Vázquez MCA, Alarcón RJJ, Linares NF

Idioma: Español
Referencias bibliográficas: 41
Paginas: 209-218
Archivo PDF: 380.86 Kb.

RESUMEN

Los bloqueadores neuromusculares facilitan intubación endotraqueal, manejo invasivo de vía aérea y relajación transoperatoria. El bloqueo neuromuscular residual es un problema frecuente y poco detectado en la Unidad de Cuidados Postanestésicos. El tren de cuatro es un método útil de monitorización neuromuscular. El objetivo del estudio fue realizar una evaluación económica de sugammadex versus neostigmina/atropina. Material y métodos: Estudio observacional, prospectivo, en pacientes de cirugía laparoscópica electiva bajo anestesia general con rocuronio, realizando reversión neuromuscular en bloqueo moderado (TOF ‹ 0.9). Grupo 1 (n = 30) sugammadex a 2 mg/kg, grupo 2 (n = 30) neostigmina a 0.04 mg/kg y atropina a 0.15 mg/kg. Resultados: Sugammadex tardó 1.4 minutos en alcanzar TOFr › 90% y neostigmina 15.42 minutos (p = 0.00), encontrando ahorro de tiempo en sala de operaciones de 14.01 minutos. En UCPA, sugammadex presentó tiempo de estancia promedio de 52.03 minutos y neostigmina de 68.90 minutos, ahorrando 16.87 minutos (p = 0.0002). El ahorro de costo por fracción de tiempo en quirófano fue de $1,343.5 pesos y en UCPA de $2,760.50 pesos. Conclusiones: Sugammadex presenta diferencia significativa del tiempo ahorrado en sala de operaciones, pero no en el costo. Su uso en quirófano permite obtener ahorro en tiempo de estancia y costo a su egreso de UCPA, compensando el costo del medicamento.

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