2018, Número 1
<< Anterior Siguiente >>
An Med Asoc Med Hosp ABC 2018; 63 (1)
La unidad de dolor torácico en el servicio de urgencias y el uso de la escala PRETEST y troponina I ultrasensible. Nuevo abordaje con una vieja herramienta
Pérez CJA, Mérigo AC, Montoya GC, Hernández FKS
Idioma: Español
Referencias bibliográficas: 22
Paginas: 14-19
Archivo PDF: 223.55 Kb.
RESUMEN
Introducción: Las unidades de dolor torácico son una herramienta útil en urgencias; su objetivo principal es la admisión fácil y expedita de los pacientes. Las escalas de riesgo PRETEST son evaluaciones que detectan pacientes con bajo riesgo de padecer un síndrome coronario.
Objetivos: Determinar la efectividad de la escala de riesgo PRETEST y troponina I como rule-out (descarte) para detectar a pacientes con bajo riesgo de síndrome coronario agudo.
Material y métodos: Fueron evaluados pacientes con dolor torácico en el Servicio de Urgencias del Centro Médico ABC; se obtuvieron datos como tipo de dolor, edad, género y troponina. Utilizando el formato de «unidad de dolor torácico», se determinó la escala PRETEST y troponina I. Se consultó el sistema TIMSA/ONBASE para confirmar diagnósticos y se calcularon la sensibilidad, especificidad, valor predictivo positivo, valor predictivo negativo y riesgo relativo.
Resultados: Se evaluaron 114 pacientes, 75.4% fueron hombres y 24.6% mujeres; 21.9% se presentaron con dolor típico. La escala PRETEST tuvo una sensibilidad de 38%, con una especificidad de 93.8%, un valor predictivo positivo de 82.6% y un valor predictivo negativo de 65.9%, con una p ‹ 0.05. El acumulado de troponina I y PRETEST tuvo una especificidad del 100%.
Conclusiones: La escala PRETEST representa una ventaja en la evaluación de pacientes con dolor torácico y sospecha de síndrome coronario agudo.
REFERENCIAS (EN ESTE ARTÍCULO)
Kontos MC, Diercks DB, Kirk JD. Emergency department and office-based evaluation of patients with chest pain. Mayo Clin Proc. 2010; 85 (3): 284-299.
Ayerbe L, González E, Gallo V, Coleman CL, Wragg A, Robson J. Clinical assessment of patients with chest pain; a systematic review of predictive tools. BMC Cardiovasc Disord. 2016; 16: 18.
Gibbons RJ, Chatterjee K, Daley J, Douglas JS, Fihn SD, Gardin JM et al. ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina: executive summary and recommendations. A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Chronic Stable Angina). Circulation. 1999; 99 (21): 2829-2848.
Wolk MJ, Bailey SR, Doherty JU, Douglas PS, Hendel RC, Kramer CM et al. ACCF/AHA/ASE/ASNC/HFSA/HRS/SCAI/SCCT/SCMR/STS 2013 multimodality appropriate use criteria for the detection and risk assessment of stable ischemic heart disease: a report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Failure Society of America, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and Society of Thoracic Surgeons. J Am Coll Cardiol. 2014; 63 (4): 380-406.
Wechkunanukul K, Grantham H, Clark RA. Global review of delay time in seeking medical care for chest pain: an integrative literature review. Aust Crit Care. 2017; 30 (1): 13-20.
Thygesen K, Alpert JS, Jaffe AS, Simoons ML, Chaitman BR, White HD et al. Third universal definition of myocardial infarction. Circulation. 2012; 126 (16): 2020-2035.
Smulders MW, Kietselaer BL, Schalla S, Bucerius J, Jaarsma C, van Dieijen-Visser MP et al. Acute chest pain in the high-sensitivity cardiac troponin era: A changing role for noninvasive imaging? Am Heart J. 2016; 177: 102-111.
Storrow AB, Christenson RH, Nowak RM, Diercks DB, Singer AJ, Wu AH et al. Diagnostic performance of cardiac troponin I for early rule-in and rule-out of acute myocardial infarction: Results of a prospective multicenter trial. Clin Biochem. 2015; 48 (4-5): 254-259.
Eggers KM, Johnston N, James S, Lindahl B, Venge P. Cardiac troponin I levels in patients with non-ST-elevation acute coronary syndrome —the importance of gender. Am Heart J. 2014; 168 (3): 317-324.e1.
Korley FK, Schulman SP, Sokoll LJ, DeFilippis AP, Stolbach AI, Bayram JD et al. Troponin elevations only detected with a high-sensitivity assay: clinical correlations and prognostic significance. Acad Emerg Med. 2014; 21 (7): 727-735.
Bittencourt MS, Hulten E, Polonsky TS, Hoffman U, Nasir K, Abbara S et al. European Society of Cardiology —Recommended Coronary Artery Disease Consortium Pretest Probability Scores more accurately predict obstructive coronary disease and cardiovascular events than the Diamond and Forrester Score: The Partners Registry. Circulation. 2016; 134 (3): 201-211.
Demarco DC, Papachristidis A, Roper D, Tsironis I, Byrne J, Alfakih K et al. Pre-test probability risk scores and their use in contemporary management of patients with chest pain: One year stress echo cohort study. JRSM Open. 2015; 6 (11): 2054270415611295.
Bassan R. Chest pain units: a modern way of managing patients with chest pain in the emergency department. Arq Bras Cardiol. 2002; 79 (2): 196-209.
Quin G. Chest pain evaluation units. J Accid Emerg Med. 2000; 17 (4): 237-240.
Than M, Cullen L, Aldous S, Parsonage WA, Reid CM, Greenslade J et al. 2-Hour accelerated diagnostic protocol to assess patients with chest pain symptoms using contemporary troponins as the only biomarker: the ADAPT trial. J Am Coll Cardiol. 2012; 59 (23): 2091-2098.
Cullen L, Mueller C, Parsonage WA, Wildi K, Greenslade JH, Twerenbold R et al. Validation of high-sensitivity troponin I in a 2-hour diagnostic strategy to assess 30-day outcomes in emergency department patients with possible acute coronary syndrome. J Am Coll Cardiol. 2013; 62 (14): 1242-1249.
Reichlin T, Cullen L, Parsonage WA, Greenslade J, Twerenbold R, Moehring B et al. Two-hour algorithm for triage toward rule-out and rule-in of acute myocardial infarction using high-sensitivity cardiac troponin T. Am J Med. 2015; 128 (4): 369-379.e4.
Eggers KM, Aldous S, Greenslade JH, Johnston N, Lindahl B, Parsonage WA et al. Two-hour diagnostic algorithms for early assessment of patients with acute chest pain —Implications of lowering the cardiac troponin I cut-off to the 97.5th percentile. Clin Chim Acta. 2015; 445: 19-24.
Boeddinghaus J, Reichlin T, Cullen L, Greenslade JH, Parsonage WA, Hammett C et al. Two-hour algorithm for triage toward rule-out and rule-in of acute myocardial infarction by use of high-sensitivity cardiac troponin I. Clin Chem. 2016; 62 (3): 494-504.
Carlton EW, Khattab A, Greaves K. Identifying patients suitable for discharge after a single-presentation high-sensitivity troponin result: a comparison of five established risk scores and two high-sensitivity assays. Ann Emerg Med. 2015; 66 (6): 635-645.e1.
Herren KR, Mackway-Jones K. Emergency management of cardiac chest pain: a review. Emerg Med J. 2001; 18 (1): 6-10.
Borrás-Pérez FX. Diagnóstico y estratificación de la angina estable. Rev Esp Cardiol Supl. 2012; 12: 9-14.