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2016, Número 3

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Rev Med MD 2016; 7.8 (3)


Necrosis cutánea extensa como primera manifestación de síndrome de anticuerpos antifosfolípidos primario: Reporte de caso y revisión de la literatura

Zaragoza-Valdez DL, Gutiérrez-Ureña SR, Bernard-Medina AG, Martínez-Bonilla G, González-Díaz V, Cerpa-Cruz S, García-Espinosa LA

Idioma: Español
Referencias bibliográficas: 15
Paginas: 191-195
Archivo PDF: 1140.86 Kb.


RESUMEN

El síndrome de anticuerpos antifosfolípidos se manifiesta clínicamente con trombosis y/o pérdidas fetales recurrentes, también es común presentar anemia autoinmune, manifestaciones neurológicas y en piel. De las manifestaciones en piel, la necrosis cutánea extensa es la menos frecuente. Reportamos el caso de una mujer de 64 años de edad, que presenta necrosis cutánea extensa como primer manifestación de síndrome de anticuerpos antifosfolípidos primario, ya que hay pocos casos reportados históricamente.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. Cervera R, Piette J, Font J, Khamashta MA, Shoenfeld Y, Camps T, et al. Antiphospholipid Syndrome Clinical and Immunologic Manifestations and Patterns of Disease Expression in a Cohort of 1000 patients. Arthritis Rheum 2002;46(4):1019–27.

  2. Pinto-almeida T, Caetano M, Sanches M, Selores M. Cutaneous manifestations of antiphospholipid syndrome: A review of the clinical features, diagnosis and management. Acta Reumatol Port. 2013;10–8.

  3. Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost. England; 2006 Feb;4(2):295–306.

  4. Neill AO, Gatenby PA, Mcgaw B, Painter DM. Widespread cutaneous necrosis associated with cardiolipin antibodies. Journal of the American Academy of Dermatology 1990;356–9.

  5. Amster MS, Conway J, Zeid M, Pincus S. Cutaneous necrosis resulting from protein S deficiency and increased antiphospholipid antibody in a patient with systemic lupus erythematosus. J Am Acad Dermatol. American Academy of Dermatology, Inc.; 1993;29(5 Pt 2):853–7.

  6. Soweid AM, Hajjar RR, Hewan-Lowe KO, Gonzalez EB. Skin necrosis indicating antiphospholipid syndrome in patient with AIDS. South Med J. UNITED STATES; 1995 Jul;88(7):786–8.

  7. Jou I. Case Report Widespread Cutaneous Necrosis Associated with Antiphospholipid Syndrome. Clin Rheumatol. 1996 Jul;15(4):394-8.

  8. Fiehn C, Breitbart A, Germann G. Autologous skin transplantation for widespread cutaneous necrosis in secondary antiphospholipid syndrome. Ann Rheum Dis 2001;60:908–910.

  9. Creamer D, Hunt BJ, Black MM. Widespread cutaneous necrosis occurring in association with the antiphospholipid syndrome: A report of two cases. Br J Dermatol. 2000;142(6):1199–203.

  10. Rossini J, Roverano S, Graf C, Paira S. Widespread cutaneous necrosis associated with antiphospholipid antibodies: report of four cases. J Clin Rheumatol. 2002;8(6):326–31.

  11. DiFrancesco LM, Burkart P, Hoehn JG. A Cutaneous Manifestation of Antiphospholipid Antibody Syndrome. Ann Plast Surg. 2003;51(5):517–22.

  12. Costa R, Fazal S, Kaplan RB, Spero J, Costa R. Successful plasma exchange combined with rituximab therapy in aggressive APS-related cutaneous necrosis. Clin Rheumatol. 2013;32(SUPPL. 1):79–82.

  13. De Souza A, Capriglione ML, Fernandes J. Necrose cutanea extensa como primeira manifestacao da sindrome antifosfolipidica (SAF) secundaria. Acta Reumatologica Portuguese 2010;35:244-248.

  14. Aghdashi M, Aghdashi M, Rabiepoor M. Cutaneous necrosis of lower extremity as the fi rst manifestation of catastrophic antiphospholipid syndrome. Mod Rheumatol. 2015 May;25(3):490-2.

  15. Alegre VA, Gastineau DA, Winkelmann RK. Skin lesions associated with circulating lupus anticoagulant. Br J Dermatol. ENGLAND; 1989 Mar;120(3):419–29.




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