2018, Número 3
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Dermatología Cosmética, Médica y Quirúrgica 2018; 16 (3)
Reticulohistocitosis multicéntrica. Presentación de un caso clínico de larga evolución y revisión de la literatura
Cetina MJA, Cerón EJD, Torres GE
Idioma: Español
Referencias bibliográficas: 26
Paginas: 215-218
Archivo PDF: 201.34 Kb.
RESUMEN
La reticulohistiocitosis multicéntrica (RHM) es una enfermedad
poco frecuente, de etiología desconocida, su característica histológica
es el depósito de histiocitos en diferentes órganos y tejidos.
Las características clínicas sobresalientes son las lesiones cutáneas
de aspecto nodular y el daño articular (artropatía destructiva).
Se presenta el caso de un varón de 68 años diagnosticado
a la edad de 37 años, tratado de manera inicial con ciclofosfamida,
vincristina y corticosteroides durante un año, logrando
la remisión. Presentó recidiva 27 años después, secundario a
cirugía de reemplazo de cadera por coxartrosis y tratado con
prednisona, metotrexato y aines, con desaparición de las manifestaciones
cutáneas.
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