberg AM, Kinet JP. The Fc(epsilon)RIbeta subunit functions as an amplifier of Fc(epsilon)RIgamma-mediated cell activation signals. Cell. 1996; 85 (7): 985-995.
Sibilano R, Frossi B, Pucillo CE. Mast cell activation: a complex interplay of positive and negative signaling pathways. Eur J Immunol. 2014; 44 (9): 2558-2566.
Giulietti A, van Etten E, Overbergh L, Stoffels K, Bouillon R, Mathieu C. Monocytes from type 2 diabetic patients have a pro-inflammatory profile. 1,25-Dihydroxyvitamin D(3) works as anti-inflammatory. Diabetes Res Clin Pract. 2007; 77 (1): 47-57.
Calton EK, Keane KN, Newsholme P, Soares MJ. The impact of vitamin D levels on inflammatory status: a systematic review of immune cell studies. PLoS One. 2015; 10 (11): e0141770.
Sarkar S, Hewison M, Studzinski GP, Li YC, Kalia V. Role of vitamin D in cytotoxic T lymphocyte immunity to pathogens and cancer. Crit Rev Clin Lab Sci. 2016; 53 (2): 132-145.
Wei R, Christakos S. Mechanisms underlying the regulation of innate and adaptive immunity by vitamin D. Nutrients. 2015; 7 (10): 8251-8260.
Neve A, Corrado A, Cantatore FP. Immunomodulatory effects of vitamin D in peripheral blood monocyte-derived macrophages from patients with rheumatoid arthritis. Clin Exp Med. 2014; 14 (3): 275-283.
Yip KH, Kolesnikoff N, Yu C, Hauschild N, Taing H, Biggs L et al. Mechanisms of vitamin D₃ metabolite repression of IgE-dependent mast cell activation. J Allergy Clin Immunol. 2014; 133 (5): 1356-1364, 1364.e1-14.
Feng BS, Zheng PY, Chen X, Liao XQ, Yang PC. Investigation of the role of cholera toxin in assisting the initiation of the antigen-specific Th2 response. Immunol Invest. 2008; 37 (8): 782-797.
Jung HS, Kim MH, Gwak NG, Im YS, Lee KY, Sohn Y et al. Antiallergic effects of Scutellaria baicalensis on inflammation in vivo and in vitro. J Ethnopharmacol. 2012; 141 (1): 345-349.
Consiglio M, Destefanis M, Morena D, Foglizzo V, Forneris M, Pescarmona G et al. The vitamin D receptor inhibits the respiratory chain, contributing to the metabolic switch that is essential for cancer cell proliferation. PLoS One. 2014; 9 (12): e115816.
Ban T, Sato GR, Nishiyama A, Akiyama A, Takasuna M, Umehara M et al. Lyn kinase suppresses the transcriptional activity of IRF5 in the TLR-MyD88 pathway to restrain the development of autoimmunity. Immunity. 2016; 45 (2): 319-332.
van Heel DA, Udalova IA, De Silva AP, McGovern DP, Kinouchi Y, Hull J et al. Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors. Hum Mol Genet. 2002; 11 (11): 1281-1289.
Finn DF, Walsh JJ. Twenty-first century mast cell stabilizers. Br J Pharmacol. 2013; 170 (1): 23-37.
Jeong YI, Kim YJ, Ju JW, Hong SH, Lee MR, Cho SH et al. Identification of anti-allergic effect of Clonorchis sinensis-derived protein venom allergen-like proteins (CsVAL). Biochem Biophys Res Commun. 2014; 445 (3): 549-555.
Amir-Moazami O, Alexia C, Charles N, Launay P, Monteiro RC, Benhamou M. Phospholipid scramblase 1 modulates a selected set of IgE receptor-mediated mast cell responses through LAT-dependent pathway. J Biol Chem. 2008; 283 (37): 25514-25523.
Meckel K, Li YC, Lim J, Kocherginsky M, Weber C, Almoghrabi A et al. Serum 25-hydroxyvitamin D concentration is inversely associated with mucosal inflammation in patients with ulcerative colitis. Am J Clin Nutr. 2016; 104 (1): 113-120.
Silwal P, Shin K, Choi S, Kang SW, Park JB, Lee HJ et al. Adenine suppresses IgE-mediated mast cell activation. Mol Immunol. 2015; 65 (2): 242-249.
Silvagno F, Consiglio M, Foglizzo V, Destefanis M, Pescarmona G. Mitochondrial translocation of vitamin D receptor is mediated by the permeability transition pore in human keratinocyte cell line. PLoS One. 2013; 8 (1): e54716.
Sequeira VB, Rybchyn MS, Tongkao-On W, Gordon-Thomson C, Malloy PJ, Nemere I et al. The role of the vitamin D receptor and ERp57 in photoprotection by 1α,25-dihydroxyvitamin D3. Mol Endocrinol. 2012; 26 (4): 574-582.
Rawlings DJ, Schwartz MA, Jackson SW, Meyer-Bahlburg A. Integration of B cell responses through Toll-like receptors and antigen receptors. Nat Rev Immunol. 2012; 12 (4): 282-294.
Maruotti N, Cantatore FP. Vitamin D and the immune system. J Rheumatol. 2010; 37 (3): 491-495.
Zhang Y, Leung DY, Richers BN, Liu Y, Remigio LK, Riches DW et al. Vitamin D inhibits monocyte/macrophage proinflammatory cytokine production by targeting MAPK phosphatase-1. J Immunol. 2012; 188 (5): 2127-2135.
Calton EK, Keane KN, Soares MJ. The potential regulatory role of vitamin D in the bioenergetics of inflammation. Curr Opin Clin Nutr Metab Care. 2015; 18 (4): 367-373.
Daly RM, Gagnon C, Lu ZX, Magliano DJ, Dunstan DW, Sikaris KA et al. Prevalence of vitamin D deficiency and its determinants in Australian adults aged 25 years and older: a national, population-based study. Clin Endocrinol (Oxf). 2012; 77 (1): 26-35.