medigraphic.com

2006, Número 2

<< Anterior Siguiente >>

Bioquimia 2006; 31 (2)


Variación del HLA-B en poblaciones mexicanas

Acuña-Alonzo V, Silva-Ramírez B, Castillo-Vázquez M, Granados-Arriola J

Idioma: Español
Referencias bibliográficas: 41
Paginas: 49-58
Archivo PDF: 127.64 Kb.


RESUMEN

En este trabajo analizamos por primera vez las distancias genéticas entre grupos indígenas y mestizos mexicanos con el gen HLA-B, el más polimórfico del Complejo Principal de Histocompatibilidad (MHC). Se obtuvieron las frecuencias alélicas de 10 poblaciones indígenas reportadas en la literatura para el gen HLA-B. Además, se incluyeron las frecuencias de mestizos mexicanos (n = 102), asiáticos del noreste (n = 380), euroamericanos (n = 287) y afroamericanos (n = 396) de EUA, kurdos (n = 101), coreanos (n = 29) mandenka de Senegal (n = 68) y malayos del sur de Asia (n = 94) cuyos datos fueron obtenidos de la base de datos MHC Anthropology. La variación del sistema HLA en el componente amerindio muestra un patrón singular, que se caracteriza por un polimorfismo restringido y un número considerable de nuevos alelos de alta resolución dentro de ciertos linajes alélicos. Estas peculiaridades se intentan vincular a los factores más sobresalientes de la historia biológica de las poblaciones indígenas. En cuanto a los mestizos, la variación se caracteriza por la distribución de las frecuencias en un número mayor de alelos, lo cual es congruente con la diversidad de las aportaciones genéticas ancestrales a los mestizos mexicanos.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. McCluskey J, Pech CA. The human leucocyte antigens and clinical medicine: an overview. Rev Immunogenetics 1999; 1: 3-20.

  2. Charron D. Immunogenetics today: HLA, MHC and much more. Curr Opin Immunol 2005; 17: 493-497.

  3. Riley E, Olerup O. HLA polymorphism and evolution. Immunol Today 1992; 13: 333-335.

  4. Yeager M, Hughes AI, Austin L. Evolution of the mammalians MHC: nature selection, recombination and convergent evolution. Immunol Rev 1999; 167: 45-58.

  5. Clayton J, Lonjou C. Allele and haplotype frequencies for HLA loci in various ethnic groups. In: D. Charron, ed. Genetics Diversity of HLA, Functional and medical implications. Paris: EDK, 1996: 650-820.

  6. Anthony Nolan Research Institute. Full List of HLA Class I alleles assigned as of July 2004. Disponible en: http://www.anthonynolan.com/HIG/lists/class1list.html.

  7. Anthony Nolan Research Institute. Full List of HLA Class II alleles assigned as of July 2004. Disponible en: http://www.anthonynolan.com/HIG/lists/class2list.html.

  8. Williams F, Meenagh A, Darke C, Acosta A, Daar AS, Gorodezky C, et al. Analysis of the distribution of HLA –B alleles in population from five continents. Human Immunol 2001; 62: 645-650.

  9. Loeza F, Vargas-Alarcón G, Granados J. Distribution of class I and class III MHC antigens in the Tarasco Amerindians. Human Immunol 2002; 63: 143-148.

  10. Hollenbach JA, Thomson G, Klitz W. HLA diversity, differentiation, and haplotype evolution in Mesoamerican Natives. Human Immunol 2001; 62: 378-390.

  11. Vargas-Alarcón G, Hernández-Pacheco G, Arnaiz-Villena. Distribution of HLA-B alleles in Mexican Amerindian populations. Immunogenetics 2003; 54: 756-760.

  12. Gómez-Casado E, Martínez-Laso J, Arnaiz-Villena A. Origin of Mayans according to HLA genes and the uniqueness of Amerindians. Tissue Antigens 2002; 61: 425-436.

  13. MHC-Anthropology. Disponible en: http://www.ncbi.nlm.nih. gov/mhc.

  14. Nei M. Genetics distances between populations. Am Nat 1972; 106: 283.

  15. PHYLIP (Phylogeny Inference Package) version 3.6. Distributed by Felsenstein, J. Department of Genome Sciences, University of Washington, Seattle. 2004.

  16. TreeView version 1.6.5. Distributed by Roderic DM. Disponible en: http://taxonomy.zoology.gla.ac.uk/rod/rod.html. 2001.

  17. Sandoval E. Grupos etnolingüísticos en el México del siglo XXI. Papeles de Población. 2002; 34: 219-235.

  18. Ruhlen MA. A guide to the word’s languages I. Classification. London: Edward Arnold. 1987.

  19. Cavalli-Sforza L, Menozzi P, Piazza A. The history and geography of human genes. New Jersey, USA: Princeton University Press. 1994.

  20. Lisker R, Ramírez E, Pérez RB, Granados J, Babinsky V. Gene frequencies and admixture estimates in four Mexican urban centers. Hum Biol 1990; 62: 791-801.

  21. Zavala C, Alatorre S, Lisker R. Distancias génicas entre algunos grupos indígenas mexicanos. Est Antropol Biol 1982; 1: 141-154.

  22. Salzano FM. Molecular variability in Amerindians: widespread but uneven information. Anais da Acad Brasileira de Ciencias 2002; 74: 223-263.

  23. Salzano FM, Bortolini MC. The evolution and genetics of Latin American populations. UK: Cambridge University Press. 2002.

  24. Mulligan CJ, Hunley K, Long J. Population genetics, history, and health patterns in Native Americans. Ann Rev Genomics Hum Genet 2004; 5: 295-315.

  25. Bonatto SL, Salzano FM. A single and early migration for the peopling of the Americas supported by mitochondrial DNA sequence data. PNAS 1997; 94: 1866-1871.

  26. Pucciarelli HM, Sardi ML, Jiménez JC, Serrano-Sánchez C. Early peopling and evolutionary diversification in America. Quatern Intern 2003; 109: 123-132.

  27. Erlich HA, Mack SJ, Bergstrom T, Gyllensten UB. HLA class II alleles in Amerindian populations: implications for the evolution of HLA polymorphism and the colonization of the Americas. Hereditas 1997; 127: 19-24.

  28. Arnaiz-Villena A, Vargas-Alarcón G, Granados J. HLA genes in Mexican Mazatecans, the peopling of the Americas and the uniqueness of Amerindians. Tissue Antigens 2000; 56: 405-416.

  29. Tsuneto LT, Probst CM, Petzl-Erler ML. HLA class II diversity in seven Amerindian populations. Clues about the origins of the Ache. Tissue Antigens 2003; 62: 512-526.

  30. Greenberg JH, Turner C, Zegura SL. The settlement of the Americans: a comparison of the linguistic, dental, and genetic evidence. Curr Anthropol 1986; 27: 477-97.

  31. Greenberg JH. Language in the Americas. California, USA: Stanford University Press. 1987.

  32. Murray GC, Montiel MM, Persellin RH. Distribution of HLA antigens in a Mexican-American population and a comparison with two similar populations from different geographical locals. Tissue Antigens 1978; 12: 337-340.

  33. Gorodezky C, Teran L, Escobar-Gutiérrez A. HLA frequencies in a Mexican Mestizo population. Tissue Antigens 1979; 14: 347-352.

  34. Arellano J, Vallejo M, Estrada HG, Kretschmer RR. HLA profile of the Mexican Mestizo population. Tissue Antigens 1981; 18: 242-246.

  35. Chauvenet PH, Anderson SA, Banowsky LH. HLA frequencies in a Mexican American population. Tissue Antigens 1981; 17: 323-31.

  36. Olivo-Díaz A, Gómez-Casado E, Arnaiz-Villena A. A new HLA-B15 allele (B*1541) found in a Mexican of Nahua (Aztec) descent. Immunogenetics 1998; 48: 148-151.

  37. Vargas-Alarcón G, Martínez-Laso J, Arnaiz-Villena A. Description of a novel HLA-B35 (B*3514) allele found in a Mexican family of Nahua Aztec descent. Human Immunol 1996; 45: 148-151.

  38. Vargas-Alarcón G, Alvarez M, Arnaiz-Villena A. A new HLA-B35 (B*3516) allele found in a Mexican of Nahua (Aztec) descent. Immunogenetics 1996; 43: 244-245.

  39. Vargas-Alarcón G, Martínez-Laso J, Arnaiz-Villena A. A novel HLA-B35 (B*3517) allele found in a Mexican of Otomi descent. Tissue Antigens 1996; 47: 547-550.

  40. Vargas-Alarcón G, Gómez-Casado E, Arnaiz-Villena A. Differences in intron 2 sequences between B*39061 y B*39062 in Amerindians: comparison with those of B*3901, B*5101, and B*52012 alleles. Immunogenetics 1997; 45: 436-439.

  41. Vargas-Alarcón G, Gómez-Casado E, Arnaiz-Villena A. Description of a new HLA-B40 allele (B*4011) found in a Mexican individual of Nahua (Aztec) descent. Immunogenetics 1997; 46: 359-360.




2020     |     www.medigraphic.com