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2016, Número 4

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Rev Mex Pediatr 2016; 83 (4)


Pubertad precoz central

Zurita-Cruz JN

Idioma: Español
Referencias bibliográficas: 58
Paginas: 133-137
Archivo PDF: 207.50 Kb.


RESUMEN

La pubertad precoz se define como el desarrollo de las características sexuales antes de los nueve años de edad en los varones y de los ocho en las niñas. La pubertad precoz central (PPC) se debe a una activación prematura del eje hipotálamo-hipófisis-gónada. Es más frecuente que se presente en el sexo femenino y que sea de etiología idiopática. Los datos clínicos, además de la presencia de características sexuales secundarias, son la edad ósea adelantada y una velocidad de crecimiento acelerada. El tratamiento de primera línea son los análogos de la hormona liberadora de gonadotropinas (aGnRH). Se sugiere realizar la suspensión del tratamiento cuando las niñas alcanzan una edad ósea de 12 años y los varones de 14. El inicio del tratamiento antes de los seis años de edad es un factor de buen pronóstico para la estatura adulta final. No existen suficientes estudios para evaluar a largo plazo el desarrollo de síndrome de ovario poliquístico y factores cardiometabólicos en etapa adulta en las mujeres con el antecedente de PPC. El pediatra debe realizar una revisión completa del paciente pediátrico al realizar el seguimiento de crecimiento y desarrollo, donde incluya revisión del estadio de Tanner.


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