Ramírez MT

Idioma: Ingles.
Referencias bibliográficas: 30
Paginas: 11-16
Archivo PDF: 148.44 Kb.

RESUMEN

El mayor reto en el tratamiento de conductos es lograr disminuir la carga bacteriana a un nivel que nos permita tener éxito en el mismo, así como evitar la reinfección del mismo. Sin embargo, dada la presencia de una biopelícula bacteriana altamente resistente dentro del sistema de conductos y a la incapacidad de los instrumentos y soluciones irrigantes empleados durante la desinfección químico-mecánica de eliminar esta biopelícula, no ha sido posible aumentar el porcentaje de éxito en el tratamiento de conductos, el mismo no ha cambiado en los últimos 50 años. Con este escenario de por medio, el campo de investigación en endodoncia se ha enfocado en la búsqueda de nuevas estrategias de desinfección en la lucha contra la biopelícula bacteriana. Están siendo estudiados desde las soluciones irrigantes convencionales hasta productos de la nanotecnología, múltiples estudios tanto clínicos como in vitro se llevan a cabo día con día en esta incesante búsqueda. Cuál será el siguiente paso, hacia dónde vamos?

REFERENCIAS (EN ESTE ARTÍCULO)

1. Ramachandran Nair P. N., Harndt E., Winkler K., et al. Light and electron microscopic studies of root canal flora and periapical lesions. J. Endod. Elsevier; 1987 Jan; 13 (1): 29–39.

2. Molven O., Olsen I., Kerekes K. Scanning electron microscopy of bacteria in the apical part of root canals in permanent teeth with periapical lesions. Endod Dent Traumatol. 1991 Oct; 7 (5):.226–9.

3. Ricucci D., Siqueira J. F., Lopes WSP, Vieira AR, Rôças I. N. Extraradicular infection as the cause of persistent symptoms: a case series. J Endod. 2015 Feb; 41 (2): 265–73.

4. Siqueira J. F., Rôças I. N., Lopes H. P. Patterns of microbial colonization in primary root canal infections. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002 Feb; 93 (2): 174–8.

5. Sundqvist G. Ecology of the root canal flora. J. Endod. 1992 Sep ;18(9): 427–30.

6. Möller A. J. Microbiological examination of root canals and periapical tissues of human teeth. Methodological studies. Odontol Tidskr. 1966 Dec 20 74 (5): Suppl:1-380.

7. Bergenholtz G. Micro-organisms from necrotic pulp of traumatized teeth. Odontol Revy. 1974. 25 (4): 347–58.

8. Costerton J. W., Cheng K. J., Geesey G. G., Ladd T. I., Nickel J. C., Dasgupta M., et al. Bacterial biofilms in nature and disease. Annu Rev Microbiol [Internet]. 1987 41:435–64.

9. Voběrková S., Hermanová S., Hrubanová K., Krzyžánek V. Biofilm formation and extracellular polymeric substances (EPS) production by Bacillus subtilis depending on nutritional conditions in the presence of polyester film. Folia Microbiol (Praha). 2015.

10. Flemming H-C, Wingender J. The biofilm matrix. Nat Rev Microbiol. 8 (9): 623–33. Available from: http://www.ncbi.nlm.nih. gov/pubmed/20676145

11. Siqueira J. F., Rôças I. N., Ricucci D. Biofilms in endodontic infection. Endod Top. 2010 Mar. 22 (1): 33–49.

12. Marsh P. D. Dental plaque as a microbial biofilm. Caries Res. 38 (3): 204–11.

13. Lima K. C., Coelho L. T., Pinheiro I.V.A., Rôças I. N., Siqueira J. F. Microbiota of dentinal caries as assessed by reverse-capture checkerboard analysis. Caries Res. 2011; 45 (1): 21–30.

14. Munson M. A., Banerjee A., Watson T. F., Wade W. G. Molecular analysis of the microflora associated with dental caries. J. Clin Microbiol. American Society for Microbiology (ASM); 2004 Jul; 42 (7): 3023–9.

15. Costerton W., Veeh R., Shirtliff M., Pasmore M., Post C., Ehrlich G. The application of biofilm science to the study and control of chronic bacterial infections. J. Clin Invest. 2003 Nov; 112 (10): 1466–77.

16. Nair P. N. R., Henry S., Cano V., Vera J. Microbial status of apical root canal system of human mandibular first molars with primary apical periodontitis after one-visit; endodontic treatment. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005 Feb; 99 (2): 231–52.

17. Ricucci D., Siqueira J. F. Apical actinomycosis as a continuum of intraradicular and extraradicular infection: case report and critical review on its involvement with treatment failure. J. Endod. 2008 Sep; 34 (9): 1124–9.

18. Tronstad L., Sunde P. T. The evolving new understanding of endodontic infections. Endod Top. Munksgaard International Publishers; 2003 Nov; 6 (1): 57–77.

19. Svensater G., Bergenholtz G. Biofilms in endodontic infections. Endod Top. Munksgaard International Publishers; 2004 Nov.

20. Parsek M. R., Singh P. K. Bacterial biofilms: an emerging link to disease pathogenesis. Annu Rev Microbiol. 2003. 57: 677–701.

21. Hall-Stoodley L., Stoodley P. Evolving concepts in biofilm infections. Cell Microbiol. 2009; 11 (7): 1034–43.

22. Ricucci D., Siqueira J. F. Biofilms and apical periodontitis: study of prevalence and association with clinical and histopathologic findings. J. Endod. 2010 Aug 36 (8): 1277–88.

23. Nair P. N. R., Henry S., Cano V., Vera J. Microbial status of apical root canal system of human mandibular first molars with primary apical periodontitis after one-visit; endodontic treatment. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005 Feb; 99 (2): 231–52.

24. Friedman S., Abitbol S., Lawrence H. P. Treatment outcome in endodontics: the Toronto Study. Phase 1: initial treatment. J. Endod. 2003 Dec;29 (12): 787–93.

25. Kishen A., Sum C-P, Mathew S., Lim C-T. Influence of irrigation regimens on the adherence of Enterococcus faecalis to root canal dentin. J. Endod. 2008 Jul 2016 Sep 20]; 34 (7): 850–4.

26. Kostakioti M., Hadjifrangiskou M., Hultgren S. J. Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era. Cold Spring Harb Perspect Med. 2013 Apr; 3 (4).

27. Jansen B., Kohnen W. Prevention of biofilm formation by polymer modification. J. Ind Microbiol. 1995 Oct 15 (4): 391–6.

28. Balaban N., Giacometti A., Cirioni O., Gov Y., Ghiselli R., Mocchegiani F., et al. Use of the Quorum-Sensing Inhibitor RNAIII- Inhibiting Peptide to Prevent Biofilm Formation In Vivo by Drug-Resistant Staphylococcus epidermidis. 2003;187.

29. George S., Kishen A. Photophysical, photochemical, and photobiological characterization of methylene blue formulations for lightactivated root canal disinfection. J. Biomed Opt. 12 (3): 34029.

30. Shrestha A., Kishen A. Antibacterial Nanoparticles in Endodontics: A Review. J. Endod. 2016;42(10):1417–26.