García MCM, Favila HR, Porras JMA, Elías PB, Ramos DLR

Idioma: Español
Referencias bibliográficas: 15
Paginas: 315-322
Archivo PDF: 163.62 Kb.

RESUMEN

Objetivo: Comparar el efecto de Gd-DTPA y Gd-DO3A-butrol a diferentes volúmenes en la relación contraste-ruido y señal-ruido de los estudios de Angio-Resonancia Magnética Contrastada (ARM-C) de troncos supra-aórticos.
Material y Métodos: Se realizaron ARM-C de troncos supra-aórticos a 45 pacientes. Cada uno de los pacientes fue asignado aleatoriamente a uno de los tres diferentes grupos: Grupo Mag20: 20 mL de Gd-DTPA a 1.8 mL /s; Grupo Gad20: 20 mL de Gd-DO3A-butrol a 1.8 mL /s; Grupo Gad10: 10 mL de Gd-DO3A-butrol a 0.9 mL /s.
Resultados: El análisis demostró una mayor relación C:R y S:R al utilizar Gd-DTPA a 20 mL comparado con Gd-DO3A-butrol al mismo volumen. Sin embargo, al utilizar Gd-DO3A-butrol a 10 mL se observó una mayor relación C:R comparado tanto con Gd-DO3A-butrol a 20 mL como con Gd-DTPA.
Conclusiones: La relación C:R en ARM-C de troncos supra-aórticos es mayor al utilizar Gd-DO3A-butrol a volúmenes de 10 mL probablemente debido a que existe menor destrucción de la señal por el efecto T₂*.

REFERENCIAS (EN ESTE ARTÍCULO)

1. Prince MR, Yucel EK, Kaufman JA, Harrison DC, Geller SC. Dynamic Gadolinium-enhanced three-dimensional abdominal MR arteriography J Magn Reson Imaging 1993; 3: 877-81.

2. Randoux B, et al, Carotid Artery Stenosis: Prospective Comparison of CT, Three-dimensional Gadolinium-enhanced MR, and Conventional Angiography. Radiology 2001; 220: 179-85.

3. Von Tengg-obligk H, Floemer F, Knopp MV Multiphasic MR Angiography as an intra-individual comparison between the contrast agents Gd-DTPA, Gd-BOPTA and Gd-BT-DO3A. Radiologe 2003; 43: 171-8.

4. Volk M, Strotzer M, Lenhart M, et al. Renal time-resolved MR angiography: Quantitative comparison of gadobenate dimeglumine and gadopentate dimeglumine with different doses. Radiology 2001; 220: 284-488

5. Goyen M, Lauenstein TC, Herborn Cu, Debatin JF, Bosk S. Ruehm SG 0.5M Gd chelate (Magnevist) versus 1.0 M Gd chelate (Gadovist): dose-independent effect on image quality of pelvic three-dimensional MR-angiography. Invest Radiol 2003; 38: 27-33.

6. Wilman AH, Riederer SJ, King BF, et al. Fluoroscopically triggered contrast enhanced three-dimensional MR angiography with elliptical centric view order: Application to the renal arteries. Radiology 1997; 205: 137-46.

7. Ho VB, Foo Tk, Czum JM, et al. Contrast-enhanced magnetic resonance angiography: Technical considerations for optimized clinical implementation. Top Magn Reson Imaging 2001; 12: 283-99.

8. Levy RA, Prince MR, Arterial-phase three-dimensional contrast-enhanced MR angiography of the carotid artery. AJR Am J Roentgenol 1996; 167: 211-15.

9. Leclerc X, Gauvrit YJ, Nicol L, Pruvo JP. Contrast-enhanced MR angriography of the craniocervical vessels: A review. Neuroradiology 1999; 41: 867-74.

10. Cloft HJ, Murphy KJ, Prince MR. Brunberg JA. 3D gadolinium enhanced MR angiography of the carotid arteries. Magn Reson Imaging 1996; 14: 593-600.

11. Bluemke D, et al. Carotid MR Angiography: Phase II Study of Saftey and Efficacy of MS-325d1. Radiology 2001; 219: 114-22.

12. Weinman HJ, et al. Comparative Studies on the Efficacy of MRI Contrast Agents in MRA. Acad Radiol 2002; 9(Suppl. 1): S135-S136.

13. Tombac B, Heindel W. Vaule of 1.0-M gadolinium chelates: Review of preclinical and clinical data on gadobutrol. Eur Radiol 2002; 12: 1550-6.

14. Staks T, Schuhmann-Giampieri G, Frenzel T, Weinmann HJ, Lange L, Platzek J. Pharmacokinetics, dose proportionality, and tolerability of gadobutrol after single intravenous injection in healthy volunteers, Invest Radiol 1994; 29: 709-15.

15. Fink C, Bock M, Kiessling F, et al. Timjjje –Resolved Contrast-Enhanced Three-Dimensional Pulmonary MR-Angiography: 1.0 M Gadobutrol vs. 0.5 M Gadopentate Dimeglumine, J Magnetic Resonance Imaging 2004; 19: 202-8