2018, Número 6
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Acta Pediatr Mex 2018; 39 (6)
Metahemoglobinemia por fenazopiridina: reporte de un caso con enfoque diagnóstico
Pérez-Tuñón JG, Martiñón-Ríos R, Figueroa-Rivera M
Idioma: Español
Referencias bibliográficas: 30
Paginas: 355-360
Archivo PDF: 321.40 Kb.
RESUMEN
Introducción: La metahemoglobinemia adquirida es un trastorno en el que la hemoglobina
es oxidada por un agente externo, impidiendo el transporte y entrega del
oxígeno a los tejidos. Uno de los agentes oxidantes es el clorhidrato de fenazopiridina,
una anilina con efecto analgésico empleada para tratar el dolor de la vía urinaria baja.
Caso clínico: Paciente de 12 años, que ingirió 250 mg de amitriptilina, 1.8 g de
fenazopiridina y 14.5 mg de clonazepam en un intento suicida, desarrollando metahemoglobinemia
que requirió el empleo de azul de metileno en dos ocasiones.
Introducciones: La metahemoglobinemia es subdiagnosticada a pesar de poder originar
complicaciones graves e, incluso, la muerte. Se diagnostica mediante cooximetría.
Cuando ésta no está disponible, además de los datos clínicos, debe evaluarse la brecha
de saturación y la sangre color “chocolate”.
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