medigraphic.com
Órgano oficial de la Sociedad Mexicana de Cirugía Dermatológica y Oncológica, AC

2017, Número 1

<< Anterior Siguiente >>

Dermatología Cosmética, Médica y Quirúrgica 2017; 15 (1)


Linfoma extranodal t/nk tipo nasal variante extranasal. Reporte de un caso y revisión de la literatura

López VF, Aquino FC, Sibaja NL, Aquino JMÁ, Toussaint CS, Arenas GR

Idioma: Español
Referencias bibliográficas: 29
Paginas: 22-25
Archivo PDF: 206.69 Kb.


RESUMEN

El linfoma t/nk extranasal es poco frecuente, la presentación clínica es variable. Cuando afecta la piel aparece como placas induradas, neoformaciones nodulares o subcutáneas. El diagnóstico y manejo oportuno son vitales porque se trata de una patología agresiva. Se describe el caso de un hombre de 69 años con dermatosis localizada en el abdomen, constituida por tres neoformaciones cupuliformes, con centro ulcerado y necrosado e infiltración peritumoral. El diagnóstico de linfoma t/nk se realizó por histología e inmunomarcación. Se administraron ocho ciclos de quimioterapia con respuesta clínica completa pero recidiva con progresión a los cuatro meses, causándole la muerte.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. Sareeta R, Parker S, Solomon A y Lane J. Report of Epstein-Barr viruspositive primary cutaneous natural killer/t-cell lymphoma, J Am Acad Dermatol 2008; 59(1): 157-61.

  2. Jo J, Yoon DH, Kim S et al. Clinical features and prognostic model for extranasal nk/t-cell lymphoma, Eur J Haematol 2012; 89(2): 103-10.

  3. Lin N, Song Y, Zheng W et al. A prospective phase ii study of L-asparaginase- chop plus radiation in newly diagnosed extranodal nk/t-cell lymphoma, nasal type, J Hematol Oncol 2013; 6: 44.

  4. Aozasa K y Zaki M. Epidemiology and pathogenesis of nasal nk/t-cell lymphoma: a mini-review, Scientific World Journal 2011; 11: 422-8.

  5. Chan JK, Sin VC, Wong KF et al. Non nasal lymphomas expressing the natural killer cell marker cd56: a clinic pathologic study of 49 cases of uncommon aggressive neoplasm, Blood 1997; 89(12): 4501-13.

  6. Rodrigo JP, Suárez C, Rinaldo A et al. Idiopathic midline destructive disease: factor fiction, Oral Oncol 2005; 41(4): 340-8.

  7. Altemani A, Barbosa AC, Kulka M et al. Characteristics of nasal t/nkcell lymphoma among Brazilians, Neoplasma 2002; 49(1): 55-60.

  8. Arber DA, Weiss LM, Albújar PF et al. Nasal lymphomas in Peru. High incidence of T-cell immunophenotype and Epstein-Barr virus infection, Am J Surg Pathol 1993; 17(4): 392-9.

  9. Jaffe E, Krenacs L y Raffeld M. Classification of cytotoxic t-cell and natural killer cell lymphomas, Semin Hematol 2003; 40(3): 175-84.

  10. Barrionuevo C, Zaharia M, Martínez MT et al. Extranodal nk/t-cell lymphoma, nasal type: study of clinic pathologic and prognosis factors in a series of 78 cases from Peru, Applimmunohistochem Mol Morphol 2007; 15(1): 38-44.

  11. Willemze R, Jaffe E, Burg G et al. who-eortc classification for cutaneous lymphomas, Blood 2005; 105(10): 3768-85.

  12. Rueda J y Cortés C. Linfomas cutáneos, Rev Asoc Col Dermatol 2008; 16(2): 143-58.

  13. Takahashi E, Asano N, Li C et al. Nodal t/nk-cell lymphoma of nasal type: a clinic pathological study of six cases, Histopathology 2008; 52(5): 585-96.

  14. Vázquez A, Khan MN, Blake DM et al. Extranodal natural killer/t-cell lymphoma: a population-based comparison of sinonasal and extranasal disease, Laryngoscope 2014; 124(4): 888-95.

  15. Zhang T, Fu Q, Gao D et al. ebv associated lymphomas in 2008 who classification, Pathol Res Pract 2014; 210(2): 69-73.

  16. Garrido F, Festenstein H y Schirrmacher V. Further evidence for depression of h-2 and Ia-like specificities of foreign haplotypes in mouse tumour cell lines, Nature 1976; 261(5562): 705-7.

  17. Yu JB, Zuo Z, Tang Y et al. Extranodal nasal-type natural killer/t-cell lymphoma of the skin: a clinic pathologic study of 16 cases in China, Hum Pathol 2009; 40(6): 807-16.

  18. Pol-Rodríguez MM, Fox LP, Sulis ML et al. Extranodal nasal-type natural killer T-cell lymphoma in an adolescent from Bangladesh, J Am Acad Dermatol 2006; 54(5 Suppl): S192-7.

  19. Greer JP, Kinney MC y Loughran TP Jr. T-cell and nk-cell lympho proliferative disorders, Hematology Am Soc Hematol Educ Program 2001; 2001(1): 259-81.

  20. Quintanilla-Martínez L, Kremer M, Keller G et al. p53 mutations in nasal. Natural killer/t-cell lymphoma from Mexico, Am J Pathol 2001; 159(6): 2095-105.

  21. Lee J, Suh C, Park YH et al. Extranodal natural killer t-cell lymphoma, nasal-type: a prognostic model from a retrospective multicenter study, J Clin Oncol 2006; 24(4): 612-8.

  22. Anderson JR, Armitage JO y Weisenburger DD. Epidemiology of the non-Hodgkin’s lymphomas: distributions of the major subtypes differ by geographic locations, Ann Oncol 1998; 9(7): 717-20.

  23. Au WY, Weisenburger DD, Intragumtornchai T et al. Clinical differences between nasal and extranasal natural killer/t-cell lymphoma: a study of 136 cases from the International Peripheral t-cell lymphoma Project, Blood 2009; 113(17): 3931-7.

  24. Kojya S, Matsumura J, Ting L et al. Familial nasal nk/t-cell lymphoma and pesticide use, Am J Hematol 2001; 66(2): 145-7.

  25. Waterhouse D, Carman WJ, Schottenfeld D et al. Cancer incidence in the rural community of Tecumseh, Michigan: a pattern of increased lympho poietic neoplasms, Cancer 1996; 77(4): 763-70.

  26. Bajor-Dattilo EB, Pittaluga S y Jaffe ES. Pathobiology of t-cell and nk-cell lymphomas, Best Pract & Res Clin Haematol 2013; 26(1): 75-87.

  27. Lan MX, Zhen ZX y Ming WH. cd56-negative extranodal nasal type of natural killer/t-cell lymphoma with extranasal skin involvement, Leuk Lymphoma 2009; 50(10): 1715-7.

  28. Quintanilla-Martínez L, Franklin JL, Guerrero I et al. Histological and immunophenotypic profile of nasal nk/t-cell lymphomas from Peru: high prevalence of p53 over expression, Hum Pathol 1999; 30(7): 849-55.

  29. Miles RR, Afify Z, Yaish H y Perkins SL. cd56-negative extranodal nasal type nk/t-cell lymphoma, Pediatr Blood Cancer 2010; 55(1): 186-9.




2020     |     www.medigraphic.com