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Revista de Divulgación del INSTITUTO DE MEDICINA FORENSE de la UNIVERSIDAD VERACRUZANA

2016, Número 1

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Rev Mex Med Forense 2016; 1 (1)


Determinación toxicológica de cocaína en humor vítreo

García H, Melo-Santiesteban G, Hermida-Moreno A

Idioma: Español
Referencias bibliográficas: 30
Paginas: 36-44
Archivo PDF: 358.97 Kb.


RESUMEN

La determinación toxicológica postmortem de cocaína y sus derivados tradicionalmente ha sido realizada en muestras de sangre y orina; sin embargo, en algunos casos no se cuenta con este tipo de sustratos, lo cual obliga al uso de sustratos alternativos; de ellos, en años recientes ha surgido interés en el uso del humor vítreo para determinación de cocaína y benzoilecgonina como su principal metabolito. En la presente revisión analizamos las características que hacen al humor vítreo un sustrato útil para el análisis toxicológico de cocaína y derivados, la metodología usada en la actualidad así como los resultados obtenidos en estudios recientes acerca de la sensibilidad y especificidad de su determinación.


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