2019, Número 01
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Revista Médica Sinergia 2019; 4 (01)
Microbiota y disbiosis vaginal
Mora ASÁ
Idioma: Español
Referencias bibliográficas: 35
Paginas: 3-13
Archivo PDF: 270.42 Kb.
RESUMEN
El cuerpo humano está colonizado por una gran cantidad de microbios,
los cuales de manera colectiva se les llama microbiota humana. La
relación entre ellos y la salud humana ha sido de gran estudio en los
últimos años.
A nivel vaginal, la presencia de estos microorganismos se ha
correlacionado con el mantenimiento de un ecosistema vaginal
dinámico y propio de prevenir la colonización e infección por
organismos patógenos oportunistas. El pH vaginal estable de las
mujeres en etapa reproductiva se mantiene gracias a los estrógenos, el
glucógeno y los lactobacilos, debido a su producto de ácido láctico.
Dichos lactobacilos favorecen la respuesta inmunitaria y combaten la
colonización del epitelio periureteral por uropatógenos.
Este ecosistema vaginal se puede alterar por diversos mecanismos
intrínsecos del húesped o por factores externos como la ingesta de
antibióticos, prácticas intravaginales, alimentación o tabaco.
La importancia de mantener un ecosistema vaginal estable radica en
evitar las infecciones vaginales y sus eventuales complicaciones.
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Amabebe E, Anumba DOC. Psychosocial Stress, Cortisol Levels, and Maintenance of Vaginal Health. Frontiers in Endocrinology. 2018 09 24;9. https://doi.org/10.3389/fendo.2018.00568
Hickey R, Abdo Z, Zhou X, Nemeth K, Hansmann M, Osborn T, Wang F, Forney L. Effects of tampons and menses on the composition and diversity of vaginal microbial communities over time. BJOG: An International Journal of Obstetrics & Gynaecology. 2013 02 11;120(6):695-706. https://doi.org/10.1111/1471-0528.12151
Brotman RM, He X, Gajer P, Fadrosh D, Sharma E, Mongodin EF, Ravel J, Glover ED, Rath JM. Association between cigarette smoking and the vaginal microbiota: a pilot study. BMC Infectious Diseases. 2014 08 28;14(1). https://doi.org/10.1186/1471-2334-14-471
Neggers YH, Nansel TR, Andrews WW, Schwebke JR, Yu K, Goldenberg RL, Klebanoff MA. Dietary Intake of Selected Nutrients Affects Bacterial Vaginosis in Women. The Journal of Nutrition. 2007 09 01;137(9):2128-2133. https://doi.org/10.1093/jn/137.9.2128
Miller EA, Beasley DE, Dunn RR, Archie EA. Lactobacilli Dominance and Vaginal pH: Why Is the Human Vaginal Microbiome Unique?. Frontiers in Microbiology. 2016 Dec 08;7. https://doi.org/10.3389/fmicb.2016.01936
Kenyon C, Colebunders R, Crucitti T. The global epidemiology of bacterial vaginosis: a systematic review. American Journal of Obstetrics and Gynecology. 2013 Dec;209(6):505-523. https://doi.org/10.1016/j.ajog.2013.05.006
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