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Centro Universitario de Ciencias de la Salud de la Universidad de Guadalajara y del OPD Hospitales Civiles de Guadalajara

2005, Número 1

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Inv Salud 2005; 7 (1)


La expresión de marcadores de superficie celular de sangre periférica de sujetos sanos no cambia con la edad

Guerrero VC, Alfaro BF, Sotelo OA, Reyes MME, Santoscoy TL, Fafutis MM

Idioma: Español
Referencias bibliográficas: 36
Paginas: 28-37
Archivo PDF: 452.61 Kb.


RESUMEN

Existe una opinión general sobre la disminución de la respuesta inmune en el envejecimiento. Sin embargo, dicha opinión se basa en un número limitado de estudios sobre porcentajes de subpoblaciones de linfocitos y niveles de citocinas en unos pocos individuos. Aun en la actualidad, los datos son controvertidos. Tratando de dilucidar sobre este problema, estudiamos subtipos de poblaciones en linfocitos de 101 sujetos sanos clasificados de acuerdo al protocolo de SENIEUR, entre 0 y 102 años de edad. Marcadores de linaje y de función se estudiaron cuidadosamente por citometria de flujo. Los resultados analizados por el Coeficiente de Correlación de Pearson sugieren que las funciones inmunes estudiadas no disminuyen con el progreso de la edad.


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