2015, Número 4
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Rev Cubana Hematol Inmunol Hemoter 2015; 31 (4)
Trombosis y trasplante de progenitores hematopoyéticos: patogénesis y complicaciones trombóticas más frecuentes
Roque GW, Jaime FJC
Idioma: Español
Referencias bibliográficas: 61
Paginas: 349-361
Archivo PDF: 111.69 Kb.
RESUMEN
Las complicaciones trombóticas son comunes en el contexto del trasplante de células progenitoras hematopoyéticas. El daño al endotelio vascular aparece como el factor desencadenante en la cascada de evento que conlleva a la trombosis en el paciente trasplantado. Estas complicaciones son diversas y aparecen en las fases
inmediatas o tardías. El síndrome de obstrucción sinusoidal hepático, caracterizado por trombosis en los pequeños vasos de la microcirculación, constituye la
complicación más frecuente y mejor estudiada. En este trabajo se revisa la patogénesis de las complicaciones trombóticas en el paciente con trasplante de células progenitoras hematopoyéticas y se describen las más frecuentes.
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