Cárdenas-Membrila G Escamilla-Illescas D, Cárdenas-Ortega A

Idioma: Español
Referencias bibliográficas: 21
Paginas: 118-123
Archivo PDF: 121.94 Kb.

RESUMEN

La lesión renal aguda (LRA) se refiere a una rápida disminución de la función renal excretora con acumulación de metabolitos del nitrógeno. En los últimos años ha tomado importancia debido al incremento en morbilidad, mortalidad y a la progresión a cronicidad. El diagnóstico de esta entidad resulta complejo debido a la poca homogeneidad en los criterios diagnósticos y los factores que favorecen su desarrollo. La definición de LRA y clasificación de acuerdo con RIFLE y AKIN, basados en los cambios primarios y desenlaces terminales, han abierto el panorama para incorporar la LRA como un problema prevenible y tratable desde estadios tempranos por lo que es importante destacar fisiopatológicamente los factores predisponentes, así como los insultos que derivan en la progresión a LRA. Actualmente es importante la estandarización y el uso de criterios unificados para el diagnóstico oportuno, prevención de cronicidad y generación de nueva información.

REFERENCIAS (EN ESTE ARTÍCULO)

1. Bellomo R, Kellum JA, Ronco C. Acute kidney injury. Lancet 2012; 380: 756-66.

2. Chertow GM, Burdick E, Honour M, Bonvetre JV, Bates DW. Acute kidney injury, mortality, length of stay, and cost in hospitalized patients. J Am SocNephrol 2005; 16: 3365-70.

3. Ronco C. Kidney attack: Overdiagnosis of AKI or comprehensive definition of Acute Kidney Syndromes? Blood Purif 2013; 36: 65-8.

4. Hoste E, De Corte W. Implementing the kidney Disease: Improving global outcomes/acute kidney injury guidelines in ICU patients. Curr Opin Crit Care 2013; 19: 544-53.

5. Eknoyan G. Emergence of the concept of Acute Kidney Injury. Adv Chronic Kidney Dis 2008; 15: 308-13.

6. Eknoyan G. Emergence of the concept of Acute Renal Failure. Am J Nephrol 2001; 22: 225-30.

7. Garzotto F, Piccinni P, Cruz D, Gramaticopolo S, Dal Santo M, Aneloni G, Kim JC, et al. RIFLE-Based data collection/management system applied to a Prospective Cohort Multicenter Italian Study on the epidemiology of Acute Kidney Injury in the Intensive Care Unit. Blood Purif 2011; 31: 159-71.

8. Costa e Silva VT, Liaño F, Muriel A, Díez R, de Castro I, Yu L. Nephrology Referral and Outcomes in Critical Ill Acute Kidney Injury patients. PLoS ONE 2013; 8: e70482.

9. Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group. KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney inter 2012; 2(Suppl.): 1-138.

10. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P; Acute Dialysis Quality Initiative workgroup. Acute renal failure definition, outcomes measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Intiativa (ADQI) Group. Crit Care 2004; 8: R204-R212.

11. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007; 11: R31.

12. Lopes JA, Fernandes P, Jorge S, Goncalves S, Alvarez A, Costa e Silva Z, Franca C, et al. Acute kidney injury in intensive care unit patients: A comparison between the RIFLE and the Acute Kidney Injury Network classifications. Crit Care 2008; 12: R110.

13. Poukkanen M, Wilkman E, Vaara ST, Peeilä V, Kaukonen KM, Korhonen AM, Uusaro A, et al. Hemodynamic variables and progression of acute kidney injury in critically ill patients with severe sepsis: data from the prospective observational FINNAKI study. Critical Care 2013; 17: R295.

14. Dennen P, Douglas IS, Anderson R. Acute kidney injury in the intensive care unit: an update and primer for the intensivist. Crit Care Med 2010; 38: 261-75.

15. Bagshaw SM, George C, Bellomo R, ANZINCS Database Management Committe. A comparison of the RIFLE and AKIN criteria for acute kidney injury in critically ill patients. Nephrol Dial Transplant 2008; 23: 1569-74.

16. Lameire NH, Bagga A, Cruz D, De Maeseneer J, Endre Z, Kellum JA, Lui KD, et al. Acute kidney injury: an increasing global concern. Lancet 2013; 382: 170-9.

17. Traynor J, Mactier R, Geddes CC, Fox JG. How to measure renal function in clinical practice. BMJ 2006; 333: 733-7.

18. Macedo E, Bouchard J, Soroko SH, Chertow GM, Himmelfarb J, Ikizler TA, Paganini EP, et al. Fluid accumulation, recognition and staging of acute kidney injury in critically-ill patients. Critical Care 2010; 14: R82.

19. Carter JL, Lamb EJ. Evaluating new biomarkers for Acute Kidney Injury: putting the horse before the cart. Am J Kidney Dis 2014; 63(4): 543-6.

20. McCoullough PA, Kellum JA, Mehta RL, Murray PT, Ronco C (eds). ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes. Contrib Nephrol 2013; 182: 5-12. 21. Singbartl K, Kellum JA. AKI in the ICU: definition, epidemiology, risk stratification and outcomes. Kidney International 2012; 81: 819-25.

21. Kashani K, Herasevich V. Sniffing out Acute Kidney Injury in the ICU: do we have the tools? Curr Opin Crit Care 2013; 19: 531-6.