2017, Número 1
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Rev Mex Invest Psic 2017; 9 (1)
Evidencia de procesos asociativos en la extinción de la memoria espacial en humanos
Luna D, Manzanares-Silva M, Rodríguez-González K, López-Cruz H
Idioma: Español
Referencias bibliográficas: 67
Paginas: 1-14
Archivo PDF: 446.15 Kb.
RESUMEN
Se investigó la participación de procesos asociativos en la extinción
de la memoria espacial en humanos. Tres grupos de
participantes fueron entrenados para aprender la localización
de una plataforma oculta, cuya ubicación fue señalada por
un conjunto de claves distales. Durante un ensayo de prueba
sin plataforma, los grupos mostraron una preferencia por el
cuadrante reforzado, la cual fue disminuyendo gradualmente
y sin diferencias entre ellos. La pérdida de dicha preferencia
se ajustó adecuadamente a una función exponencial. Esto es
consistente con un efecto de extinción, el cual ocurrió tal y
como lo predicen algunos modelos de aprendizaje asociativo.
Se discuten las implicaciones teóricas y aplicadas de dicho
resultado.
REFERENCIAS (EN ESTE ARTÍCULO)
Amsel, A. (1962). Frustrative nonreward in partial reinforcement and discrimination learning: Some recent history and a theoretical extinction. Psychological Review, 69, 306-328. doi: 10.1037/h0046200.
Aron. A., & Aron, E. N. (2001). Estadística para psicólogos. México: Prentice Hall.
Astur, R. S., Purton, A. J., Zaniewski, M. J., Cimadevilla, J., & Markus, E. J. (2016). Human sex differences in solving a virtual navigation problem. Behavioural Brain Research, 308, 236-243. doi: 10.1016/j.bbr.2016.04.037.
Astur, R. S., Taylor, L. B., Mamelak, A. N., Philpott, L., & Sutherland, R. J. (2002). Humans with hippocampus damage display severe spatial memory impairments in a virtual Morris water task. Behavioral Brain Research, 132, 77-84. doi: http://dx.doi.org/10.1016/S0166-4328(01)00399-0.
Ayaz, H., Shewokis, P. A., Curtin, A., Izzetoglu, M., Izzetoglu, K., & Onaral, B. (2011). Using maze suite and functional near infrared spectroscopy to study learning in spatial navigation. Journal of Visualized Experiments, 56, e3443. doi: 10.3791/3443.
Beatty, W. W., & O’Briant, D. A. (1973). Sex differences in extinction of food-rewarded approach responses. Bulletin of the Psychonomic Society, 2, 97-98. doi: 10.3758/BF03327728.
Blaser, R., & Bellizzi, C. (2014). The comparative study of learning from 1994-2013. International Journal of Comparative Psychology, 27, 31-49.
Blokland, A., Geraerts, E., & Been, M. (2004). A detailed analysis of rats’ spatial memory in a probe trial of a Morris task. Behavioural Brain Research, 154, 71-75. doi: 10.1016/j. bbr.2004.01.022
Brandner, E. (2007). Strategy selection during exploratory behavior: sex differences. Judgment and Decision Making, 2, 326-332.
Bremner, J. D., Vermetten, E. V., Afzal, N., & Vythilingam, M. (2004). Deficits in verbal declarative memory function in women with childhood sexual abuse-related posttraumatic stress disorder. The Journal of Nervous and Mental Disease, 192, 643-649. doi: 10.1097/01.nmd.0000142027.52893.c8.
Chamizo, V. D. (2002). Spatial learning: Conditions and basic effects. Psicológica, 23, 33-57.
Chamizo, V. D., Artigas, A. A., Sansa, J., & Banterla, F. (2011). Gender differences in landmark learning for virtual navigation: The role of distance to a goal. Behavioral Processes, 88, 20-26. doi: http://dx.doi.org/10.1016/j.beproc. 2011.06.007.
Conejo, N. M., Gonzalez-Pardo, H., Vallejo, G., & Arias, J. L. (2007). Changes in brain oxidative metabolism induced by water maze training. Neuroscience, 145, 403-412. doi: 10.1016/j.neuroscience.2006.11.057.
Craske, M. G. (2015). Optimizing exposure therapy for anxiety disorders: an inhibitory learning and inhibitory regulation approach. Verhaltenstherapie, 25, 134-143. doi: 10.1159/000381574.
Culver, N. C., Vervliet, B., & Craske, M. G. (2015). Compound extinction using the Rescorla–Wagner model to maximize exposure therapy effects for anxiety disorders. Clinical Psychological Science, 3, 335-348. doi: 10.1177/2167702614542103.
Delamater, A. R. (2004). Experimental extinction in Pavlovian conditioning: Behavioural and neuroscience perspectives. Quarterly Journal of Experimental Psychology Section B, 57, 97-132. doi: 10.1080/02724990344000097.
Delamater, A. R., & Westbrook, R. F. (2014). Psychological and neural mechanisms of experimental extinction: A selective review. Neurobiology of Learning and Memory, 108, 38-51. doi:http://dx.doi.org/10.1016/j.nlm.2013.09.016.
Devenport, L. D. (1984). Extinction-induced spatial dispersion in the radial arm maze: arrest by ethanol. Behavioral Neuroscience, 98, 979-985. doi:http://dx.doi.org/10.1037/0735- 7044.98.6.979
Dickinson, A. (1980). Contemporary animal learning theory. Cambridge: Cambridge University Press.
Dunsmoor, J. E., Niv, Y., Daw, N., & Phelps, E. A. (2015). Rethinking extinction. Neuron, 88, 47-63. doi: 10.1016/j.neuron. 2015.09.028
Ehlers, A., & Clark, D. M. (2000). A cognitive model of posttraumatic stress disorder. Behaviour Research and Therapy, 38, 319-345. doi: 10.1016/S0005-7967(99)00123-0.
Forcano, L., Santamaría, J., Mackintosh, N. J., & Chamizo, V. D. (2009). Single landmark learning in rats: Sex differences in a navigation task. Learning and Motivation, 40, 46-61. doi: http://dx.doi.org/10.1016/j.lmot.2008.05.003.
Goodrich-Hunsaker, N. J., Livingstone, S. A., Skelton, R. W., & Hopkins, R. O. (2009). Spatial deficits in a virtual water maze in amnesic participants with hippocampal damage. Hippocampus, 20, 481-491. doi: 10.1002/hipo.20651.
Guo, R., Liang, N., Tai, F. D., Wu, R. Y., Chang, G., He, F. Q., & Yuan, Q. W. (2011). Differences in spatial learning and memory for male and female mandarin voles (Microtus mandarinus) and BALB/c mice. Zoological Studies, 50, 24-30.
Hardt, O., Hupbach, A., & Nadel, L. (2009). Factors moderating blocking in human place learning: The role of task instructions. Learning & Behavior, 37, 42-59. doi: 10.3758/ LB.37.1.42.
Ishida, M., & Papini, M. R. (1997). Massed trial overtraining effects on extinction and reversal performance in turtles (Geoclemys reevesii). The Quarterly Journal of Experimental Psychology: Section B, 50, 1-16. doi: 10.1080/027249997393619.
Jacobs, W. J., Laurance, H. E., & Thomas, K. G. (1997). Place learning in virtual space I: Acquisition, overshadowing, and transfer. Learning and Motivation, 28, 521-541. doi: 10.1006/lmot.1997.0977.
Jones, C. M., & Healy, S. D. (2006). Differences in cue use and spatial memory in men and women. Proceedings of the Royal Society of London B: Biological Sciences, 273, 2241-2247. doi: 10.1098/rspb.2006.3572.
Kelly, D. M., & Gibson, B. M. (2007). Spatial navigation: Spatial learning in real and virtual environments. Comparative Cognition & Behavior Reviews, 2, 11-124, doi: http://dx.doi. org/10.3819/ccbr.2008.20007.
Kolarik, B. S., Shahlaie, K., Hassan, A., Borders, A. A., Kaufman, K. C., Gurkoff, G., & Ekstrom, A. D. (2016). Impairments in precision, rather than spatial strategy, characterize performance on the virtual Morris Water Maze: A case study. Neuropsychologia, 80, 90-101. doi: 10.1016/j.neuropsychologia. 2015.11.013.
Lattal, K. M., & Abel, T. (2001). Different requirements for protein synthesis in acquisition and extinction of spatial preferences and context-evoked fear. The Journal of Neuroscience, 21, 5773-5780.
Lattal, K. M., & Lattal, K. A. (2012). Facets of Pavlovian and operant extinction. Behavioural Processes, 90, 1-8. doi: 10.1016/j.beproc.2012.03.009.
Lattal, K. M., Mullen, M. T., & Abel, T. (2003). Extinction, renewal and spontaneous recovery of a spatial preference in the water maze. Behavioral Neuroscience, 117, 1017-1028. doi: http://dx.doi.org/10.1037/0735-7044.117.5.1017.
Leising, K. J., & Blaisdell, A. P. (2009). Associative basis of landmark learning and integration in vertebrates. Comparative Cognition & Behavior Reviews, 4, 80-102. doi: 10.3819/ ccbr.2009.40010.
Luna, D., & Martínez, H. (2015). Spontaneous recovery of human spatial memory in a virtual water maze. Psicológica, 36, 283-308.
Luna, D., Alvarado, A., & Vila, J. (2013). Influencia del sexo en la interferencia y renovación contextual del aprendizaje espacial en humanos. Journal of Behavior, Health & Social Issues, 5, 55-66. doi: http://dx.doi.org/10.5460/jbhsi.v5.1.38726.
Mackintosh, N. J. (1975). A theory of attention: variations in the associability of stimuli with reinforcement. Psychological Review, 82, 276. doi:http://dx.doi.org/10.1037.
Méndez-Couz, M., Conejo, N. M., Vallejo, G., & Arias, J. L. (2015). Brain functional network changes following prelimbic area inactivation in a spatial memory extinction task. Behavioural Brain Research, 287, 247-255. doi: 10.1016/j. bbr.2015.03.033.
Méndez-Couz, M., Conejo, N. M., Vallejo, G., & Arias, J. L., (2014). Spatial memory extinction: A c-Fos protein mapping study. Behavioural Brain Research, 260, 101-110. doi: http://dx.doi.org/10.1016/j.bbr.2013.11.032.
Mizumori, S. J., Puryear, C. B., & Martig, A. K. (2009). Basal ganglia contributions to adaptive navigation. Behavioural Brain Research, 199, 32-42. doi: 10.1016/j.bbr.2008.11.014.
Morellini, F. (2013). Spatial memory tasks in rodents: What do they model? Cell Tissue Research, 354, 273-286. doi: 10.1007/s00441-013-1668-9.
Morris, R. (2013). Neurobiology of Learning and Memory. En D. W. Pfaff (Ed.), Neuroscience in the 21st Century (pp. 2173-2211). New York: Springer.
Morris, R. G. M. (1984). Developments of a water-maze procedure for studying spatial learning in the rat. Journal of Neuroscience Methods, 11, 47-60. doi: http://dx.doi. org/10.1016/0165-0270(84)90007-4.
Moussa, R., Poucet, B., Amalric, M., & Sargolini, F. (2011). Contributions of dorsal striatal subregions to spatial alternation behavior. Learning & Memory, 18, 444-451. doi: 10.1101/lm.2123811.
North, A. J., & Stimmel, D. T. (1960). Extinction of an instrumental response following a large number of reinforcements. Psychological Reports, 6, 227-234. doi: 10.2466/ pr0.1960.6.2.227.
O’Keefe, J., & Nadel, L. (1978). The hippocampus as a cognitive map. Oxford: Clarendon Press.
Pacheco-Cobos, L., Rosetti, M., Cuatianquiz, C., & Hudson, R. (2010). Sex differences in mushroom gathering: Men expend more energy to obtain equivalent benefits. Evolution and Human Behavior, 31, 289-297. doi: 10.1016/j.evolhumbehav. 2009.12.008.
Pearce, J. M., & Hall, G. (1980). A model for Pavlovian learning: Variations in the effectiveness of conditioned but not of unconditioned stimuli. Psychological Review, 87, 532-552. doi: http://dx.doi.org/10.1037/0033-295X.87.6.532.
Pickering, A. D., Díaz, A., & Gray, J. A. (1995). Personality and reinforcement: an exploration using a maze-learning task. Personality and Individual Differences, 18, 541-58. doi: 10.1016/0191-8869(94)00182-R.
Porte, Y., Trifilieff, P., Wolff, M., Micheau, J., Buhot, M. C., & Mons, N. (2011). Extinction of spatial memory alters CREB phosphorylation in hippocampal CA1. Hippocampus, 21, 1169-1179. doi: 10.1002/hipo.20844.
Prados, J., Manteiga, D., & Sansa, J. (2003). Recovery effects after extinction in the Morris swimming pool navigation task. Learning & Behavior, 31, 299-304. doi: 10.3758/ BF03195991.
Prados, J., Sansa, J., & Artigas, A. A. (2008). Partial reinforcement effects on learning and extinction of place preferences in the water maze. Learning & Behavior, 36, 311-318. doi: 10.3758/LB.36.4.311.
Rescorla, R. A., & Wagner, A. (1972). A theory of pavlovian conditioning: Variations in the effectiveness of reinforcement and nonreinforcement. En A. Black & W. Prokasy (Eds.), Classical conditioning II: Current research and theory (pp. 64- 99). New York: Appleton-Century-Crofts.
Rossato, J. I., Bevilaqua, L. R. M., Medina, J. H., Izquierdo, I., & Cammarota, M., (2006). Retrieval induces hippocampal- dependent reconsolidation of spatial memory. Learning & Memory, 13, 431-440. doi: 10.1101/lm.315206.
Sánchez-Carrasco, L., & Nieto, J. (2009). Recuperación de respuestas: una revisión de la evidencia y del modelo de recuperación de información. Revista Mexicana de Análisis de la Conducta, 35, 45-59.
Sandstrom, N. J., Kauffman, J., & Huettel, S. A. (1998). Males and females use different distal cues in a virtual environ ment navigation task. Cognitive Brain Research, 6, 351-360. doi: http://dx.doi.org/10.1016/S0926-6410(98)00002-0.
Schoenfeld, R., Foreman, N., & Leplow, B. (2014). Ageing and spatial reversal learning in humans: Findings from a virtual water maze. Behavioural Brain Research, 270, 47-55. doi: 10.1016/j.bbr.2014.04.036
Schulz, D., Houston, J. P., Buddenberg, T., & Topic, B. (2007). “Despair” induced by extinction trials in the water maze: Relationship with measures of anxiety in aged and adult rats. Neurobiology of Learning and Memory, 87, 309-323. doi: 10.1016/j.nlm.2006.09.006.
Schulz, D., Topic, B., De Souza Silva, M. A., & Huston, J. P. (2004). Extinction-induced immobility in the water maze and its neurochemical concomitants in aged and adult rats: A possible model for depression? Neurobiology of Learning and Memory, 82, 128-141. doi: 10.1016/j.nlm.2004.05.010.
Shettleworth, S. J. (2010). Cognition, evolution and behavior. New York: Oxford University Press.
Spieker, E. A., Astur, R. S., West, J. T., Griego, J. A., & Rowland, L. M. (2012). Spatial memory deficits in a virtual reality eight-arm radial maze in schizophrenia. Schizophrenia Research, 135, 84-89. doi: 10.1016/j.schres.2011.11.014.
Spooner, R. I. W., Thomson, A., Hall, J., Morris, R. G. M., & Salter, S. H. (1994). The Atlantis platform: A new design and further developments of Buresova’s on-demand platform for the water maze. Learning & Memory, 1, 203-211. doi:10.1101/lm.1.3.203.
Vargas-López, V., Lamprea, M. R., & Múnera, A. (2011). Characterizing spatial extinction in an abbreviated version of the Barnes maze. Behavioural Processes, 86, 30-38. doi: 10.1016/j.beproc.2010.08.002.
Videlier, M., Cornette, R., Bonneaud, C., & Herrel, A. (2015). Sexual differences in exploration behavior in Xenopus tropicalis? Journal of Experimental Biology, 218, 1733-1739. doi: 10.1242/jeb.120618.
Vorhees, C. V., & Williams, M. T. (2006). Morris water maze: procedures for assessing spatial and related forms of learning and memory. Nature Protocols, 1, 848-858. doi: 10.1038/nprot.2006.116.
Vorhees, C. V., & Williams, M. T. (2014). Assessing spatial learning and memory in rodents. ILAR Journal, 55, 310-332. doi: https://doi.org/10.1093/ilar/ilu013.
W. M. A. (World Medical Association Declaration of Helsinki) (2008). Ethical principles for medical research involving human subjects. En World Medical Association. Recuperado de http://www.wma.net/en/30publications/10policies/b3/ index.html.