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2013, Número 3

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Med Sur 2013; 20 (3)


Linfoma de la zona marginal, tres enfermedades bajo un mismo nombre: presentación de dos casos y revisión de la literatura

Sarmiento-Chavero M, Lavenant I, Romero-Bañuelos E, Lara-Reyes A

Idioma: Español
Referencias bibliográficas: 52
Paginas: 176-182
Archivo PDF: 349.62 Kb.


RESUMEN

El linfoma de la zona marginal es un conjunto de neoplasias con tres subtipos establecidos: nodal, extranodal y esplénico; cada uno con características histopatológicas, citogenéticas y clínicas propias. El día de hoy se considera al linfoma de Hodgkin como la neoplasia con un mejor pronóstico en los últimos 10 años, llegando a ser una enfermedad controlable casi en su totalidad. El subtipo esplénico es el más raro de esta clase de linfomas, siendo ‹ 1% de todos los linfomas no Hodgkin. Se presenta el caso de una paciente de 64 años de edad, cuya manifestación más importante era dolor abdominal, se realizó tomografía axial computarizada simple que reveló esplenomegalia de 22 cm en su diámetro mayor. Por otro lado, el subtipo nodal se caracterizó por una localización primaria en ganglios linfáticos en ausencia de infiltración a otros órganos. Se presenta el caso de un paciente masculino de 56 años de edad con manifestaciones de sinusitis crónica, se realizó tomografía axial computarizada simple de cráneo en donde se identificó un tumor de 4 x 2 cm localizado en el seno maxilar derecho. El extra nodal asociado a tejido linfoide asociado a mucosas, es el más común de los tres y está muy relacionado con ciertas infecciones como Helicobacter pylori en linfoma primario gástrico y enfermedades inflamatorias crónicas.


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