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2018, Número 1

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Med Crit 2018; 32 (1)


Asociación entre el nivel de cortisol sérico y la mortalidad en pacientes postquirúrgicos con choque hipovolémico hemorrágico

Díaz GSP, Sánchez DJS, Martínez REA, García MRC, Peniche MKG, Calyeca SMV

Idioma: Español
Referencias bibliográficas: 33
Paginas: 7-12
Archivo PDF: 210.84 Kb.


RESUMEN

Introducción: El uso de corticosteroides para el tratamiento de pacientes con choque séptico ha llevado a considerar su empleo en otros procesos patológicos, entre ellos, el choque hipovolémico hemorrágico, aunque con resultados controversiales.
Material y métodos: Se realizó un estudio de cohorte, prospectivo, longitudinal, observacional y analítico. Se incluyeron pacientes ingresados a la Unidad de Cuidados Intensivos (UCI) con diagnóstico de choque hipovolémico hemorrágico secundario a evento quirúrgico en el periodo comprendido entre el 1 de enero y el 31 de julio de 2017.
Resultados: Por medio de la curva ROC se estableció el punto de corte para el cortisol sérico al ingreso a la UCI, estimado en 39.1 µg/dL, con área bajo la curva de 1.00 (IC95% 0.0012-0.2487, p = 0.0001). La sensibilidad fue de 100%, con especificidad de 100%; los coeficientes de probabilidad positivo y negativo fueron de 14 y cero, respectivamente.
Conclusión: Los niveles de cortisol sérico medidos al ingreso a la UCI superiores a 39.1 µg/dL se asocian con mayor mortalidad en los pacientes postquirúrgicos con choque hipovolémico hemorrágico.


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