2019, Número 1
<< Anterior Siguiente >>
Rev Mex Anest 2019; 42 (1)
Beneficio anestésico y analgésico de la ketamina como adyuvante a anestesia general en pediátricos sometidos a cateterismo cardíaco
Mari-Zapata D, Ángeles-de la Torre R, Molina-Méndez F
Idioma: Español
Referencias bibliográficas: 40
Paginas: 28-34
Archivo PDF: 218.87 Kb.
RESUMEN
Objetivo: Conocer si la ketamina a dosis subanestésicas disminuye el dolor agudo, agitación y requerimientos analgésicos en cateterismo cardíaco.
Material y métodos: Pacientes de dos meses a siete años, anestesia general, ASA II-IV. Dos grupos: K: ketamina y F: fentanyl más analgésico; sevoflurano 1-1.2 CAM y ventilación mecánica. Registro de signos vitales: basales, inicio del procedimiento y emersión. Valoración con FLACC y Ramsay a la emersión y al llegar a su cama, se administró analgésico con FLACC › 4.
Resultados: 121 pacientes, grupo K: 52.8%, grupo F: 47%, edad: 47 ± 26.38 meses, tiempo anestésico: 100.22 ± 38.7 min. Variables cardiovasculares sin diferencia intergrupos en relación al tiempo. Requerimientos analgésicos a las seis horas en grupo K y F hasta las 10 horas. FLACC en emersión leve 86.8%; 49% grupo K y 37% grupo F: (p = 0.02), al llegar a piso FLACC leve 92%, grupo K 52% y 40.4% grupo F (p = 0.002). A las seis horas FLACC › 4 en grupo K (p = 0.002). Grado de sedación a la extubación menor en el grupo K (p = 0.03).
Conclusiones: La ketamina preserva estabilidad hemodinámica, disminuye agitación y dolor las primeras seis horas postprocedimiento; se puede utilizar como coadyuvante anestésico seguro.
REFERENCIAS (EN ESTE ARTÍCULO)
Andropoulos DB, Stayer SA. An anesthesiologist for all pediatric cardiac catheterizations: luxury or necessity? J Cardiothorac Vasc Anesth. 2003;17:683-685.
Oklü E, Bulutcu FS, Yalçin Y, Ozbek U, Cakali E, Bayindir O. Which anesthetic agent alters the hemodynamic status during pediatric catheterization? Comparison of propofol versus ketamine. J Cardiothorac Vasc Anesth. 2003;17:686-690.
Schmid RL, Sandler AN, Katz J. Use and efficacy of low-dose ketamine in the management of acute postoperative pain: a review of current techniques and outcomes. Pain. 1999;82:111-125.
Xu J, Lei H. Ketamine-an update on its clinical uses and abuses. CNS Neurosci Ther. 2014;20:1015-1020.
Jobeir A, Galal MO, Bulbul ZR, Solymar L, Darwish A, Schmaltz AA. Use of low-dose ketamine and/or midazolam for pediatric cardiac catheterization: is an anesthesiologist needed. Pediatr Cardiol. 2003;24:236-243.
Morgan CJA, Curran HV. Ketamine use: a review. Addiction. 2011;107:27-38.
Roelofse JA. The evolution of ketamine applications in children. Pediatr Anesth. 2010;20:240-245.
Bell RF, Dahl JB, Moore RA, Kalso E. Perioperative ketamine for acute postoperative pain. Cochrane Database Syst Rev. 2006;CD004603.
Zukowski M, Kotfis K. The use of opioid adjuvants in perioperative multimodal analgesia. Anaesthesiol Intensive Ther. 2012;44:42-46.
Elia N, Tramer MR. Ketamine and postoperative pain-a quantitative systematic review of randomized trials. Pain. 2005;113:61-70.
Cavallieri S, Canepal P. Dolor agudo post-quirúrgico en pediatría evaluación y tratamiento. Rev Med Clin Condes. 2007;18:207-216.
Merkel SI, Voepel-Lewis T, Shayevitz JR, Malviya S. The FLACC: a behavioral scale for scoring postoperative pain in young children. Pediatr Nurs. 1997;23:293-297.
Bai J, Hsu L, Tang Y, van Dijk M. Validation of the COMFORT Behavior scale and the FLACC scale for pain assessment in Chinese children after cardiac surgery. Pain Manag Nurs. 2012;13:18-26.
Chen MF. Pain assessment for infants and children: FLACC scale. Foreign Medical Sciences: Nursing Foreign Medical Science. 2003;22:289-290.
Voepel-Lewis T, Merkel S, Tait AR, Trzcinka A, Malviya S. The reliability and validity of the Face, Legs, Activity, Cry, Consolability observational tool as a measure of pain in children with cognitive impairment. Anesth Analg. 2002;95:1224-1229.
Willis MH, Merkel SI, Voepel-Lewis T, Malviya S. FLACC behavioral pain assessment scale: a comparison with the child’s self-report. Pediatr Nurs. 2003;29:195-198.
Faithfull NS, Haider R. Ketamine for cardiac catheterization. Anaesthesia. 1971;26:318-323.
Khutia SK, Mandal MC, Das S, Basu SR. Intravenous infusion of ketamine-propofol can be an alternative to intravenous infusion of fentanyl-propofol for deep sedation and analgesia in paediatric patients undergoing emergency short surgical procedures. Indian J Anaesth. 2012;56:145-150.
Hamid A. Anesthesia for cardiac catheterization procedures. Heart Lung Vessel. 2014;6:225-231.
Bennett D, Marcus R, Stokes M. Incidents and complications during pediatric cardiac catheterization. Paediatr Anaesth. 2005;15:1083-1088.
Shook D, Gross W. Offsite anesthesiology in the cardiac catheterization lab. Curr Opin Anaesthesiol. 2007;20:352-358.
Abbas SM, Rashid A, Latif H. Sedation for children undergoing cardiac catheterization: a review of literature. J Pak Med Assoc. 2012;62:159-163.
Lebovic S, Reich DL, Steinberg LG, Vela FP, Silvay G. Comparison of propofol versus ketamine for anesthesia in pediatric patients undergoing cardiac catheterization. Anesth Analg. 1992;74:490-494.
Baysal A, Polat TB, Yalcin Y, Celebi A. The use of basic parameters for monitoring the haemodynamic effects of midazolam and ketamine as opposed to propofol during cardiac catheterization. Cardiol Young. 2014;24:351-358.
Hasija S, Chauhan S, Makhija N. Comparison of the hemodynamic effects of the induction agents ketamine, etomidate and sevoflurane using the model of electrical velocimetry based cardiac output monitoring in pediatric cardiac surgical patients. World J Cardiovasc Surg. 2014;4:167-175.
Morray JP, Lynn AM, Stamm SJ, Herndon PS, Kawabori I, Stevenson JG. Hemodynamic effects of ketamine in children with congenital heart disease. Anesth Analg. 1984;63:895-899.
Gooding JM, Dimick AR, Tavakoli M, Corssen G. A physiologic analysis of cardiopulmonary responses to ketamine anesthesia in noncardiac patients. Anesth Analg. 1977;56:813-816.
Sungur Ulke Z, Kartal U, Orhan Sungur M, Camci E, Tugrul M. Comparison of sevoflurane and ketamine for anesthetic induction in children with congenital heart disease. Paediatr Anaesth. 2008;18:715-721.
Williams GD, Philip BM, Chu LF. Ketamine does not increase pulmonary vascular resistance in children with pulmonary anesthesia and spontaneous ventilation. Anesth Analg. 2007;105:1578-1584.
Williams GD, Maan H, Ramamoorthy C, Kamra K, Bratton SL, Bair E, et al. Perioperative complications in children with pulmonary hypertension undergoing general anesthesia with ketamine. Paediatr Anaesth. 2010;20:28-37.
Meretoja OA, Rautiainen P. Alfentanil and fentanyl sedation in infants and small children during cardiac catheterization. Can J Anaesth. 1990;37:624-628.
Lam JE, Lin EP, Alexy R, Aronson LA. Anesthesia and the pediatric cardiac catheterization suite: a review. Paediatr Anaesth. 2015;25:127-134.
Doyle L, Coletti JE. Pediatric procedural sedation and analgesia. Pediatr Clin North Am. 2006;53:279-292.
Reich DL, Silvay G. Ketamine: an update on the first 25 years of clinical experience. Can J Anaesth. 1989;36:186-197.
Jouguelet-Lacoste J, La Colla L, Schilling D, Chelly JE. The use of intravenous infusion or single dose of low-dose ketamine for postoperative analgesia: a review of the current literature. Pain Med. 2015;16:383-403.
Anis NA, Berry SC, Burton NR, Lodge D. The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspartate. Br J Pharmacol. 1983;79:565-575.
Subramaniam K, Subramaniam B, Steinbrook RA. Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review. Anesth Analg. 2004;99:482-495.
Shamim F, Ullah H, Khan FA. Postoperative pain assessment using four behavioral scales in Pakistani children undergoing elective surgery. Saudi J Anaesth. 2015;9:174-178.
Kararmaz A, Kaya S, Karaman H, Turhanoglu S, Ozyilmaz MA. Intraoperative intravenous ketamine in combination with epidural analgesia: postoperative analgesia after renal surgery. Anesth Analg. 2003;97:1092-1096.
Karapinar B, Yilmaz D, Demirağ K, Kantar M. Sedation with intravenous ketamine and midazolam for painful procedures in children. Pediatr Int. 2006;48:146-151.