2017, Número 2
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Rev Med Inst Mex Seguro Soc 2017; 55 (2)
Severidad de la preeclampsia y su relacion con volumen plaquetario y ancho de distribucion eritrocitaria
Viana-Rojas JJ, Rosas-Cabral A, Prieto-Macías J, Terrones-Saldívar MC, Arcos-Noguez P, Bermúdez- Gómez J, Martínez-Padilla LE, Sandoval-Valdez DA, Hernández GF, Serrano-Díaz LC
Idioma: Español
Referencias bibliográficas: 30
Paginas: 176-181
Archivo PDF: 274.15 Kb.
RESUMEN
Introducción: se ha establecido fuertemente la asociación entre el
ancho de distribución eritrocitario (ADE) y el volumen plaquetario medio
(VPM) con la hipertensión arterial sistémica. Sin embargo, se han realizado
pocos estudios en pacientes con preeclampsia, obteniéndose
resultados inconsistentes. Nuestro objetivo es evaluar la relación entre
el ADE y el VPM con la severidad de la preeclampsia.
Métodos: incluimos 64 pacientes con preeclampsia (26 leve, 38 severa)
y 70 pacientes con embarazo normotenso. Los datos clínicos, características
sociodemográficas y valores de laboratorio, incluyendo ADE y
VPM, fueron registrados en cada paciente.
Resultados: las medidas de hemoglobina y conteo plaquetario fueron
similares entre ambos grupos. Las pacientes con preeclampsia tuvieron
niveles de ADE (14.7 ± 1.4 frente a 13.4 ± 0.7,
p = 0.0001) y VPM
(11.8 ± 2.4 frente a 11.0 ± 1.4,
p = 0.03) más elevados que el grupo
control. El subgrupo de preeclampsia severa tuvo niveles más elevados
de ADE (15.0 ± 1.6 frente a 14.0 ± 0.6,
p = 0.001) y VPM (12.7 ± 2.8
frente a 10.8 ± 1.8,
p = 0.01) que las pacientes con preeclampsia leve.
Conclusiones: se demuestra que el ADE y el VPM son medidas accesibles
asociadas a la severidad de la preeclampsia.
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