2016, Número S2
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Gac Med Mex 2016; 152 (S2)
Estudio comparativo de la eficacia de la larvaterapia (LT) para desbridar y controlar la carga bacteriana en úlceras venosas comparado con desbridamiento quirúrgico y aplicación de un antimicrobiano tópico
Contreras-Ruiz J, Fuentes-Suárez A, Arroyo-Escalante S, Moncada-Barron D, Sosa-de-Martínez MC, Maravilla-Franco E, Domínguez-Cherit JG
Idioma: Español
Referencias bibliográficas: 99
Paginas: 78-87
Archivo PDF: 198.95 Kb.
RESUMEN
La LT es el uso de larvas estériles de la mosca Lucilia sericata para desbridar tejido necrótico. Observaciones recientes
señalan además que reduce la carga bacteriana de las heridas. Las úlceras venosas son el motivo más frecuente de consulta
en las clínicas de heridas y requieren, concomitantemente, del manejo apropiado de la hipertensión venosa, la adecuada
preparación del lecho de la herida con desbridamiento del tejido necrótico y el control de posibles infecciones. Para
evaluar la eficacia de la LT en úlceras venosas se diseñó un estudio controlado aleatorizado para comparar la LT sola
contra el desbridamiento quirúrgico y la aplicación tópica de sulfadiazina de plata (SDP) en 19 pacientes durante 4 semanas.
Las variables estudiadas fueron la reducción del área, las características del lecho de la herida, el dolor, el olor, la ansiedad
y la carga bacteriana utilizando biopsias cuantitativas de tejido. La LT fue tan eficaz como el desbridamiento quirúrgico
asociado a SDP tópica para desbridar la herida y reducir el tamaño de la misma. Se observó una diferencia
significativa en la reducción de la carga bacteriana a favor del grupo de LT. El olor y la ansiedad aumentaron en el grupo
de LT, sin que hubiese diferencia en la intensidad del dolor entre ambos grupos. En conclusión, el presente estudio sugiere
que la LT es tan útil para desbridar y favorecer la cicatrización de la herida como el desbridamiento quirúrgico con cureta
en las úlceras venosas, y demostró ser superior en el control de la carga bacteriana.
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